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Item Metadata only Nanoencapsulation of Acetamiprid by Sodium Alginate and Polyethylene Glycol Enhanced Its Insecticidal Efficiency(2022-09-01) Ebadollahi A.; Valizadeh B.; Panahandeh S.; Mirhosseini H.; Zolfaghari M.; Changbunjong T.; Mahidol Universityfindings, the nanoencapsulation of acetamiprid by Al and PEG can increase its insecticidal performance in terms of lethal and sublethal toxicity....Nanoformulation has been considered one of the newly applied methods in integrated pest management strategies. In this research, a conventional neonicotinoid insecticide acetamiprid was nanoencapsulated via AL (Sodium Alginate) and PEG (PolyethyleneItem Metadata only Exposure of Young Children to Permethrin and Cypermethrin Insecticides in the Residential Environment(2024-07-01) Sirikanyaporn S.; Nankongnab N.; Kongtip P.; Siri S.; Suk W.A.; Woskie S.R.; Sirikanyaporn S.; Mahidol University, household characteristics, insecticide usage and exposure-related behavior in children was used to interview parents or family caregivers. Permethrin and cypermethrin concentrations on floor surfaces and children’s hands, as well as their urinary metabolites... metabolites were 0.84, 0.31 and 1.23 nmol/g creatinine, respectively. This study found that household insecticide product usage and having a tile floor were associated with increased permethrin concentrations on the children’s hands and floor surfaces. HoweverPublication Metadata only Longitudinal study of thyroid hormones between conventional and organic farmers in Thailand(2020-12-01) Noppanun Nankongnab; Pornpimol Kongtip; Nichcha Kallayanatham; Ritthirong Pundee; Jutharak Yimsabai; Susan Woskie; University of Massachusetts Lowell; Mahidol University; Buddhachinaraj Phitsanulok Hospital; EHTwhile controlling gender, baseline age, and body mass index (BMI) was used to compare between conventional and organic farmers or the impact of cumulative days of spraying insecticides, herbicides or fungicides. The estimated marginal means... of the thyroid hormone levels (TSH, FT3, T3, and T4) estimated from the linear mixed models were significantly higher among the conventional farmers than organic farmers. As cumulative spray days of insecticide, herbicide or fungicide increased, TSH and FT3Item Metadata only Urinary Cypermethrin Metabolites among Conventional and Organic Farmers in Thailand(2023-06-01) Tremongkoltip A.; Pengpumkiat S.; Kongtip P.; Nankongnab N.; Siri S.; Woskie S.; Mahidol UniversityCypermethrin, a pyrethroid insecticide, is frequently spread on agricultural farmlands and is also used in households in Thailand. Conventional pesticide-using farmers (n = 209) were recruited from the Phitsanulok and Nakornsawan provinces... any cypermethrin or with organic farmers, a significant difference was noted for all metabolites except for trans-DCCA. These findings show that the most significant exposures to cypermethrin are among conventional farmers who use the insecticidePublication Metadata only Acute imidacloprid poisoning in thailand(2020-01-01) Charuwan Sriapha; Satariya Trakulsrichai; Achara Tongpoo; Aimon Pradoo; Panee Rittilert; Winai Wananukul; Faculty of Medicine, Ramathibodi Hospital, Mahidol University© 2020 Sriapha et al. Introduction: Imidacloprid is the most commonly used neonicotinoid insecticide world-wide. Despite its reputation for safety, there is increasing evidence regarding its toxicity. This study characterized the clinical....8%) with no corrosive injuries and neurological effects (14.2%). The majority of medical outcomes was no (18.4%) to mild (76.1%) toxicity. One patient had symptoms mimicking cholinergic syndrome, three developed liver injury, and five died. Among the five deaths, twoItem Metadata only Biophysical Analysis of Vip3Aa Toxin Mutants Before and After Activation(2024-11-01) Khunrach P.; Surya W.; Promdonkoy B.; Torres J.; Boonserm P.; Khunrach P.; Mahidol Universityproblem. B. thuringiensis also produces vegetative insecticidal protein (Vip3A), which can kill insect targets in the same group as Cry toxins but using different host receptors, making the combined application of Cry and Vip3A an exciting possibility. Vip...3A toxicity requires the formation of a homotetramer. Hence, screening of Vip3A mutants for increased stability requires orthogonal biophysical assays that can test both tetrameric integrity and monomeric robustness. For this purpose, we have usedPublication Metadata only Urinary organophosphate metabolites and metabolic biomarkers of conventional and organic farmers in Thailand(2021-12-01) Pornpimol Kongtip; Noppanun Nankongnab; Nichcha Kallayanatham; Jutamanee Chungcharoen; Chanapa Bumrungchai; Sumate Pengpumkiat; Susan Woskie; University of Massachusetts Lowell; Mahidol University; EHT), and low-density lipoproteins (LDL) were measured. The average age, gender, education, and self-reported agricultural work time, work in second jobs, smoking status, alcohol consumption, insecticide use at home, home location near farmlands and yearsItem Metadata only Emamectin Poisoning in Thailand: Clinical Characteristics and Outcomes(2024-09-01) Trakulsrichai S.; Sittiyuno P.; Tansuwannarat P.; Tongpoo A.; Trakulsrichai S.; Mahidol UniversityEmamectin benzoate (Emamectin) is a broad-spectrum insecticide. Current data regarding emamectin poisoning in humans are very limited. We performed a 10-year retrospective cross-sectional study (2011–2020) using data from the Ramathibodi PoisonPublication Metadata only Acute changes in thyroid hormone levels among Thai pesticide sprayers(2021-01-01) Pornpimol Kongtip; Noppanun Nankongnab; Ritthirong Pundee; Nichcha Kallayanatham; Sumate Pengpumkiat; Jutamanee Chungcharoen; Chavisa Phommalachai; Pajaree Konthonbut; Nattagorn Choochouy; Preecha Sowanthip; Phanthawee Khangkhun; Jutharak Yimsabai; Susan Woskie; University of Massachusetts Lowell; Thailand Ministry of Public Health; Mahidol University; Thammasat University; Buddhachinaraj Phitsanulok Hospital; EHTThe objective of this study was to investigate the relationship of acute pesticide exposures and acute changes in thyroid hormones among Thai farmers. We recruited 78 farmers, who were scheduled to spray insecticides (chlorpyrifosItem Metadata only Metabolomic insights into rotenone-induced dysregulation of purine metabolism and impaired insulin secretion in murine pancreatic beta cells(2025-01-01) Ngamratanapaiboon S.; Yambangyang P.; Duchda P.; Lohwacharin J.; Devakul Na Ayutthaya W.; Ngamratanapaiboon S.; Mahidol UniversityRotenone, an insecticide, and herbicide has been associated with various environmental and health concerns. This study investigates the molecular alterations in rotenone-treated murine pancreatic beta cells, using untargeted metabolomics based... on liquid chromatography-mass spectrometry. We established a model mimicking rotenone toxicity in MIN6 cells and observed decreased insulin secretion despite no significant loss of cellular viability. Our untargeted metabolomics analysis revealed a decrease