Gut microbiota-associated metabolites in metabolic diseases and their impact from food processing
1
Issued Date
2024-01-01
Resource Type
eISSN
2836774X
Scopus ID
2-s2.0-85213802757
Journal Title
Food Innovation and Advances
Volume
3
Issue
4
Start Page
438
End Page
448
Rights Holder(s)
SCOPUS
Bibliographic Citation
Food Innovation and Advances Vol.3 No.4 (2024) , 438-448
Suggested Citation
Huang A., Wu Q., Thanuphol P., da Cruz L.L., Xie Z., Chen M., Zhang F., Zhu Z., Ding Y. Gut microbiota-associated metabolites in metabolic diseases and their impact from food processing. Food Innovation and Advances Vol.3 No.4 (2024) , 438-448. 448. doi:10.48130/fia-0024-0038 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/102661
Title
Gut microbiota-associated metabolites in metabolic diseases and their impact from food processing
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Corresponding Author(s)
Other Contributor(s)
Abstract
Gut microbiota-associated metabolites can be synthesized endogenously or derived from dietary nutrients and host compounds. Among them, alkaloids, terpenes, and flavones originating from edible and medicinal foods have attracted remarkable interest recently and play crucial roles in metabolic diseases. The efficacy of these metabolites is susceptible to dietary intervention, especially after food processing. Therefore, this review comprehensively summarizes the different sources of common gut microbial metabolites, including microbial self-synthesis, biodegradation of exogenous substances (mainly dietary nutrients), and participation in host metabolism. In addition, the latest studies on novel metabolites such as alkaloids, terpenoids, and flavonoids are discussed, and their action mechanisms on metabolic diseases are elaborated. How food processing impacts dietary nutrients and their metabolites is carefully examined, as well as their effects on disease modification. These insights could contribute to a deeper understanding of the mechanisms by which diet efficacy helps prevent metabolic diseases, particularly through gut microbial metabolites.