Publication: Acaricidal daphnane diterpenoids from Trigonostemon reidioides (KURZ) CRAIB roots
Issued Date
2005-02-01
Resource Type
ISSN
00092363
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2-s2.0-19444380411
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Mahidol University
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SCOPUS
Bibliographic Citation
Chemical and Pharmaceutical Bulletin. Vol.53, No.2 (2005), 241-243
Suggested Citation
Noppamas Soonthornchareonnon, Monnun Sakayarojkul, Masahiko Isaka, Vanna Mahakittikun, Wongsatit Chuakul, Prapai Wongsinkongman Acaricidal daphnane diterpenoids from Trigonostemon reidioides (KURZ) CRAIB roots. Chemical and Pharmaceutical Bulletin. Vol.53, No.2 (2005), 241-243. doi:10.1248/cpb.53.241 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/16454
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Title
Acaricidal daphnane diterpenoids from Trigonostemon reidioides (KURZ) CRAIB roots
Abstract
A new daphnane diterpenoid, rediocide F (1), was isolated together with three known compounds, rediocides A (2), C (3) and E (4), from the hexane extract of Trigonostemon reidioides roots by bioassay-guided fractionation for acaricidal activity on Dermatophagoides pteronyssinus, Thai common house dust mite. The structure of rediocide F (1) was established as the demethyl analog of rediocide C (3) on the basis of spectral analysis. Compounds 1-4 exhibited potent activity against D. pteronyssinus with respective LC50 values of 2.53, 0.78, 5.59 and 0.92 μg/cm2. © 2005 Pharmaceutical Society of Japan.