Electrochemical trifluoromethylation of 2-isocyanobiaryls using CF<inf>3</inf>SO<inf>2</inf>Na: synthesis of 6-(trifluoromethyl)phenanthridines
| dc.contributor.author | La-Ongthong K. | |
| dc.contributor.author | Chantarojsiri T. | |
| dc.contributor.author | Soorukram D. | |
| dc.contributor.author | Leowanawat P. | |
| dc.contributor.author | Reutrakul V. | |
| dc.contributor.author | Kuhakarn C. | |
| dc.contributor.other | Mahidol University | |
| dc.date.accessioned | 2023-05-19T08:06:10Z | |
| dc.date.available | 2023-05-19T08:06:10Z | |
| dc.date.issued | 2023-01-01 | |
| dc.description.abstract | An efficient trifluoromethylation of 2-isocyanobiaryls was developed through the constant current electrolysis, employing sodium trifluoromethanesulfinate (CF3SO2Na) as the trifluoromethyl source. The method enabled the syntheses of a series of 6-(trifluoromethyl)phenanthridine derivatives in moderate to high yields under metal- and oxidant-free conditions. A gram-scale synthesis highlights the synthetic versatility of the reported protocol. | |
| dc.identifier.citation | Organic and Biomolecular Chemistry (2023) | |
| dc.identifier.doi | 10.1039/d3ob00239j | |
| dc.identifier.issn | 14770520 | |
| dc.identifier.scopus | 2-s2.0-85149893302 | |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/82325 | |
| dc.rights.holder | SCOPUS | |
| dc.subject | Biochemistry, Genetics and Molecular Biology | |
| dc.title | Electrochemical trifluoromethylation of 2-isocyanobiaryls using CF<inf>3</inf>SO<inf>2</inf>Na: synthesis of 6-(trifluoromethyl)phenanthridines | |
| dc.type | Article | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85149893302&origin=inward | |
| oaire.citation.title | Organic and Biomolecular Chemistry | |
| oairecerif.author.affiliation | Mahidol University |