Search Results

Now showing 1 - 10 of 1110
  • Publication
    Use of nutritional biomarkers in program evaluation in the context of developing countries
    (2012-01-01) Emorn Wasantwisut; Lynnette Neufeld; Mahidol University; The Micronutrient Initiative
    The Lancet series onmaternal and child undernutrition emphasized the need for accurate and reliable biomarkers that reflect nutrient status andmeasure the impact of interventions. An initiative called Biomarkers of Nutrition for Development (BOND...) by the Eunice Kennedy Shriver National Institute of Child Health and Human Development aims to provide guidance for the selection and interpretation of biomarkers that meet a range of interests, including research, clinical policy, and program development
  • Item
    Identification of Biomarkers in Burkholderia Pseudomallei using Whole-Cell Maldi-TOF MS
    (Mahidol University. Mahidol University Library and Knowledge Center, 2023) Suthamat Niyompanich; Sumalee Tungpradabkul; Wilai Noonpakdee; Thaned Kangsamaksin; Jamorn Somana
    reliably identified as B. pseudomallei, based on five taxon- specific biomarkers and the identification scores obtained from BioTyper analysis. Cluster analysis of the environmental and clinical isolates revealed that six out of eleven isolates were... correctly clustered according to their isolation sources. Upon further analysis using ClinProTools software, ten source-specific biomarkers were obtained according to their respective sources. Among these, six biomarkers (m/z 4056, 4214, 5814, 7545, 7895
  • Item
    Renal biomarkers in cats: A review of the current status in chronic kidney disease
    (2022-03-01) Kongtasai T.; Paepe D.; Meyer E.; Mortier F.; Marynissen S.; Stammeleer L.; Defauw P.; Daminet S.; Mahidol University
    Serum creatinine concentration, the classical biomarker of chronic kidney disease (CKD) in cats, has important limitations that decrease its value as a biomarker of early CKD. Recently, serum symmetric dimethylarginine concentration was introduced... as a novel glomerular filtration rate biomarker for the early detection of CKD in cats. However, data on its specificity are still limited. The limitations of conventional biomarkers and the desire for early therapeutic intervention in cats with CKD
  • Publication
    Recent applications of paper-based point-of-care devices for biomarker detection
    (2019-01-01) Worapot Suntornsuk; Leena Suntornsuk; Mahidol University; King Mongkut s University of Technology Thonburi
    © 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Detection of biomarkers is essential for diagnosis and prognosis of diseases for healthcare teams to provide timely appropriate treatments. Reliable, inexpensive, and sensitive devices... are desirable to serve this purpose. Paper-based analytical devices (PADs) have gained enormous attention during the past decade as point-of-care devices for biomarker detection due to their simplicity, portability, and biocompatibility. Importantly, the devices
  • Publication
    Molecular biomarkers for quantitative and discrete COPD phenotypes
    (2009-03-01) Soumyaroop Bhattacharya; Sorachai Srisuma; Dawn L. Demeo; Steven D. Shapiro; Raphael Bueno; Edwin K. Silverman; John J. Reilly; Thomas J. Mariani; Harvard Medical School; Brigham and Women's Hospital; Mahidol University; University of Rochester; University of Pittsburgh
    Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disorder with complex pathological features and largely unknown etiology. The identification of biomarkers for this disease could aid the development of methods to facilitate... earlier diagnosis, the classification of disease subtypes, and provide a means to define therapeutic response. To identify gene expression biomarkers, we completed expression profiling of RNA derived from the lung tissue of 56 subjects with varying degrees
  • Item
    A Systematic Review and Meta-Analysis Assessing the Accuracy of Blood Biomarkers for the Diagnosis of Ischemic Stroke in Adult and Elderly Populations
    (2024-11-01) Ruksakulpiwat S.; Zhou W.; Phianhasin L.; Benjasirisan C.; Su T.; Aldossary H.M.; Kudlowitz A.; Challa A.K.; Li J.; Praditukrit K.; Ruksakulpiwat S.; Mahidol University
    This study aims to elucidate the methodology and compare the accuracy of different blood biomarkers for diagnosing ischemic stroke (IS). We reviewed 29 articles retrieved from PubMed, MEDLINE, Web of Science, and CINAHL Plus with Full Text. Among.... Blood biomarkers from noninpatient settings demonstrated better diagnostic performance than those in inpatient settings (AUC 0.91 vs 0.88). Smaller sample sizes (<100) showed better performance than larger ones (≥100; AUC 0.92 vs 0.86). Blood biomarkers
  • Publication
    Glycocalyx damage biomarkers in healthy controls, abdominal surgery, and sepsis: a scoping review
    (2020-01-01) Fumitaka Yanase; Thummaporn Naorungroj; Rinaldo Bellomo; University of Melbourne; Monash University; Faculty of Medicine, Siriraj Hospital, Mahidol University; Austin Hospital
    © 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group. Objective: Despite wide interest in glycocalyx biomarkers, their values in healthy individuals, patients after abdominal surgery, and septic patients have been poorly understood.... Methods: We searched MEDLINE, CENTRAL and EMBASE for papers measured glycocalyx biomarkers in healthy individuals, patients after abdominal surgery and septic patients. Results: We extracted 3948 titles and identified 58 eligible papers. Syndecan 1
  • Item
    Expert recommendations for biomarker evaluation of advanced non-small cell lung cancer in Thailand
    (2025-07-31) Shuangshoti S.; Prasongsook N.; Thamlikitkul L.; Reungwetwattana T.; Poungvarin N.; Jinawath A.; Teerapakpinyo C.; Vinyuvat S.; Sriuranpong V.; Shuangshoti S.; Mahidol University
    . Practical barriers, such as lack of awareness/understanding of biomarkers, suboptimal quality or sample management, inappropriate use of biomarker testing results, limited patient access to biomarker tests and targeted treatments, and reimbursement/payment... challenges, hinder the wider adoption of guideline-recommended biomarker testing. Limited reimbursement of targeted therapies is a key consideration for Thai oncologists when making a treatment choice for their patients with advanced NSCLC in Thailand. We aim
  • Publication
    Executive summary - Biomarkers of nutrition for development: Building a consensus
    (2011-08-01) Daniel J. Raiten; Sorrel Namasté; Bernard Brabin; Gerald Combs; Mary R. L'Abbe; Emorn Wasantwisut; Ian Darnton-Hill; National Institute of Child Health and Human Development; Liverpool School of Tropical Medicine; USDA ARS Grand Forks Human Nutrition Research Center; University of Toronto Faculty of Medicine; Mahidol University; The University of Sydney; Tufts University
    of food and nutrition in achieving those goals, relevant data are developed with the use of biomarkers that reflect nutrient exposure, status, and functional effect. A need exists to promote the discovery, development, and use of biomarkers across a range... of applications. In addition, a process is needed to harmonize the global health community's decision making about what biomarkers are best suited for a given use under specific conditions and settings. To address these needs, the Eunice Kennedy Shriver National
  • Item
    Role of biomarkers in predicting disease severity in acute dengue and SARs-CoV-2-Infected patients
    (2026-12-01) Yamasmith E.; Kinslow J.D.; Berg M.G.; Cloherty G.A.; Moy J.N.; Landay A.L.; Suputtamongkol Y.; Tantibhedhyangkul W.; Yamasmith E.; Mahidol University
    Purpose: The early stages of both dengue infection and COVID-19 can present similarly with acute febrile illness or influenza-like symptoms, and individuals with initially mild disease may progress to more severe symptoms. We performed biomarker... analysis to determine if host immune responses can predict the disease severity of both diseases. Methods: Differential immune response profiles in patient populations were compared during acute dengue or COVID-19 using a panel of 22 soluble biomarkers