Isolation and Antimicrobial Susceptibility Testing of Haemophilus influenzae in a Tertiary Care Hospital, a 6-Year Study (2016 to 2021)
Issued Date
2022-04-01
Resource Type
ISSN
01252208
Scopus ID
2-s2.0-85128446867
Journal Title
Journal of the Medical Association of Thailand
Volume
105
Issue
4
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of the Medical Association of Thailand Vol.105 No.4 (2022)
Suggested Citation
Chongtrakool P., Choochur P., Thuncharoon H., Srifuengfung M., Sawatdijaroongrat B., Pummangura C., Samretwit D., Srifuengfung S. Isolation and Antimicrobial Susceptibility Testing of Haemophilus influenzae in a Tertiary Care Hospital, a 6-Year Study (2016 to 2021). Journal of the Medical Association of Thailand Vol.105 No.4 (2022). doi:10.35755/jmedassocthai.2022.04.13296 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/85980
Title
Isolation and Antimicrobial Susceptibility Testing of Haemophilus influenzae in a Tertiary Care Hospital, a 6-Year Study (2016 to 2021)
Author's Affiliation
Other Contributor(s)
Abstract
Objective: To determine the prevalence and antimicrobial susceptibility of Haemophilus influenzae at Taksin Hospital. Materials and Methods: The susceptibilities of clinical isolates to six antimicrobial agents, ampicillin (AP), cefuroxime (CXM), cefotaxime (CTX), ciprofloxacin (CIP), trimethoprim-sulfamethoxazole (SXT), and meropenem (MEM), between 2016 and 2021 were evaluated by the standard disk diffusion method. Results: One hundred thirty-eight H. influenzae clinical isolates were found in different patients. There were 63.04% male patients. The ages of patients ranged from two months to 93 years old (mean±SD: 65.67±20.58). H. influenzae was mostly found in patients older than 50 (60.14%) years old. In children, H. influenzae was mostly found in patients younger than 1 to 10 (16.67%) years old. Unduplicated H. influenzae from different patients were isolated from the sputum (71.01%), blood (11.59%), pus from eyes (10.14%), and urethra (2.90%). H. influenzae demonstrated 100% susceptibility to CTX, CIP, and MEM, but less susceptibility to CXM (93.48%), AP (49.28%), and SXT (53.62%). Conclusion: The present study results suggested the importance of monitoring the prevalence of H. influenzae at a hospital in Bangkok. The antibiogram of susceptibility helps provide guidelines for clinician to consider empirical treatment.