The feasibility of using the go/no-go task as a dementia screening test assessed with a cross-sectional design
Issued Date
2024-12-01
Resource Type
eISSN
20452322
Scopus ID
2-s2.0-85211185910
Journal Title
Scientific Reports
Volume
14
Issue
1
Rights Holder(s)
SCOPUS
Bibliographic Citation
Scientific Reports Vol.14 No.1 (2024)
Suggested Citation
Watanabe N., Kamijo M., Nishino T., Ashida K., Sasamori F., Okuhara M., Maruo S.J., Tabuchi H., Terasawa K. The feasibility of using the go/no-go task as a dementia screening test assessed with a cross-sectional design. Scientific Reports Vol.14 No.1 (2024). doi:10.1038/s41598-024-81301-5 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/102381
Title
The feasibility of using the go/no-go task as a dementia screening test assessed with a cross-sectional design
Corresponding Author(s)
Other Contributor(s)
Abstract
The Mini Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), and Frontal Assessment Battery are screening tests for dementia. The go/no-go task offers an alternative approach for evaluating dementia patients. However, its role in screening for dementia remains unclear. We aimed to explore the feasibility of using the go/no-go task as a screening test for dementia via a cross-sectional design. Twenty-four Japanese individuals were evaluated using the go/no-go task, the MMSE, and the MoCA. The total MMSE and MoCA scores were correlated with the total number of errors in the go/no-go task (r=-0.699, p < 0.01; r=-0.756, p < 0.01). Moreover, When the MoCA cutoff value was 25 for MCI, the optimal cutoff score for the total number of error in the go/no-go task to detect MCI was 2, with an Area Under curve (AUC) of 0.98, a sensitivity of 0.94. When the MMSE cutoff value was 27 for MCI, the optimal cutoff score for the total number of error in the go/no-go task to detect MCI was 6, with an AUC of 0.89, a sensitivity of 0.76, showed respectively values close to 1. The go/no-go task is possible a practical screening test for dementia.