Publication:
Ferritin synthesis in peripheral blood lymphocytes following in vitro stimulation*

Issued Date

1989-01-01

Resource Type

Article

ISSN

16000609
09024441

DOI

10.1111/j.1600-0609.1989.tb01470.x

Other identifier(s)

2-s2.0-0024370346

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

European Journal of Haematology. Vol.42, No.5 (1989), 454-459

Suggested Citation

Kovit Pattanapanyasat Ferritin synthesis in peripheral blood lymphocytes following in vitro stimulation*. European Journal of Haematology. Vol.42, No.5 (1989), 454-459. doi:10.1111/j.1600-0609.1989.tb01470.x Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/15824

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Title

Ferritin synthesis in peripheral blood lymphocytes following in vitro stimulation*

Author(s)

Kovit Pattanapanyasat

Other Contributor(s)

Mahidol University

Abstract

The incubation of normal peripheral blood lymphocytes with phytohaemagglutinin results in an increase in DNA synthesis accompanied by an increase in ferritin synthesis, as determined by 3 H‐leucine incorporation into ferritin isolated by immunoprecipitation. The increase was 5 to 8 times greater than that of non‐stimulated cells. This phenomenon was associated with a 3‐ to 6‐fold increase of intracellular ferritin when compared with the original ferritin concentration. While the significance of increased ferritin expression in proliferative cells is not known, an increase in ferritin synthesis following in vitro stimulation is probably related to increased metabolic activity of the cells. © Munksgaard 1989

Keyword(s)

Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/15824

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Scopus 1969-1990