Screening for phytochemicals and free radical scavenging activity of Vitex glabrata R.Br. fruit extract

dc.contributor.authorPornsak Laokijpaisalen_US
dc.contributor.authorPenchom Peungvichaen_US
dc.contributor.authorNakkawee Saengkluben_US
dc.contributor.authorSupachoke Mangmoolen_US
dc.contributor.authorNutputsorn Chatsumpunen_US
dc.contributor.authorเพ็ญโฉม พึ่งวิชาen_US
dc.contributor.authorนรรฆวี แสงกลับen_US
dc.contributor.authorศุภโชค มั่งมูลen_US
dc.contributor.authorนัฏฐ์ภัสสร ชาติสัมปันน์en_US
dc.contributor.otherMahidol University. Faculty of Pharmacy. Department of Physiology,en_US
dc.contributor.otherMahidol University. Faculty of Pharmacy. Department of Pharmacologyen_US
dc.contributor.otherMahidol University. Faculty of Pharmacy. Department of Pharmacognosyen_US
dc.date.accessioned2020-01-28T08:30:47Z
dc.date.available2020-01-28T08:30:47Z
dc.date.created2020-01-28
dc.date.issued2019
dc.descriptionThe 1st Pharmaceutical Sciences Asia Conference 2019 Theme : Pharmaceutical Sciences toward Health Innovation in the Disruptive Era. Bangkok Midtown Hotel, Thailand. August 22, 2019, page 64-69en_US
dc.description.abstractThai folk healers have claimed that ripe fruits of Vitex glabrata (Vg) are a remedy of malnutrition treatment usually associated with intestinal parasitism in children, diabetes, nephron tonic and erectile dysfunction. However, there is no scientific evidence support. The aim of this study is to investigate the phytochemical screening and free radical scavenging activity of the EtOH extract of Vg ripe fruits. The polyphenols, tannins, coumarins, triterpenes, and unsaturated lactone rings compounds were detected in EtOH Vg extract. The total phenolic content in the extract was 36.04±0.12 mg of GAE/g of dry plant material determined by Folin- Ciocalteu method. The DPPH assay showed that the extract had free radical scavenging activity, the IC50 was 346.64±4.48 μg/mL. The thin-layer chromatography (TLC) system was developed using chloroform: acetic acid (85:15) as a solvent system, the TLC chromatogram might be used as plant fingerprint in the future study.en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/52393
dc.language.isoengen_US
dc.rightsMahidol Universityen_US
dc.rights.holderFaculty of Pharmacy Mahidol Universityen_US
dc.subjectVitex glabrata (Vg)en_US
dc.subjectfruiten_US
dc.subjectPhytochemicalsen_US
dc.subjectfruit extracten_US
dc.titleScreening for phytochemicals and free radical scavenging activity of Vitex glabrata R.Br. fruit extracten_US
dc.typeProceeding Articleen_US

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