Publication: Advances in management of hepatocellular carcinoma
Issued Date
2016-01-01
Resource Type
ISSN
15137368
Other identifier(s)
2-s2.0-84988382957
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Asian Pacific Journal of Cancer Prevention. Vol.17, No.8 (2016), 3697-3703
Suggested Citation
Pongphob Intaraprasong, Sith Siramolpiwat, Ratha Korn Vilaichone Advances in management of hepatocellular carcinoma. Asian Pacific Journal of Cancer Prevention. Vol.17, No.8 (2016), 3697-3703. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/43237
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Advances in management of hepatocellular carcinoma
Other Contributor(s)
Abstract
Hepatocellular carcinoma (HCC) is the most frequent type of malignant liver tumor and a high impact health problem worldwide. The prevalence of HCC is particularly high in many Asian and African countries. Some HCC patients have no symptoms prior to diagnosis and many of them therefore present at late stage and have a grave prognosis. The well-established causes of HCC are chronic hepatitis B virus (HBV) or chronic hepatitis C virus (HCV) infection or alcoholic cirrhosis and nonalcoholic steatohepatitis. The Barcelona Clinic Liver Cancer (BCLC) Staging System remains the most widely used for HCC management guidelines. To date, the treatments for HCC are still very challenging for physicians due to limited resources in many parts of the world, but many options of management have been proposed, including hepatic resection, liver transplantation, ablative therapy, chemoembolization, sorafinib and best supportive care. This review article describes the current evidence-based management of HCC with focus on early to advance stages that impact on patient overall survival.