ent-Clavilactone J and Its Quinone Derivative, Meroterpenoids from the Fungus Resupinatus sp.
| dc.contributor.author | Harms K. | |
| dc.contributor.author | Paomephan P. | |
| dc.contributor.author | Boonpratuang T. | |
| dc.contributor.author | Choeyklin R. | |
| dc.contributor.author | Boonchird C. | |
| dc.contributor.author | Surup F. | |
| dc.contributor.other | Mahidol University | |
| dc.date.accessioned | 2023-12-11T18:01:34Z | |
| dc.date.available | 2023-12-11T18:01:34Z | |
| dc.date.issued | 2023-01-01 | |
| dc.description.abstract | Metabolites 1 and 2, isolated from cultures of the basidiomycete Resupinatus sp. BCC84615, collected in a tropical forest in northeastern Thailand, showed weak antibiotic activity against Bacillus subtilis and Staphylococcus aureus and cytotoxicity against cancer cell lines. Their planar structures were elucidated by high-resolution electrospray ionization mass spectrometry and NMR spectroscopy as clavilactone J, known from the basidiomycete Ampulloclitocybe clavipes, and its new 1,4-benzoquinone derivative. A detailed analysis of the ROESY correlations in 1 confirmed the recent revision of the relative configuration of clavilactone J. However, specific rotation and Cotton effects observed by electronic circular dichroism were contrary to those of the clavilactones; thus, we assigned a rare antipodal absolute configuration. | |
| dc.identifier.citation | Journal of Natural Products (2023) | |
| dc.identifier.doi | 10.1021/acs.jnatprod.3c00174 | |
| dc.identifier.eissn | 15206025 | |
| dc.identifier.issn | 01633864 | |
| dc.identifier.pmid | 37931226 | |
| dc.identifier.scopus | 2-s2.0-85178247603 | |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/91395 | |
| dc.rights.holder | SCOPUS | |
| dc.subject | Chemistry | |
| dc.title | ent-Clavilactone J and Its Quinone Derivative, Meroterpenoids from the Fungus Resupinatus sp. | |
| dc.type | Article | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85178247603&origin=inward | |
| oaire.citation.title | Journal of Natural Products | |
| oairecerif.author.affiliation | Mahidol University | |
| oairecerif.author.affiliation | Helmholtz Centre for Infection Research (HZI) | |
| oairecerif.author.affiliation | Technische Universität Braunschweig | |
| oairecerif.author.affiliation | Thailand National Science and Technology Development Agency | |
| oairecerif.author.affiliation | Biodiversity-Based Economy Development Office (Public Organization) |