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Now showing 1 - 10 of 27
  • Publication
    The integrity of the FOG-2 LXCXE pRb-binding motif is required for small intestine homeostasis
    (2019-07-01) Olivier Goupille; Zahra Kadri; Amandine Langelé; Sophie Luccantoni; Cécile Badoual; Philippe Leboulch; Stany Chrétien; Hopital Europeen Georges-Pompidou; Université Paris-Sud; Brigham and Women's Hospital; Faculty of Medicine, Ramathibodi Hospital, Mahidol University; Inserm
    © 2019 The Authors. Experimental Physiology © 2019 The Physiological Society New Findings: What is the central question of this study? Do Fog2Rb−/Rb− mice present a defect of small intestine homeostasis? What is the main finding and its importance...? The importance of interactions between FOG-2 and pRb in adipose tissue physiology has previously been demonstrated. Here it is shown that this interaction is also intrinsic to small intestine homeostasis and exerts extrinsic control over mouse metabolism. Thus
  • Publication
    The LXCXE Retinoblastoma Protein-Binding Motif of FOG-2 Regulates Adipogenesis
    (2017-12-19) Olivier Goupille; Tipparat Penglong; Zahra Kadri; Marine Granger-Locatelli; Raphaël Denis; Serge Luquet; Cécile Badoual; Suthat Fucharoen; Leila Maouche-Chrétien; Philippe Leboulch; Stany Chrétien; Universite Paris-Saclay; Mahidol University; Universite Paris 7- Denis Diderot; Hopital Europeen Georges-Pompidou; Inserm; Brigham and Women's Hospital and Harvard Medical School
    © 2017 The Author(s) GATA transcription factors and their FOG cofactors play a key role in tissue-specific development and differentiation, from worms to humans. Mammals have six GATA and two FOG factors. We recently demonstrated that interactions... between retinoblastoma protein (pRb) and GATA-1 are crucial for erythroid proliferation and differentiation. We show here that the LXCXE pRb-binding site of FOG-2 is involved in adipogenesis. Unlike GATA-1, which inhibits cell division, FOG-2 promotes
  • Publication
    Reality in package on-site grease trap performance: Success and failure in fog removal
    (2020-01-01) Sopa Chinwetkitvanich; Piti Ektaku; Mahidol University
    © Int. J. of GEOMATE. All rights reserved. Package on-site grease traps are widely used in household and restaurant in Thailand for oil and grease removal although frequent failures in FOG removal have been reported. Theoretically, too small... hours) and FOG concentrations in the feed (50 to 600 mg/l). Results showed that the operating HRTs of 15, 30 and 60 minutes could represent a kind of shock hydraulic loading condition, which insufficient FOG removal efficiencies were observed. Also
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    Validity and Reliability of the Thai Version of the Freezing of Gait Questionnaire in Individuals With Parkinson’s disease
    (2023-01-01) Taweekitikul A.; Tanvijit P.; Tantisuvanitchkul P.; Srivanitchapoom P.; Pitakpatapee Y.; Khobkhun F.; Akkathep P.; Mahidol University
    Objective To evaluate the validity and reliability of the Thai version of the Freezing of Gait Questionnaire (FOG-Q) in individuals with Parkinson’s disease (PD). Methods The FOG-Q was translated into Thai according to the standard process. Fifty...-six individuals with PD participated in the study. The content validity was assessed using the content validity index (CVI). The construct validity was evaluated by correlating Thai FOG-Q with Thai version of the Movement Disorder Society-sponsored
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    Smart ankle bracelet-laser device to improve gait and detect freezing of gait in Parkinsonism patients: a case series
    (2022-01-01) Ratanasutiranont C.; Srisilpa K.; Termsarasab P.; Ruthiraphong P.; Mahidol University
    Freezing of gait (FOG) is one of the most disabling symptoms of Parkinsonism. Moreover, it does not respond well to medication. Visual cues have been shown to alleviate FOG in Parkinsonism; however, their efficacy is inconsistent. Currently, most... measurements of FOG in real-life situations remain challenging. Therefore, we developed a smart-ankle laser as a closed-loop cueing system that can detect the patient’s walking pattern and automatically project a laser line that follows each walking step, thus
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    Systematic review of kinematic and kinetic parameters in Parkinson's disease, with and without freezing of gait
    (2026-07-01) Ball L.; Khobkhun F.; Richards J.; Davison G.; Bowd J.; Ball L.; Mahidol University
    Background: Parkinson's Disease (PD) is a chronic, progressive disorder, impairing gait, balance and overall functionality. Freezing of gait (FOG) is a debilitating and pervasive symptom of PD, presenting as an inability to make forward progression... despite the intention to walk. Commonly seen within FOG are rigid movements and postural instability, inducing a fear of falling which can inhibit quality of life. The aim of this review was to identify the key biomechanical parameters that differentiate
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    PublicationOpen Access
    การจัดการกากไขมันจากบ่อดักไขมัน โดยกระบวนการทำปุ๋ยหมักร่วมกับดินค่ำและขี้เลื่อย
    (2558) วิรจิรวัส รวิชญทรัพย์; ธวัช เพชรไทย; ธนาศรี สีหะบุตร; วรพจน์ กนกกันฑพงษ์; Tawach Prechthai; Tanasri Sihabut; ธวัช เพชรไทย; มหาวิทยาลัยมหิดล. คณะสาธารณสุขศาสตร์. ภาควิชาวิทยาศาสตร์อนามัยสิ่งแวดล้อม
    Fat, oil and grease (FOG) are residue organic waste usually removed from the grease trap using in household wastewater treatment. To prevent the environmental impact from FOG, therefore, it should be properly managed and disposed. Co-composting... process may be applicable for this waste in order to recycle FOG as soil conditioner. This study, therefore, is to determine the feasibility of co-composting process of FOG, night soil and sawdust. The composting material was prepared by mixing of 19
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    PublicationOpen Access
    การย่อยสลายกากไขมันของไส้เดือนดิน Pheretima peguana และ Eisenia foetida ในกระบวนการหมักมูลไส้เดือนของกากไขมันร่วมกับดินค่ำ
    (2558) ปวีณา เจริญอักษร; สุเทพ ศิลปานันทกุล; วิธิดา พัฒนาอิสรานุกุล; ธวัช เพชรไทย; Suthep Silapanuntakul; Withida Patthanaissaranukool; Tawach Prechthai; ธวัช เพชรไทย; มหาวิทยาลัยมหิดล. คณะสาธารณสุขศาสตร์. ภาควิชาวิทยาศาสตร์อนามัยสิ่งแวดล้อม; Mahidol university. Faculty of Public Health. Department of Environmental Health Sciences
    process for Fat, Oil and Grease (FOG) waste collected from grease traps of a municipal wastewater treatment system. Different ratios of FOG and night soil were prepared at 20%, 40% and 80% by weight for the vermicom- posting process. The composting... process without adding any earthworms was also done in all conditions. The removal effi ciencies and degradation coeffi cients of FOG were then determined after 84 days of vermicomposting time. The average FOG removal effi ciency at 20, 40 and 80
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    Ankle Bracelet Laser as a Novel Portable Device to Improve Walking in Patients With Parkinsonism: Randomized Crossover Controlled Trial
    (2025-01-01) Ruthiraphong P.; Srisilpa K.; Ratanasutiranont C.; Mres; Ruthiraphong P.; Mahidol University
    Background: Freezing of gait (FOG) is a common and debilitating symptom of parkinsonism. Although visual cues have proven efficacy in alleviating FOG, most current visual cues are fixed in place, restricting their use to controlled environments... with parkinsonism and FOG. Methods: A randomized controlled 2-period crossover trial was conducted from June 15, 2020, to October 1, 2020, at Ramathibodi Hospital. In total, 10 patients with parkinsonism and FOG were enrolled in 2 conditions: walking with laser-off
  • Publication
    Erythropoietin and IGF-1 signaling synchronize cell proliferation and maturation during erythropoiesis
    (2015-12-15) Zahra Kadri; Carine Lefevre; Olivier Goupille; Tipparat Penglong; Marine Granger-Locatelli; Suthat Fucharoen; Leila Maouche-Chretien; Philippe Leboulch; Stany Chretien; Institut des Maladies Emergentes et des Therapies Innovantes; Universite Paris-Saclay; Mahidol University; Inserm; Brigham and Women's Hospital
    © 2015 Kadri et al. Tight coordination of cell proliferation and differentiation is central to red blood cell formation. Erythropoietin controls the proliferation and survival of red blood cell precursors, while variations in GATA-1/FOG-1 complex... for FOG-1. In turn, FOG-1 displaces pRb/E2F-2 fromGATA-1, ultimately releasing free, proproliferative E2F-2. Mice bearing a Gata-1S310Amutation suffer fromfatal anemia when a compensatory pathway for E2F-2 production involving insulin-like growth factor-1