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Item Metadata only Quantitative proteomic analysis of plasmodium vivax UIS3-induced proteome by label-free LC-MS(2014) Peerut Chienwichai; พีรุทย์ เชียรวิชัย; Wang Nguitragool; Jetsumon Prachumsri; เจตสุมน ประจำศรี; Supachai Topanurak; ศุภชัย โตภาณุรักษ์; Mahidol University. Faculty of Tropical Medicine. Department of Social and Environmental Medicine; Mahidol University. Faculty of Tropical Medicine. Department of Molecular Tropical Medicine and Genetics; Mahidol University. Faculty of Tropical Medicine. Mahidol Vivax Research UnitApicomplexans lack the ability to synthesize fatty acids de novo because it is different from human fatty acid synthesis. Plasmodium has an essential unique protein on its parasitovacuole membrane (PVM) called UIS3 (upregulated infective sporozoitePublication Metadata only Characterization of the ATP4 ion pump in Toxoplasma gondii(2019-01-01) Adele M. Lehane; Adelaide S.M. Dennis; Katherine O. Bray; Dongdi Li; Esther Rajendran; James M. McCoy; Hillary M. McArthur; Markus Winterberg; Farid Rahimi; Christopher J. Tonkin; Kiaran Kirk; Giel G. Van Dooren; Walter and Eliza Hall Institute of Medical Research; University of Melbourne; Mahidol University; Australian National University; Nuffield Department of Clinical Medicinesuggests that it is a Na efflux pump, extruding Na in exchange for H. Here we demonstrate that ATP4 proteins belong to a clade of P-type ATPases that are restricted to apicomplexans and their closest relatives. We employed a variety of genetic... and physiological approaches to investigate the ATP4 protein of the apicomplexan Toxoplasma gondii, TgATP4. We show that TgATP4 is a plasma membrane protein. Knockdown of TgATP4 had no effect on resting pH or Ca2 but rendered parasites unable to regulatePublication Metadata only Investigation of Nematopsis spp. oocysts in 7 species of bivalves from Chonburi Province, Gulf of Thailand(2004-01-28) C. Tuntiwaranuruk; K. Chalermwat; E. S. Upatham; M. Kruatrachue; C. Azevedo; Burapha University; Mahidol University; Department of Cell Biologythe prevalence of the apicomplexan parasite Nematopsis Schneider, 1892. Nematopsis spp. sporozoites were found in the cultivated bivalves Aicuatula arcuatula, Anadara granosa and Perna viridis as well as the locally harvested Paphia undulata. They were not found.... granosa, 17.61 ± 0.69/12.72 ± 0.36 μm (n = 50) for P. viridis, and 11.21 ± 0.62/8.55 ± 0.52 μm (n = 50) for P. undulata. Identification of oocysts of these apicomplexan gregarines to species was not attempted. The prevalence of infection in relationItem Metadata only Immunoproteomics to identify species-specific antigens in Neospora caninum recognised by infected bovine sera(2022-01-01) Udonsom R.; Reamtong O.; Adisakwattana P.; Popruk S.; Jirapattharasate C.; Nishikawa Y.; Inpankaew T.; Toompong J.; Kotepui M.; Mahittikorn A.; Mahidol Universityproduct, rhoptry protein (ROP1), possessing strong immunoreactivity against N. caninum but with no data on function available. Moreover, we identified cross-reactive antigens among these apicomplexan parasites, especially N. caninum, T. gondii and C... by these apicomplexan protozoan parasites.Publication Metadata only Comparative genome-wide analysis and evolutionary history of haemoglobin-processing and haem detoxification enzymes in malarial parasites(2016-01-29) Patrath Ponsuwanna; Theerarat Kochakarn; Duangkamon Bunditvorapoom; Krittikorn Kümpornsin; Thomas D. Otto; Chase Ridenour; Kesinee Chotivanich; Prapon Wilairat; Nicholas J. White; Olivo Miotto; Thanat Chookajorn; Mahidol University; Faculty of Medicine, Siriraj Hospital, Mahidol University; Wellcome Trust; Nuffield Department of Clinical Medicine; Wellcome Trust Sanger Institute; University of Oxfordprocessing machineries within Plasmodium species, and with the representatives of Apicomplexan species with various host tropisms, were created. Genetic variants were mapped onto existing three-dimensional structures. Genome-wide single nucleotide... in every Apicomplexan species. Haemoglobin-specific falcipains are separated from invasion-related falcipain, and their expansions within one specific locus arose independently in both P. falciparum and P. vivax lineages. Gene conversion between PItem Metadata only Sideways: road to gene-by-gene functional screening in malaria parasites(2023-05-01) Chookajorn T.; Billker O.; Mahidol UniversityGenome-wide screening in apicomplexan species has transformed our understanding of these parasitic protozoa. Kimmel et al. report a 'knock sideways' system and provide a powerful use case for its feasibility in a gene-by-gene screening in PlasmodiumPublication Metadata only Toxoplasma gondii: Simple duplex RT-PCR assay for detecting SAG1 and BAG1 genes during stage conversion in immunosuppressed mice(2010-02-01) Aongart Mahittikorn; Hannes Wickert; Yaowalark Sukthana; Mahidol University; Medical Laboratories Dr. Staber and Partner; Julius-Maximilians-Universitat WurzburgToxoplasmic encephalitis (TE) is caused by reactivation of dormant bradyzoites into rapidly dividing tachyzoites of the apicomplexan parasite Toxoplasma gondii in immune-compromised hosts. Diagnosis of this life-threatening disease is complicatedPublication Metadata only Toxoplasma gondii: simple duplex RT-PCR assay for detecting SAG1 and BAG1 genes during stage conversion in immunosuppressed mice(2010) Aongart Mahittikorn; Wickert, Hannes; Yaowalark Sukthana; Mahidol University. International College.Toxoplasmic encephalitis (TE) is caused by reactivation of dormant bradyzoites into rapidly dividing tachyzoites of the apicomplexan parasite Toxoplasma gondii in immune-compromised hosts. Diagnosis of this life-threatening disease is complicatedPublication Metadata only Toxoplasma gondii and neospora caninum prevalence and risk factors on goat farms in Kanchanaburi province, Thailand(2020-01-01) Ruenruetai Udonsom; Jarawee Supanta; Onrampha Tanglakmankhong; Kanamon Ngoenphisutsin; Yoshifumi Nishikawa; Ragab M. Fereig; Charoonluk Jirapattharasate; South Valley University; Mahidol University; Obihiro University of Agriculture and Veterinary Medicine© 2020, Chiang Mai University - Faculty of Veterinary Medicine. All rights reserved. Toxoplasma gondii and Neospora caninum are apicomplexan protozoan parasites that have been associated with reproductive problems in ruminants. Despite the highItem Metadata only First detection and molecular identification of Babesia gibsoni and Hepatozoon canis in an Asiatic wild dog (Cuon alpinus) from Thailand(2022-04-01) Bhusri B.; Lekcharoen P.; Changbunjong T.; Mahidol UniversityBabesia spp. and Hepatozoon spp. are apicomplexan parasites that infect a wide range of domestic and wild animals. The life cycle of these parasites requires a tick vector as a definitive host and various vertebrates as reservoir hosts