Hematopoietic SCT was first performed in Thailand in 1986. At present, there are FOUR active centers: Siriraj, Ramathibodi, Chulalongkorn and Pramongkutklao Hospitals. The annual number of transplants varies from 120 to 150 cases. Although the number of eligible patients is high, only a proportion of the patients can undergo hematopoietic SCT due to the high cost of the procedure. The overall results are comparable to those reported in the Western countries. The incidence of acute GVHD is low, whereas chronic GVHD is high, especially in those who receive PBSC.