Publication: Bridged tricyclic sesquiterpenes from the tubercle nudibranch Phyllidia coelestis Bergh
Issued Date
2013-11-22
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ISSN
15206025
01633864
01633864
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2-s2.0-84888365974
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of Natural Products. Vol.76, No.11 (2013), 2158-2161
Suggested Citation
Sunan Jaisamut, Samran Prabpai, Chompoonuch Tancharoen, Supreeya Yuenyongsawad, Supa Hannongbua, Palangpon Kongsaeree, Anuchit Plubrukarn Bridged tricyclic sesquiterpenes from the tubercle nudibranch Phyllidia coelestis Bergh. Journal of Natural Products. Vol.76, No.11 (2013), 2158-2161. doi:10.1021/np4007074 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/31161
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Title
Bridged tricyclic sesquiterpenes from the tubercle nudibranch Phyllidia coelestis Bergh
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Abstract
A new sesquiterpene, 1-formamido-10(1→2)-abeopupukeanane (1), was isolated from the tubercle nudibranch Phyllidia coelestis Bergh, along with 2-formamidopupukeanane (2), which is reported here as a natural product for the first time. A rearrangement pathway toward the unprecedented tricyclo[4.4.0.02,8]decane skeleton is proposed. Both compounds showed antiproliferative activity when targeting HeLa, MCF-7, KB, and HT-29 cancer cell lines in the range 0.05-10 μM. © 2013 The American Chemical Society and American Society of Pharmacognosy.