Methodology for the Development of the Allergic Rhinitis and Its Impact on Asthma (ARIA)-EAACI 2024–2025 Guidelines: From Evidence-to-Decision Frameworks to Digitalised Shared Decision-Making Algorithms

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dc.contributor.authorBousquet J.
dc.contributor.authorSousa-Pinto B.
dc.contributor.authorVieira R.J.
dc.contributor.authorSchünemann H.J.
dc.contributor.authorZuberbier T.
dc.contributor.authorBognanni A.
dc.contributor.authorTogias A.
dc.contributor.authorSamolinski B.
dc.contributor.authorValiulis A.
dc.contributor.authorWilliams S.
dc.contributor.authorBedbrook A.
dc.contributor.authorCzarlewski W.
dc.contributor.authorTorres M.J.
dc.contributor.authorShamji M.H.
dc.contributor.authorMorais-Almeida M.
dc.contributor.authorCanonica G.W.
dc.contributor.authorVecillas L.d.l.
dc.contributor.authorDykewicz M.S.
dc.contributor.authorJacomelli C.
dc.contributor.authorKlimek L.
dc.contributor.authorLeemann L.
dc.contributor.authorLourenço O.
dc.contributor.authorPalamarchuk Y.
dc.contributor.authorPapadopoulos N.G.
dc.contributor.authorPereira A.M.
dc.contributor.authorSavouré M.
dc.contributor.authorToppila-Salmi S.K.
dc.contributor.authorVentura M.T.
dc.contributor.authorYepes-Nuñez J.J.
dc.contributor.authorCruz A.A.
dc.contributor.authorCiprandi G.
dc.contributor.authorGemicioglu B.
dc.contributor.authorGiovannini M.
dc.contributor.authorGradauskiene B.
dc.contributor.authorJartti T.
dc.contributor.authorJeseňák M.
dc.contributor.authorKuna P.
dc.contributor.authorKvedariene V.
dc.contributor.authorLarenas-Linnemann D.E.
dc.contributor.authorLatiff A.H.A.
dc.contributor.authorMohammad Y.
dc.contributor.authorOhta K.
dc.contributor.authorMahesh P.A.
dc.contributor.authorPali-Schöll I.
dc.contributor.authorPfaar O.
dc.contributor.authorRegateiro F.S.
dc.contributor.authorRoche N.
dc.contributor.authorSofiev M.
dc.contributor.authorTaborda-Barata L.
dc.contributor.authorUlrik C.S.
dc.contributor.authorRostan M.V.
dc.contributor.authorViegi G.
dc.contributor.authorZhang L.
dc.contributor.authorAntó J.M.
dc.contributor.authorHaahtela T.
dc.contributor.authorCherrez-Ojeda I.
dc.contributor.authorIvancevich J.C.
dc.contributor.authorKhaltaev N.
dc.contributor.authorYorgancioglu A.
dc.contributor.authorAbdullah B.
dc.contributor.authorAl-Ahmad M.
dc.contributor.authorAl-Nesf M.A.
dc.contributor.authorAmaral R.
dc.contributor.authorAsllani J.
dc.contributor.authorBergmann K.C.
dc.contributor.authorBernstein J.A.
dc.contributor.authorBlaiss M.S.
dc.contributor.authorBraido F.
dc.contributor.authorCamargos P.
dc.contributor.authorCarreiro-Martins P.
dc.contributor.authorCasale T.
dc.contributor.authorCecchi L.
dc.contributor.authorFiocchi A.G.
dc.contributor.authorGiuliano A.F.M.
dc.contributor.authorChristoff G.
dc.contributor.authorCirule I.
dc.contributor.authorCorreia-de-Sousa J.
dc.contributor.authorCosta E.M.
dc.contributor.authorDel Giacco S.
dc.contributor.authorDevillier P.
dc.contributor.authorDokic D.
dc.contributor.authorHossny E.
dc.contributor.authorIinuma T.
dc.contributor.authorIrani C.
dc.contributor.authorIspayeva Z.
dc.contributor.authorJulge K.
dc.contributor.authorKaidashev I.
dc.contributor.authorBennoor K.S.
dc.contributor.authorKraxner H.
dc.contributor.authorKull I.
dc.contributor.authorKulus M.
dc.contributor.authorKupczyk M.
dc.contributor.authorKurchenko A.
dc.contributor.authorLa Grutta S.
dc.contributor.authorMiculinic N.
dc.contributor.authorTuyet L.L.T.
dc.contributor.authorMakris M.
dc.contributor.authorMilenkovic B.
dc.contributor.authorLee S.M.
dc.contributor.authorMontefort S.
dc.contributor.correspondenceBousquet J.
dc.contributor.otherMahidol University
dc.date.accessioned2026-02-08T18:15:59Z
dc.date.available2026-02-08T18:15:59Z
dc.date.issued2026-02-01
dc.description.abstractThe Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines produced their first edition in 1999, with subsequent revisions in 2008, 2010, 2016 and 2019. A new iteration of ARIA—ARIA 2024–2025—in collaboration with EAACI is currently being developed, focusing on the management of allergic rhinitis. ARIA 2024–2025 follows the GRADE framework and is endorsed by the European Academy of Allergy and Clinical Immunology (EAACI). A set of approaches has been used to develop guideline questions, including surveying key opinion leaders and using artificial intelligence (AI)-based tools to analyse web searches on allergic rhinitis and to generate questions. Each prioritised guideline question is assessed through an Evidence-to-Decision (EtD) framework. EtDs support the systematic and transparent formulation of recommendations, comprising 12 criteria for which the best available evidence should be sought. In the context of ARIA-EAACI 2024–2025, such evidence is derived not only from randomised controlled trials but also—among others—from patient-generated data sources that better reflect the affected individuals' perspectives. Moreover, ARIA-EAACI 2024–2025 incorporates evidence on planetary health. Developed guideline recommendations will support the creation of digitalised decision algorithms and care pathways. This paper describes the methodology used to develop the person-centred, digitally enabled and AI-assisted ARIA-EAACI 2024–2025. Among others, it describes (i) the development and prioritisation of guideline questions, (ii) sources of evidence for EtDs and (iii) the development of digitalised decision algorithms and care pathways.
dc.identifier.citationAllergy European Journal of Allergy and Clinical Immunology Vol.81 No.2 (2026) , 427-453
dc.identifier.doi10.1111/all.70100
dc.identifier.eissn13989995
dc.identifier.issn01054538
dc.identifier.pmid41268627
dc.identifier.scopus2-s2.0-105029024197
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/123456789/114886
dc.rights.holderSCOPUS
dc.subjectMedicine
dc.subjectImmunology and Microbiology
dc.titleMethodology for the Development of the Allergic Rhinitis and Its Impact on Asthma (ARIA)-EAACI 2024–2025 Guidelines: From Evidence-to-Decision Frameworks to Digitalised Shared Decision-Making Algorithms
dc.typeArticle
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=105029024197&origin=inward
oaire.citation.endPage453
oaire.citation.issue2
oaire.citation.startPage427
oaire.citation.titleAllergy European Journal of Allergy and Clinical Immunology
oaire.citation.volume81
oairecerif.author.affiliationConsiglio Nazionale delle Ricerche
oairecerif.author.affiliationKøbenhavns Universitet
oairecerif.author.affiliationUniversité Paris-Saclay
oairecerif.author.affiliationKarolinska Institutet
oairecerif.author.affiliationUppsala Universitet
oairecerif.author.affiliationMcMaster University
oairecerif.author.affiliationUniversität Zürich
oairecerif.author.affiliationCharité – Universitätsmedizin Berlin
oairecerif.author.affiliationUniversità degli Studi di Firenze
oairecerif.author.affiliationUniversidade do Porto
oairecerif.author.affiliationAP-HP Assistance Publique - Hopitaux de Paris
oairecerif.author.affiliationNational and Kapodistrian University of Athens
oairecerif.author.affiliationUniversità degli Studi di Genova
oairecerif.author.affiliationUniversidade Federal de Minas Gerais
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oairecerif.author.affiliationChiba University
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oairecerif.author.affiliationTartu Ülikool
oairecerif.author.affiliationMedical College of Georgia
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oairecerif.author.affiliationNational Heart and Lung Institute
oairecerif.author.affiliationCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública
oairecerif.author.affiliationHumanitas Research Hospital
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oairecerif.author.affiliationUniversidade da Beira Interior
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oairecerif.author.affiliationHvidovre Hospital
oairecerif.author.affiliationL-Università ta' Malta
oairecerif.author.affiliationVeterinarmedizinische Universitat Wien
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oairecerif.author.affiliationUniversitätsklinikum Gießen und Marburg, Standort Marburg
oairecerif.author.affiliationHumanitas University
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oairecerif.author.affiliationHospital Regional Universitario Carlos Haya
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oairecerif.author.affiliationSchool of Medical Sciences, Universiti Sains Malaysia
oairecerif.author.affiliationFinnish Meteorological Institute
oairecerif.author.affiliationUniversidade de Coimbra, Faculdade de Medicina
oairecerif.author.affiliationInstituto de Salud Global de Barcelona
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oairecerif.author.affiliationSödersjukhuset
oairecerif.author.affiliationLietuvos Sveikatos Mokslų Universitetas
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oairecerif.author.affiliationNOVA Medical School - Faculdade de Ciências Médicas, Universidade Nova de Lisboa
oairecerif.author.affiliationBogomolets National Medical University
oairecerif.author.affiliationScuola di Medicina
oairecerif.author.affiliationEscola de Medicina da Universidade do Minho
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oairecerif.author.affiliationJesseniuss Faculty of Medicine
oairecerif.author.affiliationUniversidad Espíritu Santo
oairecerif.author.affiliationDankook University, College of Medicine
oairecerif.author.affiliationJSS Medical College & Hospital, Mysuru
oairecerif.author.affiliationIstituto di Scienze delle Produzioni Alimentari
oairecerif.author.affiliationFundacion Santa Fe de Bogota
oairecerif.author.affiliationAzienda Ospedaliero Universitaria di Cagliari
oairecerif.author.affiliationCentre for Innovative Biomedicine and Biotechnology
oairecerif.author.affiliationAsfendiyarov Kazakh National Medical University
oairecerif.author.affiliationPoltava State Medical University
oairecerif.author.affiliationUniversité Tichrine
oairecerif.author.affiliationFundacion Clinica Medica Sur
oairecerif.author.affiliationFraunhofer Institute for Translational Medicine and Pharmacology ITMP
oairecerif.author.affiliationEscola Superior de Saúde do Politécnico do Porto
oairecerif.author.affiliationBeijing Institute of Otorhinolaryngology
oairecerif.author.affiliationHospital de Dona Estefânia
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oairecerif.author.affiliationSkin and Allergy Hospital
oairecerif.author.affiliationFukujuji Hospital
oairecerif.author.affiliationFaculty of Health Sciences
oairecerif.author.affiliationUniwersytecki Szpital Kliniczny Nr 1 im. Norberta Barlickiego w Lodz
oairecerif.author.affiliationUniversiteti i Mjekësisë, Tiranë
oairecerif.author.affiliationUniversidad de Los Andes, Facultad de Medicina
oairecerif.author.affiliationBērnu klīniskā UniversItātes Slimnīca
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oairecerif.author.affiliationAin Shams University Children's Hospital
oairecerif.author.affiliationUSL Toscana Centro
oairecerif.author.affiliationClinica Santa Isabel
oairecerif.author.affiliationCenter for Rhinology and Allergology
oairecerif.author.affiliationMeyer Children's Hospital IRCCS
oairecerif.author.affiliationAl-Sham Private University
oairecerif.author.affiliationHospital CUF Descobertas
oairecerif.author.affiliationCova da Beira University Hospital Centre
oairecerif.author.affiliationUniversity Medical Center
oairecerif.author.affiliationNational Institute of Diseases of the Chest and Hospital
oairecerif.author.affiliationMedical Consulting Czarlewski
oairecerif.author.affiliationUniversity Teaching Hospital in Martin
oairecerif.author.affiliationCroatian Pulmonary Society
oairecerif.author.affiliationInstituto and Hospital CUF
oairecerif.author.affiliationInternational Primary Care Respiratory Group
oairecerif.author.affiliationAllergic Rhinitis and its Impact on Asthma
oairecerif.author.affiliationRespiralab Research Group
oairecerif.author.affiliationUniversity Clinic of Pulmonology and Allergy
oairecerif.author.affiliationAllergy
oairecerif.author.affiliationLatín American Society of Allergy
oairecerif.author.affiliationAllergology Department
oairecerif.author.affiliationPatients’ Association “Respiriamo insieme”
oairecerif.author.affiliationGlobal NCD Platform

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