Using Deep Learning to Segment Retinal Vascular Leakage and Occlusion in Retinal Vasculitis
1
Issued Date
2024-01-01
Resource Type
ISSN
09273948
eISSN
17445078
Scopus ID
2-s2.0-85183009552
Journal Title
Ocular Immunology and Inflammation
Rights Holder(s)
SCOPUS
Bibliographic Citation
Ocular Immunology and Inflammation (2024)
Suggested Citation
Dhirachaikulpanich D., Xie J., Chen X., Li X., Madhusudhan S., Zheng Y., Beare N.A.V. Using Deep Learning to Segment Retinal Vascular Leakage and Occlusion in Retinal Vasculitis. Ocular Immunology and Inflammation (2024). doi:10.1080/09273948.2024.2305185 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/95784
Title
Using Deep Learning to Segment Retinal Vascular Leakage and Occlusion in Retinal Vasculitis
Corresponding Author(s)
Other Contributor(s)
Abstract
Purpose: Retinal vasculitis (RV) is characterised by retinal vascular leakage, occlusion or both on fluorescein angiography (FA). There is no standard scheme available to segment RV features. We aimed to develop a deep learning model to segment both vascular leakage and occlusion in RV. Methods: Four hundred and sixty-three FA images from 82 patients with retinal vasculitis were used to develop a deep learning model, in 60:20:20 ratio for training:validation:testing. Parameters, including deep learning architectures (DeeplabV3+, UNet++ and UNet), were altered to find the best binary segmentation model separately for retinal vascular leakage and occlusion, using a Dice score to determine the reliability of each model. Results: Our best model for vascular leakage had a Dice score of 0.6279 (95% confidence interval (CI) 0.5584–0.6974). For occlusion, the best model achieved a Dice score of 0.6992 (95% CI 0.6109–0.7874). Conclusion: Our RV segmentation models could perform reliable segmentation for retinal vascular leakage and occlusion in FAs of RV patients.