Curcuminoid extraction from rhizomes of Curcuma longa via aqueous two phases system
Issued Date
2023-01-01
Resource Type
ISSN
00986445
eISSN
15635201
Scopus ID
2-s2.0-85170576795
Journal Title
Chemical Engineering Communications
Rights Holder(s)
SCOPUS
Bibliographic Citation
Chemical Engineering Communications (2023)
Suggested Citation
Kasemwattanarot P., Kunthakudee N., Chutvirasakul B., Ramakul P. Curcuminoid extraction from rhizomes of Curcuma longa via aqueous two phases system. Chemical Engineering Communications (2023). doi:10.1080/00986445.2023.2253159 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/90063
Title
Curcuminoid extraction from rhizomes of Curcuma longa via aqueous two phases system
Author's Affiliation
Other Contributor(s)
Abstract
The extraction of curcuminoids [curcumin (C21H20O6, CUR), demethoxycurcumin (C20H18O5, DMC), and bisdemethoxycurcumin (C19H16O4, BDMC)] from Curcuma longa rhizomes was investigated using an aqueous two-phase system (ATPS) with ethanol/salt. The optimized conditions for the extraction process were determined by a central composite design to be an ethanol concentration of 13.6%, an ammonium sulfate concentration of 33.2%, and a temperature of 66.8 °C. Under these conditions, the highest yield of 97.9% was achieved, accompanied by a notable antioxidant activity of 84.38%. The experimental data exhibited good agreement with a second-order kinetic model, as confirmed by the evaluation of the coefficient of determination (R 2), normalized standard deviation, and average relative error.