One Health Surveillance of Antimicrobial Resistance Phenotypes in Selected Communities in Thailand
Issued Date
2022-05-01
Resource Type
eISSN
20796382
Scopus ID
2-s2.0-85129427725
Journal Title
Antibiotics
Volume
11
Issue
5
Rights Holder(s)
SCOPUS
Bibliographic Citation
Antibiotics Vol.11 No.5 (2022)
Suggested Citation
Sudatip D., Tiengrim S., Chasiri K., Kritiyakan A., Phanprasit W., Morand S., Thamlikitkul V. One Health Surveillance of Antimicrobial Resistance Phenotypes in Selected Communities in Thailand. Antibiotics Vol.11 No.5 (2022). doi:10.3390/antibiotics11050556 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/83750
Title
One Health Surveillance of Antimicrobial Resistance Phenotypes in Selected Communities in Thailand
Other Contributor(s)
Abstract
Integrated surveillance of antimicrobial resistance (AMR) using the One Health approach that includes humans, animals, food, and the environment has been recommended by responsible international organizations. The objective of this study was to determine the prevalence of AMR phenotypes in Escherichia coli and Klebsiella species isolated from humans, pigs, chickens, and wild rodents in five communities in northern Thailand. Rectal swabs from 269 pigs and 318 chickens; intestinal contents of 196 wild rodents; and stool samples from 69 pig farmers, 155 chicken farmers, and 61 non-farmers were cultured for E. coli and Klebsiella species, which were then tested for resistance to ceftriaxone, colistin, and meropenem. The prevalence of ceftriaxone-resistant E. coli and Klebsiella species in pigs, chickens, rodents, pig farmers, chicken farmers, and non-farmers was 64.3%, 12.9%, 4.1%, 55.1%, 38.7%, and 36.1%, respectively. Colistin resistance in pigs, chickens, rodents, pig farmers, chicken farmers, and non-farmers was 41.3%, 9.8%, 4.6%, 34.8%, 31.6%, and 24.6%, respectively. Meropenem resistance was not detected. The observed high prevalence of AMR, especially colistin resistance, in study food animals/humans is worrisome. Further studies to identify factors that contribute to AMR, strengthened reinforcement of existing regulations on antimicrobial use, and more appropriate interventions to minimize AMR in communities are urgently needed.