Screening for phytochemicals and free radical scavenging activity of Vitex glabrata R.Br. fruit extract
Issued Date
2019
Resource Type
Language
eng
Rights
Mahidol University
Rights Holder(s)
Faculty of Pharmacy Mahidol University
Suggested Citation
Pornsak Laokijpaisal, Penchom Peungvicha, Nakkawee Saengklub, Supachoke Mangmool, Nutputsorn Chatsumpun, เพ็ญโฉม พึ่งวิชา, นรรฆวี แสงกลับ, ศุภโชค มั่งมูล, นัฏฐ์ภัสสร ชาติสัมปันน์ (2019). Screening for phytochemicals and free radical scavenging activity of Vitex glabrata R.Br. fruit extract. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/52393
Title
Screening for phytochemicals and free radical scavenging activity of Vitex glabrata R.Br. fruit extract
Abstract
Thai folk healers have claimed that ripe fruits of Vitex glabrata (Vg) are a remedy of
malnutrition treatment usually associated with intestinal parasitism in children, diabetes,
nephron tonic and erectile dysfunction. However, there is no scientific evidence support. The
aim of this study is to investigate the phytochemical screening and free radical scavenging
activity of the EtOH extract of Vg ripe fruits. The polyphenols, tannins, coumarins, triterpenes,
and unsaturated lactone rings compounds were detected in EtOH Vg extract. The total phenolic
content in the extract was 36.04±0.12 mg of GAE/g of dry plant material determined by Folin-
Ciocalteu method. The DPPH assay showed that the extract had free radical scavenging
activity, the IC50 was 346.64±4.48 μg/mL. The thin-layer chromatography (TLC) system was
developed using chloroform: acetic acid (85:15) as a solvent system, the TLC chromatogram
might be used as plant fingerprint in the future study.
Description
The 1st Pharmaceutical Sciences Asia Conference 2019 Theme : Pharmaceutical Sciences toward Health Innovation in the Disruptive Era. Bangkok Midtown Hotel, Thailand. August 22, 2019, page 64-69
