Virus MIP-composites for SARS-CoV-2 detection in the aquatic environment
Issued Date
2022-05-15
Resource Type
ISSN
0167577X
eISSN
18734979
Scopus ID
2-s2.0-85125471005
Journal Title
Materials Letters
Volume
315
Rights Holder(s)
SCOPUS
Bibliographic Citation
Materials Letters Vol.315 (2022)
Suggested Citation
Sukjee W., Thitithanyanont A., Manopwisedjaroen S., Seetaha S., Thepparit C., Sangma C. Virus MIP-composites for SARS-CoV-2 detection in the aquatic environment. Materials Letters Vol.315 (2022). doi:10.1016/j.matlet.2022.131973 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/84597
Title
Virus MIP-composites for SARS-CoV-2 detection in the aquatic environment
Author's Affiliation
Other Contributor(s)
Abstract
SARS-CoV-2 is the virus responsible for causing the global COVID-19 pandemic. Identifying the presence of this virus in the environment could potentially improve the effectiveness of disease control measures. Environmental SARS-CoV-2 monitoring may become increasingly demanded in areas where the available testing methods are ineffective. In this study, we present an electrochemical polymer composites biosensor for measuring SARS-CoV-2 whole-virus particles in the environment. The sensitized layer was prepared from molecularly imprinted polymer (MIP) composites of inactivated SARS-CoV-2. Testing demonstrated increased sensor signaling with SARS-CoV-2 specifically, while lower responses were observed to the negative controls, H5N1 influenza A virus and non-imprinted polymers (NIPs). This sensor detected SARS-CoV-2 at concentrations as low as 0.1 fM in buffer and samples prepared from reservoir water with a 3 log-scale linearity.