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Publication Metadata only Antioxidant, a-Glucosidases and a-Amylase Inhibitory Activities of Persicaria odorata(2021-07-01) Kanya Thongra-ar; Piyanuch Rojsanga; Savita Chewchinda; Supachoke Mangmool; Pongtip Sithisarn; Mahidol UniversityThe objects of this study were to determine the effects to reactive oxygen species and antioxidant enzymes levels in HEK-293 cells and inhibition of α-glucosidases and α-amylase enzymes of extracts from Persicaria odorata or phak phaeo. The ethanol....99 ± 1.45 µg/mL, respectively and also strong inhibition to a-amylase with IC50 values of 90.66 ± 8.75 and 19.96 ± 5.37 µg/mL, respectively). Lineweaver-Burk plot demonstrated that phak phaeo extracts inhibited a-glucosidase and a-amylase in nonItem Metadata only Stability of salivary cortisol, alpha-amylase, and chromogranin A after long-term storage(2026-12-01) Pachimsawat P.; Jantaratnotai N.; Pachimsawat P.; Mahidol University, there is no consensus over how long the saliva can be stored where the values of these markers remain stable. This study aims to investigate whether storage duration affects the measured concentrations of salivary cortisol (sCort), alpha-amylase (sAA), and chromograninItem Metadata only The antioxidant activities and inhibitory effects on α-glucosidase and α-Amylase of ethanolic and aqueous extracts from various parts of Thai Caesalpinia sappan L.(2023-01-01) Boonmee A.; Moonrungsee N.; Kasemsuk T.; Puckdee W.; Komonpanich P.; Kunsook C.; Khamchatra N.M.; Nakeim S.; Khamchutra A.; Suninthaboonrana R.; Chairatana P.; Toviwek B.; Pongprayoon P.; Suwancharoen S.; Mahidol Universitythe highest inhibitory effect against α-Amylase, while CAE of barks shows better α-glucosidase inhibitory activity than the existing glucosidase inhibitor (acarbose). Molecular docking of brazilin (key bioactive compound) to both α-Amylase and glucosidase canPublication Metadata only Differential responses of salivary cortisol, amylase, and chromogranin A to academic stress(2021-08-01) Manita Tammayan; Nattinee Jantaratnotai; Praewpat Pachimsawat; Mahidol University, Faculty of Dentistry; Mahidol Universityactivity (cortisol; sCort) and the sympathetic activity (alpha-amylase; sAA and chromogranin A; sCgA), using academic oral presentation as a model of stress. Twenty postgraduate dental students attended the seminar class as presenter and audienceItem Metadata only UHPLC Analysis of Phenolic Compounds from Phanera strychnifolia Leaf Extracts, and Their Alpha-glucosidase and Alpha-Amylase Inhibitory Activities Supported by Molecular Docking(2026-08-01) Kongkiatpaiboon S.; Tayana N.; Seaho B.; Schinnerl J.; Duangdee N.; Inthakusol W.; Mudjupa C.; Chewchinda S.; Kongkiatpaiboon S.; Mahidol UniversityPhanera strychnifolia is a traditional medicinal plant showing remarkable antihyperglycemic activity. To develop as a phytopharmaceutical product for Diabetes, an in-depth investigation of the α-glucosidase and α-amylase inhibitory activitiesItem Metadata only Kluai Hin (Musa sapientum Linn.) peel as a source of functional polyphenols identified by HPLC-ESI-QTOF-MS and its potential antidiabetic function(2022-12-01) Tongkaew P.; Tohraman A.; Bungaramphai R.; Mitrpant C.; Aydin E.; Mahidol UniversityKluai Hin banana peel and pulp (methanol:water; M:W, 80:20 for flavonoids and acetone:water:acetic acid; A:W:A, 50:49:1 for phenolic acids) by RP-HPLC-DAD and HPLC-ESI-QTOF-MS. Additionally, inhibition of α-amylase and α-glucosidase activities...) than the freeze-dried peel (565.03 mg GAE/100 g). A:W:A extraction of the fresh and freeze-dried peel of exhibited IC50 values for α-amylase activity 2.66 ± 0.07 mg/ml and 2.97 ± 0.00 mg/ml, respectively, but its inhibitory activity was lower thanItem Metadata only Exploring anti-diabetic potential of compounds from roots of Dendrobium polyanthum Wall. ex Lindl. through inhibition of carbohydrate-digesting enzymes and glycation inhibitory activity(2024-07-30) Cheun-Arom T.; Kitisripanya T.; Nuntawong P.; Sritularak B.; Chuanasa T.; Cheun-Arom T.; Mahidol Universityfor inhibitory activities against alpha-glucosidase, alpha-amylase, and advanced glycation end products (AGEs) production. Additionally, molecular docking was conducted to analyze the interactions of the test compounds with alpha-glucosidase. Moscatin, the only... isolated phenanthrene, displayed the strongest anti–alpha-glucosidase activity with an IC50 of 32.45 ± 1.04 μM, approximately 10-fold smaller than that of acarbose. Furthermore, moscatilin most strongly inhibited alpha-amylase and AGEs production with IC50Publication Metadata only The calming effect of roasted coffee aroma in patients undergoing dental procedures(2021-12-01) Praewpat Pachimsawat; Kanlayanee Tangprasert; Nattinee Jantaratnotai; Mahidol Universityprocedures (probing and scaling). Salivary α-amylase (sAA) and cortisol (sCort) levels were measured as proxies of sympathetic nervous system and hypothalamic–pituitary–adrenal axis responses to stress respectively. Blood pressures and pulse rates wereItem Metadata only Low serum lipase levels in mothers of children with stunted growth indicate the possibility of low calcium absorption during pregnancy: A cross-sectional study in North Sumatra, Indonesia(2024-06-01) Sari D.K.; Amelia R.; Masyithah D.; Tantrakarnapa K.; Sari D.K.; Mahidol University, and laboratory examinations, including measurements of calcium, iron, zinc, vitamin D, pancreatic amylase, and serum lipase levels. This study included 50 healthy mothers aged 18–50 years old with children aged 2 to 60 months. There was a significant differenceItem Metadata only Baseline states of mind differentially affected diurnal salivary stress biomarkers: A preliminary study(2022-09-01) Jantaratnotai N.; Anh Do T.K.; Tammayan M.; Pachimsawat P.; Mahidol UniversityThe study aimed to determine how different baseline states of mind in each day (relaxed, ordinary, or stressful) affected the diurnal patterns of three commonly investigated salivary stress biomarkers: cortisol (sCort), alpha-amylase (s