Sural-sparing pattern: A study against electrodiagnostic subtypes of Guillain–Barre syndrome
Issued Date
2022-01-01
Resource Type
ISSN
2467981X
Scopus ID
2-s2.0-85139301415
Journal Title
Clinical Neurophysiology Practice
Volume
7
Start Page
266
End Page
272
Rights Holder(s)
SCOPUS
Bibliographic Citation
Clinical Neurophysiology Practice Vol.7 (2022) , 266-272
Suggested Citation
Pasutharnchat N. Sural-sparing pattern: A study against electrodiagnostic subtypes of Guillain–Barre syndrome. Clinical Neurophysiology Practice Vol.7 (2022) , 266-272. 272. doi:10.1016/j.cnp.2022.09.001 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/86281
Title
Sural-sparing pattern: A study against electrodiagnostic subtypes of Guillain–Barre syndrome
Author(s)
Other Contributor(s)
Abstract
Objective: To study sural-sparing pattern in Guillain–Barre syndrome (GBS) and compare it among GBS's electrodiagnostic subtypes, classified by two recent criteria. Methods: This study retrospectively reviewed clinical data and electrodiagnostic studies (EDXs) of 88 GBS patients diagnosed in a tertiary care hospital (2010–2019). Results: Overall, 79/88 (89.8%) and 36/45 (80%) patients had bilateral sensory nerve conduction studies (NCS) in the first EDX and follow-up EDX, respectively. Sural-sparing occurred in all subtypes (50% overall occurrence rate), most commonly in demyelination. There was no statistically significant difference in sural-sparing occurrence rates between demyelinating and axonal GBS; however, sural-sparing in axonal GBS tended to show a lower number of abnormal upper-limb sensory nerve action potentials (SNAPs) than demyelinating GBS. Shifting between sural-sparing and no sural-sparing occurred in approximately-one-fourth of patients receiving serial studies. Follow-up EDX additionally discovered 20% of all sural-sparing. Unilateral EDX could have omitted up to 30% of sural-sparing. Conclusions: Sural-sparing is less obviously manifested in axonal than demyelinating GBS, with respect to the number of affected upper-limb SNAPs. Extended sensory NCS is worth in detecting sural-sparing as a supportive electrodiagnostic GBS feature. Significance: This report showed one different character of sural-sparing (number of affected upper-limb SNAPs) between demyelinating and axonal GBS.