Publication:
Long‐Term Immunoprophylaxis of Hepatitis B Surface Antigen Carrier in Infants Born to Hepatitis B Surface Antigen Positive Mothers Using Plasma Derived Vaccine

Issued Date

1989-01-01

Resource Type

Article

ISSN

14470756
03892328

DOI

10.1111/j.1447-0756.1989.tb00162.x

Other identifier(s)

2-s2.0-0024678950

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Asia‐Oceania Journal of Obstetrics and Gynaecology. Vol.15, No.2 (1989), 111-115

Suggested Citation

Urusa Theppisai, Chalermsri Thanuntaseth, Pimol Chiewsilp, Praput Siripoonya Long‐Term Immunoprophylaxis of Hepatitis B Surface Antigen Carrier in Infants Born to Hepatitis B Surface Antigen Positive Mothers Using Plasma Derived Vaccine. Asia‐Oceania Journal of Obstetrics and Gynaecology. Vol.15, No.2 (1989), 111-115. doi:10.1111/j.1447-0756.1989.tb00162.x Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/15840

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Title

Long‐Term Immunoprophylaxis of Hepatitis B Surface Antigen Carrier in Infants Born to Hepatitis B Surface Antigen Positive Mothers Using Plasma Derived Vaccine

Author(s)

Urusa Theppisai
 Chalermsri Thanuntaseth
 Pimol Chiewsilp
 Praput Siripoonya

Other Contributor(s)

Mahidol University

Abstract

Immunoprophylaxis of HBV infection using 3 doses (10 μg) of plasma derived HBV vaccine were given to 49 newborn infants of e‐antigen negative HBs Ag carrier mothers at birth, one and 6 months of age. The protective efficacy rate was 100% during first 2 years. At 3 years of age, HBs Ag carrier was 2.63% and 89.48% of infants had anti‐HBs above the protective level. Ten point fifty‐two percent of total infants had anti‐HBs level below 10 mIU/ml and 21.05% had anti‐HBs level between 10–100 mIU/ml. Most infants who had the maximal level of antibody below 100 mIU/ml had lost all antibody within 3 years. The loss of antibody was closely related to the maximal anti‐HBs titer (one year of age) which is highly predictive indicator of the longevity of anti‐HBs. © 1989 Japanese Society of Obstetrics and Gynaecology

Keyword(s)

Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/15840

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Scopus 1969-1990