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Item Open Access Investigation on the efficiency of modified activated carbon for iodine-131 removal from a synthetic urine(Mahidol University., 2023) Sasiprapha Pochun; Putthiporn Charoenphun; Krisanat Chuamsaamarkkee; Pongtanawat Khemthong; Mahidol UniversityIodine-(131) is commonly used to treat thyroid cancer in nuclear medicine. Approximately 50-90% of the administered activity is excreted through urine in the first 24 hours, and it could cause unwanted exposure to the people nearby and environmental... the urine of patients treated with radioiodine. Implication of thesis: The efficiency of iodine-(131) removal from synthetic urine was investigated and compared between activated carbon (AC) and ammonia-doped activated carbon (NH3-AC). The batch experimentItem Metadata only Monitoring of radioiodine-131 contamination in the sewage system of Siriraj Hospital(Mahidol University. Mahidol University Library and Knowledge Center, 2009) Kusuma Tongsukh; Malulee TuntawiroonItem Metadata only Absolute quantitation of I-131 activity in thyroid gland by scinticamera(Mahidol University. Mahidol University Library and Knowledge Center, 2024) Veerathep Sataratanakul; Vipa Boonkitticharoen; Payap Chokesuwattanaskul; Ratana PirabulPublication Metadata only Comparative evaluation of two different dosage calculation protocols of iodine-131 in the treatment of hyperthyroidism(2010-08-01) Tanyaluck Thientunyakit; Suchitra Thongmak; Teerapon Premprapha; Mahidol University; Prince of Songkla UniversityObjective: To compare the effectiveness of radioiodine therapy with estimated dose and calculated dose in hyperthyroid patients. Material and Method: A prospective randomized study in 144 hyperthyroid patients referred for 131I treatment... was performed between June and December 2007. The patients were divided into two groups according to the I dose administered, estimated group using dose based on gland size and calculated group using dose based on both gland size and 24-hour 131I uptake. OutcomeItem Metadata only Correlation between serum thyroglobulin (Tg) value and the result of 131-iodine total body scan (131I TBS) after ablation in differentiated thyroid carcinoma (DTC)(Mahidol University. Mahidol University Library and Knowledge Center, 2006) Nantiya Rojanapong; Sunanta ChiewvitPublication Open Access Impact of Dual Energy Window Scatter Correction on Image Quality in Tomographic Iodine 131(2018) Wirinya Saengthamchai; Supakiet Piasanthia; Kanokon Poonak; Putthiporn Charoenphun; Krisanat Chuamsaamarkkee; วิรินญา แสงธรรมชัย; ศุภเกียรติ เปียสันเทียะ; กนกอร ภู่นาค; พุทธิพรณ์ เจริญพันธุ์; กฤศณัฏฐ์ เชื่อมสามัคคี; Mahidol University. Faculty of Medicine Ramathibodi Hospital. Department of Diagnostic and Therapeutic Radiology; Navamindradhiraj University. Faculty of Medicine Vajira Hospital. Department of Radiologyscatter correction could be degraded image quality in an iodine 131 (131I) SPECT when compared with uncorrected image....ไอโอดีน-131 ที่แก้รังสีกระเจิงด้วยวิธีการ Double energy window (DEW) และไม่แก้รังสีกระเจิง วิธีการศึกษา: การวิจัยทำในหุ่นจำลอง NEMA/IEC ที่ภายในประกอบด้วยลูกทรงกลมขนาดต่างๆ ที่สามารถบรรจุไอโอดีนรังสี-131 โดยกำหนดค่าความเข้มข้นของสารไอโอดีนรังสีในทรงกลมให้Item Metadata only Validation Calibration Factor of Single Photon Emission Computed Tomography for Iodine-131 using Non-Spherical Targeted Volume(2023-01-01) Masud M.A.; Ngali M.Z.; Othman S.A.; Taib I.; Osman K.; Salleh S.M.; Khudzari A.Z.M.; Ali N.S.; Chaichana A.; Masud M.A.; Mahidol UniversityAbsolute quantification of Iodine-131 (131I) on Single Photon Emission Computed Tomography (SPECT) imaging is extremely necessary for the lesion dose per administrative differentiated thyroid cancer procedure. However, non-quantitative SPECT imaging..., this study aims to determine the calibration factor (CF) for131I activity quantification using the National Electrical Manufacturer Association (NEMA) phantom uptake for the Philips BrightView XCT modality. The accuracy activity concentration for a nonItem Metadata only Production and evaluation of a reference standard charcoal cartridge for airborne radioiodine monitoring in nuclear medicine(Mahidol University. Mahidol University Library and Knowledge Center, 2024) Apichaya Techaphan; Krisanat Chuamsaamarkkee; Putthiporn Charoenphun; Thawatchai itthipoonthanankornRadioiodine-131 (131I) in the form of sodium iodide ( NaI) is the common therapeutic radiopharmaceutical used for thyroid diseases. However, it is volatile, also called airborne radioiodine which can cause the potentially internal exposure... to the radiation worker via the inhalation process. In nuclear medicine, the gaseous iodine is the major component of airborne radioiodine contamination. Therefore, the gaseous airborne radioiodine monitoring is required for the radiation safety of the radiationItem Metadata only Halogen-Bonding Interaction-Mediated Efficient Iodine Capture of Highly Nitrogen-Functionalized Hyper-Crosslinked Polymers(2024-01-01) Junthod K.; Todee B.; Khamphaijun K.; Chutimasakul T.; Sangtawesin T.; Ratvijitvech T.; Tantirungrotechai J.; Suriya U.; Bunchuay T.; Junthod K.; Mahidol UniversityRadioactive iodine species, 129I and 131I, are volatile radioactive nuclides generated from nuclear fission processes. The exposure of these isotopes has caused severe effects on the environment as a result of the long half-life of 129I and high... radiation energy of 131I. Therefore, ideal adsorbents capable of effectively adsorbing iodine from gas and solution phases have received particular attention. In this study, we applied the concept of supramolecular noncovalent interactions to designPublication Metadata only Iodine-131 metaiodobenzylguanidine (131I-mIBG) treatment in relapsed/refractory neuroblastoma(2020-04-01) Yoch Anongpornjossakul; Wattanun Sriwatcharin; Kanungnij Thamnirat; Wichana Chamroonrat; Arpakorn Kositwattanarerk; Chirawat Utamakul; Chanika Sritara; Payap Chokesuwattanasakul; Nintita Sripaiboonkij Thokanit; Samart Pakakasama; Usanarat Anurathapan; Pongpak Pongphitcha; Chanisa Chotipanich; Suradej Hongeng; Mahidol University; Cholabhorn HospitalBACKGROUND: I-meta-iodo-benzylguanidine (I-mIBG) therapy has been used in treatment of for advanced neuroblastoma for many years with promising results. There are several studies regarding predictors and outcomes of I-mIBG therapies in relapsed/refractory neuroblastoma patients. OBJECTIVE: To identify the predictors and outcomes of I-mIBG treatment in relapsed/refractory neuroblastoma. METHODS: This study was a retrospective review of 22 patients with high risk stage IV relapsed/refractory neuroblastoma who received at least one cycle of I-mIBG therapy. Patient' characteristics, hematologic toxicity, scintigraphic semi-quantitative scoring, and overall survival were recorded. Factors predicting survival were analyzed. RESULTS: Twenty-two patients (50% male) with mean age of 3.7 years (4.8 months to 8.3 years) received I-mIBG therapies at an average of 3.8 and mean dose of 136 mCi (5032 MBq) per treatment. Most common acute hematologic toxicity was thrombocytopenia. Overall 5-year survival rate was 37% (95% confidence interval: 16.3-58.0) and median survival time was 2.8 year (95% confidence interval: 1.38-6.34). Patients with rising Curie score of ≥25% upon the second therapy were major determinants of overall survival with poorer response to treatment. At least three treatments of I-mIBG were needed to identify some degrees of survival prolongation (crude hazard ratio: P-value = 0.003). Age, sex, metastatic status, and baseline Curie scoring system were good predictors associated with survival. Seven patients (32%) demonstrated objective responses. CONCLUSION: Despite multimodality therapy, high risk neuroblastoma had a propensity of treatment failure in terms of relapsed or refractory, with some objective responses after I-mIBG treatments. The declined or non-rising Curie score upon second post-treatment total body scan was an important predictor of survival and aided a decision whether or not to proceed with bone marrow transplantation.