Antiparasitic effect of peptoids against Cryptosporidium parvum
Issued Date
2025-10-01
Resource Type
eISSN
14652080
Scopus ID
2-s2.0-105018527741
Pubmed ID
41082282
Journal Title
Microbiology Reading England
Volume
171
Issue
10
Rights Holder(s)
SCOPUS
Bibliographic Citation
Microbiology Reading England Vol.171 No.10 (2025)
Suggested Citation
Lamont B., Russell B.M., Suwanarusk R., Nielsen J.E., Sørensen K., Yung D., Barron A.E., Pletzer D., Muhsin-Sharafaldine M.R. Antiparasitic effect of peptoids against Cryptosporidium parvum. Microbiology Reading England Vol.171 No.10 (2025). doi:10.1099/mic.0.001607 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/112667
Title
Antiparasitic effect of peptoids against Cryptosporidium parvum
Author's Affiliation
Corresponding Author(s)
Other Contributor(s)
Abstract
Cryptosporidiosis, caused by Cryptosporidium parvum, poses significant health risks, particularly for children and immunocompromised individuals. Current treatments are ineffective in these vulnerable groups. This study explores the antiparasitic effects of peptoids against C. parvum. Out of 14 synthetic peptidomimetics (peptoids) screened, TM9 and TM19 exhibited potent anti-cryptosporidial activity with minimal host toxicity. These findings suggest that peptoids could be a promising new therapeutic avenue for cryptosporidiosis, warranting further investigation.