Publication:
Synthesis of 4-aryltetrahydroisoquinolines: Application to the synthesis of cherylline

Issued Date

2001-04-01

Resource Type

Article

ISSN

03855414

DOI

10.3987/COM-01-9167

Other identifier(s)

2-s2.0-0035307110

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Heterocycles. Vol.55, No.4 (2001), 635-640

Suggested Citation

Somsak Ruchirawat, Sopchok Tontoolarug, Poolsar Sahakitpichan Synthesis of 4-aryltetrahydroisoquinolines: Application to the synthesis of cherylline. Heterocycles. Vol.55, No.4 (2001), 635-640. doi:10.3987/COM-01-9167 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/26514

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Title

Synthesis of 4-aryltetrahydroisoquinolines: Application to the synthesis of cherylline

Author(s)

Somsak Ruchirawat
 Sopchok Tontoolarug
 Poolsar Sahakitpichan

Other Contributor(s)

Chulabhorn Research Institute
 Mahidol University
 The Institute of Science and Technology for Research and Development, Mahidol University

Abstract

A concise route for the synthesis of 4-aryltetrahydroisoquinolines was developed using the addition of Grignard reagents to nitrostyrene derivatives as the key step. The application to the synthesis of cherylline was described.

Keyword(s)

Chemistry
 Pharmacology, Toxicology and Pharmaceutics

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/26514

Collections

Scopus 2001-2005