Gut microbiota-associated metabolites in metabolic diseases and their impact from food processing

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dc.contributor.authorHuang A.
dc.contributor.authorWu Q.
dc.contributor.authorThanuphol P.
dc.contributor.authorda Cruz L.L.
dc.contributor.authorXie Z.
dc.contributor.authorChen M.
dc.contributor.authorZhang F.
dc.contributor.authorZhu Z.
dc.contributor.authorDing Y.
dc.contributor.correspondenceHuang A.
dc.contributor.otherMahidol University
dc.date.accessioned2025-01-10T18:05:17Z
dc.date.available2025-01-10T18:05:17Z
dc.date.issued2024-01-01
dc.description.abstractGut microbiota-associated metabolites can be synthesized endogenously or derived from dietary nutrients and host compounds. Among them, alkaloids, terpenes, and flavones originating from edible and medicinal foods have attracted remarkable interest recently and play crucial roles in metabolic diseases. The efficacy of these metabolites is susceptible to dietary intervention, especially after food processing. Therefore, this review comprehensively summarizes the different sources of common gut microbial metabolites, including microbial self-synthesis, biodegradation of exogenous substances (mainly dietary nutrients), and participation in host metabolism. In addition, the latest studies on novel metabolites such as alkaloids, terpenoids, and flavonoids are discussed, and their action mechanisms on metabolic diseases are elaborated. How food processing impacts dietary nutrients and their metabolites is carefully examined, as well as their effects on disease modification. These insights could contribute to a deeper understanding of the mechanisms by which diet efficacy helps prevent metabolic diseases, particularly through gut microbial metabolites.
dc.identifier.citationFood Innovation and Advances Vol.3 No.4 (2024) , 438-448
dc.identifier.doi10.48130/fia-0024-0038
dc.identifier.eissn2836774X
dc.identifier.scopus2-s2.0-85213802757
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/102661
dc.rights.holderSCOPUS
dc.subjectAgricultural and Biological Sciences
dc.titleGut microbiota-associated metabolites in metabolic diseases and their impact from food processing
dc.typeReview
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85213802757&origin=inward
oaire.citation.endPage448
oaire.citation.issue4
oaire.citation.startPage438
oaire.citation.titleFood Innovation and Advances
oaire.citation.volume3
oairecerif.author.affiliationInstitute of Microbiology, Guangdong Academy of Sciences
oairecerif.author.affiliationUniversidade Estacio de Sa
oairecerif.author.affiliationJinan University
oairecerif.author.affiliationMahidol University
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