Publication: Silent transmission of virus during a dengue epidemic, Nakhon Pathom Province, Thailand 2001
Issued Date
2006-09-01
Resource Type
ISSN
01251562
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2-s2.0-33751564681
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Mahidol University
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SCOPUS
Bibliographic Citation
Southeast Asian Journal of Tropical Medicine and Public Health. Vol.37, No.5 (2006), 899-903
Suggested Citation
Thaval Poblap, Narong Nitatpattana, Aree Chaimarin, Philippe Barbazan, Gilles Chauvancy, Sutee Yoksan, Jean Paul Gonzalez Silent transmission of virus during a dengue epidemic, Nakhon Pathom Province, Thailand 2001. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.37, No.5 (2006), 899-903. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/23631
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Title
Silent transmission of virus during a dengue epidemic, Nakhon Pathom Province, Thailand 2001
Abstract
In the year 2001 a large dengue fever (DF)/dengue hemorrhagic fever (DHF) outbreak occurred in Nakhon Pathom Province, Thailand. Three thousand one hundred twelve cases of DHF were reported, an attack rate of 393 per 100,000 population. The Nakhon Pathom Provincial Health Office Immediately carried out a control action according to WHO recommendations. Active serological surveys and viral RNA isolation were carried out to detect silent transmission of dengue virus in 329 healthy volunteers in Nakhon Pathom Province subdistricts where the dengue epidemic had the highest rate of infection of 2.5 per 1,000. Eight point eight percent of these volunteers had a serum sample positive for DF/DHF virus IgM antibody. The highest prevalence occurred in the 15 to 40 year old group. In two instances viral RNA was detected by PCR and dengue serotype 3 was subsequently identified. The data support the hypothesis of subclinical infection with dengue virus. This high frequency of virus circulation combined with a high population density, urbanization and increasing breeding sites for mosquitoes, needs to be taken into account In the evaluation of viral transmission during and after epidemics. This underlines the importance of community-based control in informing people of their involvement in virus transmission and the importance of personal protection.