Publication:
Studies of Zoapatle I. The Extraction of Zoapatle (Montanoa Tomentosa) and the Identification of 21 -normontanol as the Initial Decomposition Product of Zoapatanol

Issued Date

1985-01-01

Resource Type

Article

ISSN

15206025
01633864

DOI

10.1021/np50041a004

Other identifier(s)

2-s2.0-0022359390

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Journal of Natural Products. Vol.48, No.5 (1985), 739-745

Suggested Citation

Guido B. Marcelle, Nuntavan Bunyapraphatsara, Geoffrey A. Cordell, Harry H.S. Fong, Kyriakos C. Nicolaou, Robert E. Zipkin Studies of Zoapatle I. The Extraction of Zoapatle (Montanoa Tomentosa) and the Identification of 21 -normontanol as the Initial Decomposition Product of Zoapatanol. Journal of Natural Products. Vol.48, No.5 (1985), 739-745. doi:10.1021/np50041a004 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/30762

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Title

Studies of Zoapatle I. The Extraction of Zoapatle (Montanoa Tomentosa) and the Identification of 21 -normontanol as the Initial Decomposition Product of Zoapatanol

Author(s)

Guido B. Marcelle
 Nuntavan Bunyapraphatsara
 Geoffrey A. Cordell
 Harry H.S. Fong
 Kyriakos C. Nicolaou
 Robert E. Zipkin

Other Contributor(s)

University of Illinois at Chicago
 Mahidol University
 University of Pennsylvania

Abstract

Hot H2O and hexane were found to be inappropriate to extract zoapatanol (1) from the leaves of Montanoa tomentosa ssp. tomentosa; EtOH and EtOAc, on the other hand, were far more effective. A number of Montanoa species and subspecies were examined for the presence of zoapatanol (1). Zoapatanol is highly unstable either neat or in aqueous solution at elevated temperatures, and only samples dissolved in solvent and stored at — 5 to — 10° have extended half-lives. The initial decomposition product of zoapatanol (1) has been identified as 21-normontanol (2) through high field proton nmr analysis. © 1985, American Chemical Society. All rights reserved.

Keyword(s)

Biochemistry, Genetics and Molecular Biology
 Chemistry
 Medicine
 Pharmacology, Toxicology and Pharmaceutics

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/30762

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Scopus 1969-1990