Publication: Cell fusion induced by Germiston and Wesselsbron viruses
Issued Date
1973-03-01
Resource Type
ISSN
14328798
03048608
03048608
Other identifier(s)
2-s2.0-34250439750
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Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Archiv für die gesamte Virusforschung. Vol.43, No.1-2 (1973), 144-151
Suggested Citation
N. K. Djinawi, L. C. Olson Cell fusion induced by Germiston and Wesselsbron viruses. Archiv für die gesamte Virusforschung. Vol.43, No.1-2 (1973), 144-151. doi:10.1007/BF01249357 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/10111
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Title
Cell fusion induced by Germiston and Wesselsbron viruses
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Abstract
Both Germiston and Wesselsbron viruses were found to rapidly induce polykaryocytosis when added to cell cultures; the immediate nature of the reaction suggested that the mechanism was fusion from without. Mouse peritoneal macrophages and Vero, LLC-MK2, Aedes albopictus and L cells were susceptible to fusion. Chloroform treatment did not affect the ability of either virus to induce cell fusion even though the infectivity of Germiston virus was completely destroyed by chloroform. When chloroform-inactivated virus was added to cell cultures at high multiplicities, all cells in the monolayer were fused into a single syncytium. © 1973 Springer-Verlag.