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Item Metadata only Plasmodium falciparum : studies on antimalarial chalcone-chloroquine combination and development of fluorescence-bases antimalarial assay(Mahidol University. Mahidol University Library and Knowledge Center, 2023) Nongluk Sriwilaijaroen; Prapon WilairatItem Metadata only Isolation and identification of antimalarial substances from streptomyces culture broth(Mahidol University. Mahidol University Library and Knowledge Center, 2024) Pattra Suntornthiticharoen; Peerapan Tan-ariya; Vithaya Meevootisom; Yodhathai ThebtaranonthStreptomyces sp. var. 245.1, a new isolate of Streptomyces from soil collected from Petchaboon province (northern Thailand), was used as a producer of an antimalarial substance. The antimalarial activity was determined by using the in vitro... of the organism was done in both small and large scales. The antimalarial substance(s) from small scale cultivation was extracted with dichloromethane and ethyl acetate and then partially purified-by preparative thin-layer chromatography (PLC). The fractions namedItem Metadata only Antimalarial efficacy and toxicological assessment of medicinal plant ingredients of Prabchompoothaweep remedy as a candidate for antimalarial drug development(2023-12-01) Chaniad P.; Techarang T.; Phuwajaroanpong A.; Plirat W.; Viriyavejakul P.; Septama A.W.; Punsawad C.; Mahidol UniversityBackground: Drug resistance exists in almost all antimalarial drugs currently in use, leading to an urgent need to identify new antimalarial drugs. Medicinal plant use is an alternative approach to antimalarial chemotherapy. This study aimed... to explore potent medicinal plants from Prabchompoothaweep remedy for antimalarial drug development. Methods: Forty-eight crude extracts from Prabchompoothaweep remedy and its 23 plants ingredients were investigated in vitro for antimalarial properties usingItem Metadata only Clinical pharmacology of antimalarials(1993) Juntra Karbwang; Walther H. Wernsdorfer; Mahidol University. Faculty of Tropical MedicineItem Metadata only Target guided synthesis of 5-Benzyl-2,4-diaminopyrimidine antimalarials(Mahidol University. Mahidol University Library and Knowledge Center, 2023) Chawanee Sirichaiwat; Yodhathai Thebtaranonth.Item Open Access The antimalarial drug dihydroartemisinin: Formulation design and challenges in drug development(2019) Satit Puttipipatkhachorn; สาธิต พุทธิพิพัฒน์ขจร; Mahidol University. Faculty of Pharmacy. Department of Manufacturing PharmacyMalaria is an important cause of death and illness in children and adults, especially in tropical countries. Artemisinin-based combination therapy is currently the gold standard of antimalarial therapy, recommended in the WHO Guidelines.... Artemisinin, also called qinghaosu, is naturally occurring sesquiterpine lactone endoperoxide isolated from the traditional Chinese medicinal plant qinghao. Artemisinin shows a potent antimalarial activity against resistant strains of Plasmodium falciparumItem Metadata only Antimalarial activity of artemisinin : an iron-dependent mechanism of action(Mahidol University. Mahidol University Library and Knowledge Center, 2023) Nathawut Sibmooh; Udom Chantharaksri; Jutamaad Satayavivad; Supeenun UnchernItem Metadata only Mechanism of antimalarial action of tetracycline(Mahidol University. Mahidol University Library and Knowledge Center, 2024) Phisit Prapunwattana; Yongyuth Yuthavong; Pintip Ruenwongsa; Thanit KusamranPublication Metadata only Benefits of a pharmacology antimalarial reference standard and proficiency testing program provided by the Worldwide Antimalarial Resistance Network (WWARN)(2014-01-01) Chris Lourens; Niklas Lindegardh; Karen I. Barnes; Philippe J. Guerin; Carol H. Sibley; Nicholas J. White; Joel Tarning; Mahidol University; Nuffield Department of Clinical Medicine; University of Cape Town; University of Washington, SeattleComprehensive assessment of antimalarial drug resistance should include measurements of antimalarial blood or plasma concentrations in clinical trials and in individual assessments of treatment failure so that true resistance can be differentiated... laboratories, it is essential that drug concentration measurement is accurate. Proficiency testing (PT) of laboratory procedures is necessary for verification of assay results. Within the Worldwide Antimalarial Resistance Network (WWARN), the goalItem Metadata only Assessment of utilization of chloroquine and other antimalarial drugs in mataria endemic communities in Thailand(1991) Wijitr Fungladda; วิจิตร ฟุ้งลัดดา; Mahidol University. Faculty of Tropical Medicine. Department of Social and Environmental Medicine