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Publication Open Access The utility of single-balloon enteroscopy for the diagnosis and management of small bowel disorders according to their clinical manifestations: a retrospective review(2013) Varayu Prachayakul; Morakod Deesomsak; Pitulak Aswakul; Somchai Leelakusolvong; Mahidol University. Siriraj Hospital. Department of Internal Medicineenteroscopy. However, the relative clinical advantages of the 2 methods remain controversial. This study therefore aimed to identify the indications for and therapeutic impact of performing single-balloon enteroscopy. Methods: We retrospectively reviewed.... Therapeutic procedures were performed in 11% of patients with GI bleeding and achieved a therapeutic yield of 14.6% with a minor complication rate of 11.7%. Conclusions: Single-balloon enteroscopy was effective for the diagnosis and treatment of small bowelPublication Open Access Roles of D-amino acids on the bioactivity of host defense peptides(2016-04) Hao Li; Nuttapat Anuwongcharoen; Aijaz Ahmad Malik; Chanin Nantasenamat; Mahidol University. Faculty of Medical Technology. Center of Data Mining and Biomedical InformaticsHost defense peptides (HDPs) are positively-charged and amphipathic components of the innate immune system that have demonstrated great potential to become the next generation of broad spectrum therapeutic agents effective against a vast array... of pathogens and tumor. As such, many approaches have been taken to improve the therapeutic efficacy of HDPs. Amongst these methods, the incorporation of D-amino acids (D-AA) is an approach that has demonstrated consistent success in improving HDPs. AlthoughPublication Open Access Impact of Dual Energy Window Scatter Correction on Image Quality in Tomographic Iodine 131(2018) Wirinya Saengthamchai; Supakiet Piasanthia; Kanokon Poonak; Putthiporn Charoenphun; Krisanat Chuamsaamarkkee; วิรินญา แสงธรรมชัย; ศุภเกียรติ เปียสันเทียะ; กนกอร ภู่นาค; พุทธิพรณ์ เจริญพันธุ์; กฤศณัฏฐ์ เชื่อมสามัคคี; Mahidol University. Faculty of Medicine Ramathibodi Hospital. Department of Diagnostic and Therapeutic Radiology; Navamindradhiraj University. Faculty of Medicine Vajira Hospital. Department of RadiologyBackground: The major limitation factors in single photon emission computed tomography (SPECT) detectability is the presence of scattered photons within the main photopeak. Objective: To evaluate the impact of dual-energy window (DEW) scatter... resulted in an increased of image noises for all sphere sizes and acquisition times when compared with NSC. To reveal the impact of scatter on contrast and noise, the CNR was investigated, our results found that the CNR for SC was higher than NSC whenPublication Open Access The Results of High-dose Rate Intracavitary Brachytherapy for Uterine Cervical Carcinoma in Ramathibodi Hospital(2009) Chuleeporn Jiarpinitnun; Chomporn Sitathanee; Mantana Dhanachai; ชุลีพร เจียรพินิจนันท์; ชมพร สีตะธนี; มัณฑนา ธนะไชย; Mahidol University. Faculty of Medicine Ramathibodi Hospital. Department of Diagnostic and Therapeutic RadiologyObjectives: To study results of high-dose-rate brachytherapy (HDR-BCT) for the treatment of cervical cancer patients in Ramathibodi Hospital in terms of tumor control, survival and treatment complications and to identify factors that may impactPublication Open Access Welfare effect of market exclusivity extension for patented medicines in Thailand: analysis of the effect of TRIPS-Plus provisions(2015-07) Theerathorn Yoongthong; Mahidol University. Institute for Population and Social ResearchUnder the free trade agreement negotiations with the United States and the European Union, Thailand, along with several developing countries, is required to enforce TRIPS-Plus provisions. Most developing countries claim that stringent intellectual property protection for pharmaceuticals would result in considerably higher prices for medicines, with adverse consequences for the health and well-being of their citizens. This paper empirically assesses the basis of these claims. Using a detailed product-level data set from Thailand, we estimate demand-side parameters together with key price and expenditure elasticities for a set of three main categories of antihypertensive drugs. We then use these estimates to carry out counterfactual simulations of what consumer welfare would have been, had Thailand enforced TRIPS-Plus. According to our estimation, the enforcement of TRIPS-Plus would result in a substantial accumulated consumer welfare loss to the Thai economy, ranging between 30 billion baht and 136 billion baht, within a 10-year period from 2012 to 2021. The magnitude of consumer welfare loss suggests that without clear and inclusive evidence regarding the merits of TRIPS-Plus in every aspect, Thailand should not accept any further intellectual property protection beyond the TRIPS mandates.Item Open Access Does social leisure contribute to physical health in MS related fatigue?(2008) Khemthong S.; Packer T. L.; Passmore A.; Dhaliwal S.; Supalak Khemthong; Packer Tanya L.; Passmore, Anne; Dhaliwal, Satvinder; ศุภลักษณ์ เข็มทอง; ทันยา แอล พาคเกอร์; แอน แพสมอ; ซัสวินดาร์ ดาวน์ลิวาว; Mahidol University. Faculty of Physical TherapyFatigue has a negative impact on both the performance of daily activities and health-related quality of life (HRQoL) especially in women with multiple sclerosis related fatigue (MSF). Previous research has suggested that leisure participation may..., George, Campbell, & Blazer, 1989), the Fatigue Impact Scale (FIS) (Fisk, et al., 1994), the Medical Outcome Study Short Form (SF-36), the Leisure Satisfaction Survey (LSS) (Beard & Ragheb, 1980), and the Classification of Leisure Participation ScaleItem Open Access Annual Report 2013 กองบริหารงานวิจัย มหาวิทยาลัยมหิดล(2014) มหาวิทยาลัยมหิดล. สำนักงานอธิการบดี. กองบริหารงานวิจัยPublication Open Access Drug pricing measures for the reimbursement(2012) Cha-oncin Sooksriwong; Wansuda Ngam-Aroon; Sunchai Janto; Mahidol University. Faculty of Pharmacyto the group HMG-CoA reductase inhibitor (statins) were purposive sampling to be the sample for the budget impact analysis. They were divided into 3 groups and the sample of each group was shown in the bracket: 1) Innovative drug with therapeutic improvement... the application of different drug pricing measures at the reimbursement level. Methods: This was a quantitative research. The budget impact analysis modeling to estimate the budget saved from the pricing policy implementation was employed. Drugs belongedPublication Open Access Using Video Modeling in Enhance Social Skills to Children With Autism: A Literature Review(2024) Pareyaasiri Witoonchart; Yun-Ju Huangtechnology in therapeutic intervention strategies, utilizes videos to exhibit desired behaviors and competencies. A total of 28 research articles, carefully selected from 3 reputable publication resources (APA PsycNet, Springer, and Eric), were analyzed..., and transferable skills. Furthermore, the paper presents empirical research findings that support the positive impact of video modeling on enhancing social skills in children with autism.Publication Open Access Determination of 2010 Reimbursed Drug Price and Its Budget Impact in Public Hospitals in Thailand(2012) Petcharat Pongcharoensuk; Angkana Saengnapakas; Oraluck Pattanaprateep; เพชรรัตน์ พงษ์เจริญสุข; Mahidol University. Faculty of Pharmacy; Mahidol University. Faculty of Medicine Ramathibodi Hospitalto determine the RP of five high expenditure drug groups and estimate the budget impact of RP implementation. Prescription records of 29 public hospitals in 2010 were collected. Drug utilization and several RP’s of each drug product were determined.... Then, overall budget impact was determined for RP under three different scenarios. Results showed that there were 1.7 million prescriptions, accounted for 2.5 billion baht. By drug group, total number of prescriptions were 39.96%, 26.25%, 16.57%, 13.68% and 3