Talarostatin, a vermistatin derivative from the soil-derived fungus Talaromyces thailandensis PSU-SPSF059
Issued Date
2023-01-01
Resource Type
ISSN
14786419
eISSN
14786427
Scopus ID
2-s2.0-85150735369
Pubmed ID
36919631
Journal Title
Natural Product Research
Rights Holder(s)
SCOPUS
Bibliographic Citation
Natural Product Research (2023)
Suggested Citation
Ningsih B.N.S., Rukachaisirikul V., Phongpaichit S., Muanprasat C., Preedanon S., Sakayaroj J., Intayot R., Jungsuttiwong S. Talarostatin, a vermistatin derivative from the soil-derived fungus Talaromyces thailandensis PSU-SPSF059. Natural Product Research (2023). doi:10.1080/14786419.2023.2188209 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/81766
Title
Talarostatin, a vermistatin derivative from the soil-derived fungus Talaromyces thailandensis PSU-SPSF059
Other Contributor(s)
Abstract
The soil-derived fungus Talaromyces thailandensis PSU-SPSF059 produced one new vermistatin derivative, talarostatin, and seven known compounds including two vermistatins, two chrodrimanins, two diphenyl ethers and one penicillide derivative. Extensive spectroscopic analysis was performed to identify their structures. The absolute configuration of talarostatin was determined by comparing the experimental and calculated electronic circular dichroism data. The antimicrobial and cytotoxic activities of the isolated secondary metabolites were also evaluated.