Publication: Hypertension and erectile dysfunction: The role of endovascular therapy in Asia
Issued Date
2021-03-01
Resource Type
ISSN
17517176
15246175
15246175
Other identifier(s)
2-s2.0-85097543396
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Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Clinical Hypertension. Vol.23, No.3 (2021), 481-488
Suggested Citation
Tzung Dau Wang, Chih Kuo Lee, Yook Chin Chia, Kelvin Tsoi, Peera Buranakitjaroen, Chen Huan Chen, Hao Min Cheng, Jam Chin Tay, Boon Wee Teo, Yuda Turana, Guru Prasad Sogunuru, Ji Guang Wang, Kazuomi Kario Hypertension and erectile dysfunction: The role of endovascular therapy in Asia. Journal of Clinical Hypertension. Vol.23, No.3 (2021), 481-488. doi:10.1111/jch.14123 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/78420
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Title
Hypertension and erectile dysfunction: The role of endovascular therapy in Asia
Other Contributor(s)
Siriraj Hospital
Sunway University
Jichi Medical University
Shanghai Jiao Tong University School of Medicine
Madras Institute of Orthopaedics and Traumatology Hospitals
National Taiwan University Hospital
Kathmandu University
National Yang-Ming University Taiwan
Universitas Katolik Indonesia Atma Jaya
Universiti Malaya
NUS Yong Loo Lin School of Medicine
Veterans General Hospital-Taipei
Chinese University of Hong Kong
Tan Tock Seng Hospital
Sunway University
Jichi Medical University
Shanghai Jiao Tong University School of Medicine
Madras Institute of Orthopaedics and Traumatology Hospitals
National Taiwan University Hospital
Kathmandu University
National Yang-Ming University Taiwan
Universitas Katolik Indonesia Atma Jaya
Universiti Malaya
NUS Yong Loo Lin School of Medicine
Veterans General Hospital-Taipei
Chinese University of Hong Kong
Tan Tock Seng Hospital
Abstract
The prevalence of erectile dysfunction (ED) is above 40% in both Asian and non-Asian male populations after the age of 40 years. The prevalence of ED among hypertensive patients is approximately double than that in normotensive population. Pelvic arterial insufficiency is the predominant cause of ED in men aged over 50 years. Stenosis in any segment of the iliac–pudendal–penile arterial system, which is considered an erectile-related arterial axis, could lead to ED. Pharmacotherapy with lifestyle modification is effective in alleviating sexual dysfunction, yet a substantial number of patients still develop ED. Given the established applicability of angioplasty for the entire iliac–pudendal–penile arterial system, penile duplex ultrasound, and pelvic computed tomography angiography could be considered as the routine screening tools in ED patients with poor response to phosphodiesterase-5 inhibitors. Endovascular therapy for pelvic arterial insufficiency-related ED has been shown to be a safe and effective treatment option in patients who have anatomically suitable vessels and functionally significant stenoses. Clinical improvement was achieved in over 60% of patients at one year following pelvic angioplasty in the PERFECT registry from Taiwan. A 30%-40% restenosis rate in distal internal pudendal and penile arteries remains a hurdle. Angioplasty for pelvic arterial occlusive disease could be considered as a viable approach to arteriogenic ED.