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Publication Open Access Treatment of laryngeal paralysis in captive wild felids; Arytenoid lateralization technique(2012) Phingphol Charoonrut; Sukanya Manee-in; Ruangrat Buddhirongawat; Siriporn Tangsudjai; Nareerat Sungchachai; Tipapan Parnluck; Luxsana Pasittichai; Mahidol University. Faculty of Veterinary Sciencetigers and 2 lion with bilateral laryngeal paralysis were included. The surgical procedure was performed by left unilateral arytenoid lateralization in all animals. The better clinical signs after operation were shown in 7 animals except 1 lion... that was not improved and died 14 days after operation because of pre-operative systemic infection. One tiger died with the recurrent problem at 10 days after operation because of the laceration at the muscular process of arytenoid cartilage at prosthesis anchoredPublication Open Access Three phase bone scintigraphy in evaluating revascularization and bone formation of natural biomaterial bone graft by using Tc99m MDP in rabbits(2015) Somkiat Huaijantug; Paranee Yatmark; Somsak Wattananit; Phingphol Charoonrut; Thonnapong Thongpraparn; Rujaporn Chanachai; Mahidol University. Faculty of Veterinary Science; Mahidol University. Faculty of Medicine Siriraj Hospitalautogenous bone graft. A post-operative scanning of bone using TPBS was done at 7 days and weekly, at week 1, 2, 4, 6, 8, 12 to evaluate revascularization and bone formation of natural biomaterial bone graft comparing with autogenous bone graftPublication Open Access Quantitative evaluation of cellular intensity in cytologic staining over difference time period of post air-dried smear in canine mammary gland tumor(2018) Jeerasak sri-in; Pattita Ruayaree; Panpaga Sangsuriya; Panop wilainam; Parin Suwannaprapha; จีรศักดิ์ ศรีอินทร์; ปทิตตา รวยอารี; พรรณพงา เเสงสุริยะ; ภานพ วิไลนาม; ปริญ สุวรรณประภา; จุฬาลงกรณ์มหาวิทยาลัย. คณะเภสัชศาสตร์; มหาวิทยาลัยมหิดล. คณะสัตวแพทยศาสตร์. ภาควิชาปรีคลินิกและสัตวศาสตร์ประยุกต์interval time of post air-dried smear by usage of light microscope and computer software. The results showed that the intensity of cells, nucleus, cytoplasm, and the percentage of neoplastic cells with distinct cell boundaries, which were parameters... indicating staining quality, were statistical significant at all period of post air-dried smear when compared to specimens immediately stained (p<0.05). In conclusion, the results were demonstrated that any delay in staining post air-dried smears affectedPublication Open Access Preliminary report: Homology Modeling of human, dog and catβ-adrenergic receptors(2012) Waraphan Toniti; Pranom Puchadapirom; Aekkapot Chamkasem; Tawewan Tansatit; Mahidol University. Faculty of Veterinary Science. Department of Pre-clinic and Applied Animal Sciences; Mahidol University. Faculty of Science. Department of PathobiologyBeta 2-adrenergic Receptors are widely distributed in heart, airway smooth muscle, liver, skeletal muscle and adipose tissue. The specific ligand, beta 2-agonist, binds at the specific binding site on ADRB2 then the signal transduction pathways begins. The three-dimensional configuration of ADRB2 is uniquely and determines by its amino acid sequence. In this study, human ADRB2, dog ADRB2, and cat ADRB2 sequences were studied by sequence of P07550, P54833 and Q9TST5, respectively. The similarity of human ADRB2 and dog ADRB2 was 90% whereas the similarity between human ADRB2 and cat ADRB2 was 89%. In addition, the similarity between dog ADRB2 and cat ADRB2 was 95%. The in silico ADRB2 models were generated and compared among species of interest. The results show that the shapes and the pocket sites of ADRB2 differ between species. The differences of ADRB2 three-dimensional configuration may give explanations about the variety of interaction between ADRB2 and its agonist among human, dog and cat. Further study of protein-protein interaction, structure-based drug design, and novel function of ADRB2 in companion animals may have basis from human ADRB2.