Early bone reformation after cranial vault remodelling for sagittal craniosynostosis: A retrospective 3D analysis
Issued Date
2023-01-01
Resource Type
ISSN
10105182
eISSN
18784119
Scopus ID
2-s2.0-85152145946
Journal Title
Journal of Cranio-Maxillofacial Surgery
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Cranio-Maxillofacial Surgery (2023)
Suggested Citation
Chaisrisawadisuk S., Phakdeewisetkul K., Sirichatchai K., Tongsai S., Hammam E., Prasad V., Moore M.H. Early bone reformation after cranial vault remodelling for sagittal craniosynostosis: A retrospective 3D analysis. Journal of Cranio-Maxillofacial Surgery (2023). doi:10.1016/j.jcms.2023.04.003 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/81820
Title
Early bone reformation after cranial vault remodelling for sagittal craniosynostosis: A retrospective 3D analysis
Author's Affiliation
Other Contributor(s)
Abstract
This study aims to measure postoperative bone reformation percentage, rates and patterns after cranial vault remodelling (CVR) in isolated non-syndromic sagittal craniosynostosis. Volumetric bone measurements were performed starting from the DICOM files of previously available postoperative CT scans. The 3D images were then resampled into the master box, and ‘Skull 3D models’ were derived. The percentage of bone reformation was investigated using automated 3D analysis software. The intra-rater reliability analysis revealed high reliability (Intraclass correlation coefficient = 0.99, p < 0.001). The median bone reformation volume and rate were 11.2 ml and 1.98 ml/week, respectively. The median percentage of bone reformation was 56.7% when the median postoperative CT timing was 6.1 weeks. As a statistic model, the linear plateau showed the highest Pseudo R2 in both volume and percentage of bone reformation predicting patterns. By using the calculated model at 9 weeks postoperatively, the re-osteogenesis reaches 80% of the total cranial defect. After CVR, the early bone reformation pattern was demonstrated as a linear plateau model rather than logarithmic. This study gives a better understanding of the pattern and quantity of re-osteogenesis at cranial defects after CVR. The statistic model can facilitate healthcare practitioners to predict bone reformation and improve postoperative care protocol in sagittal craniosynostosis management.