Publication: Ultrastructural changes in various organs of the fish Puntius gonionotus fed cadmium-enriched cyanobacteria
Issued Date
2004-12-08
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ISSN
15204081
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2-s2.0-9344271163
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Mahidol University
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SCOPUS
Bibliographic Citation
Environmental Toxicology. Vol.19, No.6 (2004), 585-593
Suggested Citation
N. Rangsayatorn, M. Kruatrachue, P. Pokethitiyook, E. S. Upatham, G. R. Lanza, S. Singhakaew Ultrastructural changes in various organs of the fish Puntius gonionotus fed cadmium-enriched cyanobacteria. Environmental Toxicology. Vol.19, No.6 (2004), 585-593. doi:10.1002/tox.20066 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/21321
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Title
Ultrastructural changes in various organs of the fish Puntius gonionotus fed cadmium-enriched cyanobacteria
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Abstract
The accumulation and toxicity of cadmium in Puntius gonionotus fish that consumed the cyanobacterium Spirulina platensis contaminated with cadmium were studied. Fish were fed cadmium-contaminated cells for 4 weeks, after which cadmium accumulation in various organs was determined. The highest cadmium content was found in the kidney (56.0 μg Cd/g wet weight). Cadmium was not detected in the gill during the entire 4 weeks of cadmium feeding. Histopathological alteration of cells was observed in the gill, kidney, and liver. The results showed that dietary cadmium caused hypertrophy and edema of gill filaments. Coagulative necrosis and karyolysis of the nucleus were observed in the kidney. Vacuoles and hyaline droplets had accumulated in the epithelial cells of the proximal tubule. In the liver vacuolation of the cytoplasm, infiltration of macrophages, and focal necrosis were found. The ultrastructural changes that occurred in the cells of different organs were similar. These included a proliferation of vacuoles and lysosomes, formation of myelin bodies, degranulation, vesiculation, and dilation of rough endoplasmic reticulum, as well as swelling of mitochondria with loss of cristae. © 2004 Wiley Periodicals, Inc.