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Now showing 1 - 10 of 11
  • Publication
    Biomagnetic of Apatite-Coated Cobalt Ferrite: A Core-Shell Particle for Protein Adsorption and pH-Controlled Release
    (2011-01-01) I. Ming Tang; Nateetip Krishnamra; Narattaphol Charoenphandhu; Rassmidara Hoonsawat; Weeraphat Pon-On; Commission of Higher Education; Mahidol University
    Magnetic nanoparticle composite with a cobalt ferrite (CoFe 2 O 4 , (CF)) core and an apatite (Ap) coating was synthesized using a biomineralization process in which a modified simulated body fluid (1.5SBF) solution is the source of the calcium... phosphate for the apatite formation. The core-shell structure formed after the citric acid-stabilized cobalt ferrite (CFCA) particles were incubated in the 1.5 SBF solution for 1 week. The mean particle size of CFCA-Ap is about 750 nm. A saturation
  • Publication
    Biomagnetic of apatite-coated cobalt ferrite: A core-shell particle for protein adsorption and pH-controlled release
    (2012-01-26) I. Ming Tang; Nateetip Krishnamra; Narattaphol Charoenphandhu; Rassmidara Hoonsawat; Weeraphat Pon-On; Commission of Higher Education; Mahidol University
    Magnetic nanoparticle composite with a cobalt ferrite (CoFe 2 O 4 , (CF)) core and an apatite (Ap) coating was synthesized using a biomineralization process in which a modified simulated body fluid (1.5SBF) solution is the source of the calcium... phosphate for the apatite formation. The core-shell structure formed after the citric acid- stabilized cobalt ferrite (CFCA) particles were incubated in the 1.5 SBF solution for 1 week. The mean particle size of CFCA-Ap is about 750 nm. A saturation
  • Publication
    Synthesis and investigations of mineral ions-loaded apatite from fish scale and PLA/chitosan composite for bone scaffolds
    (2018-06-15) Weeraphat Pon-On; Panan Suntornsaratoon; Narattaphol Charoenphandhu; Jirawan Thongbunchoo; Nateetip Krishnamra; I. Ming Tang; King Mongkuts University of Technology; Kasetsart University; Mahidol University
    © 2018 In this study, composite scaffolds consisting of mineral ion-loaded hydroxyapatite derived from fish scale (mHAFS) in a poly(lactic acid) (PLA)/chitosan (Chi) matrix (mHAFS@PLAChi) were fabricated by an in situ blending technique. Mineral ion loaded HAFS was successfully converted into mHAFS via the hydrothermal heating of HAFS in a SBF (simulated body fluid) solution. The composite mHAFS with PLAChi showed a compressive strength of 20 MPa and a compressive modulus of 539.88 MPa with a microporous structure. In vitro investigation showed that the UMR-106 cells adhered well and proliferated on the mHAFS@PLAChi surface. Most importantly it improved the cell viability and alkaline phosphate (ALP) activity. These findings suggest that these synthesized materials have great potential for use in bone tissue engineering.
  • Publication
    In vitro study of the SBF and osteoblast-like cells on hydroxyapatite/ chitosan-silica nanocomposite
    (2011-03-12) Prapaporn Jongwattanapisan; Narattaphol Charoenphandhu; Nateetip Krishnamra; Jirawan Thongbunchoo; I. Ming Tang; Rassmidara Hoonsawat; Siwaporn Meejoo Smith; Weeraphat Pon-On; Mahidol University; Commission on Higher Education
    with calcium phosphate (CaP) which is desirable for the formation of the apatite. XRD and TEM studies showed that the HAp formed in the CSi matrix were nanometer (20-40 nm) in size. Nanocomposites of HApCSi20 processed with 20%v/v silica whisker showed a micro... hardness of 84.7 ± 3.3 MPa. Mineralization study in SBF showed the formation of apatite crystals on the HApCSi surface after being incubated for 7 days. In vitro biocompatibility, cell morphology, proliferation, and cell adhesion tests confirmed
  • Publication
    In vitro study of the SBFand osteoblast-like cells on hydroxyapatite/chitosan–silica nanocomposite
    (2011) Prapaporn Jongwattanapisan; Narattaphol Charoenphandhu; Nateetip Krishnamra; Jirawan Thongbunchoo; I-Ming Tang; Rassmidara Hoonsawat; Siwaporn Meejoo Smith; Weeraphat Pon-On; Mahidol University. Mahidol University International College. Science Division.
    with calcium phosphate (CaP) which is desirable for the formation of the apatite. XRD and TEM studies showed that the HAp formed in the CSi matrix were nanometer (20-40 nm) in size. anocomposites of HApCSi20 processed with 20%v/v silica whisker showed a micro... hardness of 84.7 ± 3.3 MPa. Mineralization study in SBF showed the formation of apatite crystals on the HApCSi surface after being incubated for 7 days. In vitro biocompatibility, cell morphology, proliferation, and cell adhesion tests confirmed
  • Publication
    Biocomposite of hydroxyapatite-titania rods (HApTiR): Physical properties and in vitro study
    (2013-01-01) Weeraphat Pon-On; Narattaphol Charoenphandhu; I. Ming Tang; Jarinthorn Teerapornpuntakit; Jirawan Thongbunchoo; Nateetip Krishnamra; Kasetsart University; Mahidol University; Commission of Higher Education
    showed a core-shell structure with the titania rod as the core and the apatite as the shell. The hardness of the composites of HApTiR's whisker increased from 74.8 to 92.9 MPa as the TiR content was increased from 10 to 90 wt.%. Mineralization study... in SBF showed the formation of apatite crystals on the HApTiR's surface after 7 days of incubation. In vitro cell adhesion tests confirmed the osteoblast attachment and growth on the HApTiR's surface. The density of cells, spread and the production
  • Publication
    Physicochemical and biochemical properties of iron-loaded silicon substituted hydroxyapatite (FeSiHAp)
    (2013-09-16) Weeraphat Pon-On; Narattaphol Charoenphandhu; Jarinthorn Teerapornpuntakit; Jirawan Thongbunchoo; Nateetip Krishnamra; I. Ming Tang; Kasetsart University; Mahidol University; Commission of Higher Education
    . The synthesized powders still exhibited the apatite structure for iron contents up to x = 0.5. The surface charge became less negative, from -21.3 to -13.5 mV as the iron loading was increased. Compounds of FeSiHAp whisker showed a micro hardness in rang of 80-84... to the release from the non iron loaded particles. Mineralization study showed the formation of apatite crystals on the FeSiHAp surface after modified simulated body fluid (m-SBF) incubation. In vitro cell growth on the FeSiHAp surface, the density of cells
  • Publication
    Hydroxyapatite from fish scale for potential use as bone scaffold or regenerative material
    (2016-05-01) Weeraphat Pon-On; Panan Suntornsaratoon; Narattaphol Charoenphandhu; Jirawan Thongbunchoo; Nateetip Krishnamra; I. Ming Tang; Kasetsart University; Mahidol University
    ) is 2.01 (Ca-rich CaP). Whereas, synthesized HA consists of sub-micron HA particle having a Ca/P ratio of 1.65. Bioactivity test shows that the FSHA forms more new apatite than does the sHA after being incubated in simulated body fluid (SBF) for 7 days
  • Publication
    Mechanical properties, biological activity and protein controlled release by poly(vinyl alcohol)-bioglass/chitosan-collagen composite scaffolds: A bone tissue engineering applications
    (2014-05-01) Weeraphat Pon-On; Narattaphol Charoenphandhu; Jarinthorn Teerapornpuntakit; Jirawan Thongbunchoo; Nateetip Krishnamra; I. Ming Tang; Kasetsart University; Mahidol University; Commission of Higher Education
    :ChiCol. Mineralization study in SBF showed the formation of apatite crystals on the PVABG:ChiCol surface after 7 days of incubation. In vitro cell availability and proliferation tests confirmed the osteoblast attachment and growth on the PVABG:ChiCol surface. MTT and ALP
  • Publication
    Fabrication of biocomposite scaffolds made with modified hydroxyapatite inclusion of chitosan-grafted-poly(methyl methacrylate) for bone tissue engineering
    (2019-03-01) Tanatsaparn Tithito; Panan Suntornsaratoon; Narattaphol Charoenphandhu; Jirawan Thongbunchoo; Nateetip Krishnamra; I. Ming Tang; Weeraphat Pon-On; Kasetsart University; Mahidol University; King Mongkut s University of Technology Thonburi; Academy of Science
    . In bioactivity studies, more apatite formation on the surface were seen after immersion in the SBF solution. In vitro growth experiments using UMR-106 osteoblast-like cells on the mHA@Chi-g-PMMA scaffold case showed that the attachment, viability