Food choices and body weight changes: A mathematical model analysis
Issued Date
2025-01-01
Resource Type
ISSN
15471063
eISSN
15510018
Scopus ID
2-s2.0-105008039871
Journal Title
Mathematical Biosciences and Engineering
Volume
22
Issue
7
Start Page
1790
End Page
1824
Rights Holder(s)
SCOPUS
Bibliographic Citation
Mathematical Biosciences and Engineering Vol.22 No.7 (2025) , 1790-1824
Suggested Citation
Chudtong M., De Gaetano A. Food choices and body weight changes: A mathematical model analysis. Mathematical Biosciences and Engineering Vol.22 No.7 (2025) , 1790-1824. 1824. doi:10.3934/mbe.2025065 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/110833
Title
Food choices and body weight changes: A mathematical model analysis
Author(s)
Corresponding Author(s)
Other Contributor(s)
Abstract
A short–term stochastic model of minute–by–minute food intake is formulated, incorporating the interaction of appetite, insulinemia, and glycemia in determining the size and frequency of meals. By assuming a person would maintain his or her eating habit over time, we extend the simulation period to several years and explore scenarios based on food choices (high–fiber vs. high–carbohydrate) or appetite suppression. The model coherently predicts increments or decrements in body weight in the long–term when altering appetite in the short–term. Further, the model shows how food type choice, at the same appetite drive and habitual proposed meal size, induces macroscopic changes in body weight over a very few years. The model is innovative in that it connects the minute–by–minute behavior of the individual with long–term changes in metabolic compensation, in insulin sensitivity, in glycemic variability, and eventually in body size, thus helping to interpret the long–term development of Type 2 diabetes mellitus resulting from an unhealthy lifestyle.