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Item Open Access A preliminary study on the prevalence of PSTEIN-BARR virus in oral cavity in a group of Thais(Mahidol University, 2022) Pasinee Vorakulpipat; Siribang-On Piboonniyom Khovidhunkit; Nakarin Kitkumthorn; Puangwan LapthanasupkulTobacco smoking, betel quid chewing, and alcohol consumption are risk factors for oral cancer (OC) and oral potentially malignant disorders (OPMDs). Epstein-Barr virus (EBV) has also been suggested as one of the etiological factors of oral... malignancy. In this preliminary study, we focused on the prevalence of EBV in the oral cavity of people with risk factors for OC in a group of Thais.Using the scraping technique, oral epithelial cells were obtained from 65 participants aged over 40 yearsItem Metadata only Prevalence of Xerostomia and Hyposalivation Among Individuals Attending Oral Cancer Screening in Thailand: A Cross-Sectional Study(2024-01-01) Ekkert S.; Deeiam K.; Klongnoi B.; Sresumatchai V.; Pimolbutr K.; Khovidhunkit S.O.P.; Ekkert S.; Mahidol Universityof these conditions and their associated factors among individuals taking part in oral cancer screening and residing in the northeastern provinces of Thailand. Materials and Methods: This cross-sectional study recruited convenient individuals aged ≥40 years... with at least one oral cancer risk factor. In total, 561 participants were included. Demographic characteristics and relevant oral cancer risk factors were recorded. A questionnaire comprising five items was used to assess xerostomia. Participants werePublication Open Access Cigarette Plain Packaging Perceptions on Intent to Abstain from Smoking among Thai Female Youth(2019) Narumon Auemaneekul; Dusit Sujirarat; Pimpan Silpasuwan; Pratana Satitvipawee; Chukiat Viwatwongkasem; Malinee Sompopcharoen; Nithat Sirichotiratana; นฤมล เอื้อมณีกูล; ดุสิต สุจิรารัตน์; พิมพ์พรรณ ศิลปสุวรรณ; ปรารถนา สถิตย์วิภาวี; ชูเกียรติ วิวัฒน์วงศ์เกษม; มลินี สมภพเจริญ; นิทัศน์ ศิริโชติรัตน์; Mahidol University. Faculty of Public Health. Department of Public Health Nursing; Mahidol University. Faculty of Public Health. Department of Epidemiology; Mahidol University. Faculty of Public Health. Department of Biostatistics; Mahidol University. Faculty of Public Health. Department of Health Education and Behavioral Sciences; Mahidol University. Faculty of Public Health. Department of Public Health Administrationand implementing the plain packaging policy in ThailandPublication Open Access Activities of daily living associated with acquisition of melioidosis in northeast Thailand: a matched case-control study(2013-02) Direk Limmathurotsakul; ดิเรก ลิ้มมธุรสกุล; Manas Kanoksil; Vanaporn Wuthiekanun; วรรณพร วุฒิเอกอนันต์; Rungrueng Kitphati; Stavola, Bianca de; Day, Nicholas P.J.; Peacock, Sharon J.; Direk Limmathurotsakul; Mahidol University. Faculty of Tropical Medicine. Department of Tropical Hygiene; Mahidol University. Faculty of Tropical Medicine. Mahidol-Oxford Tropical Medicine Research Unit; Mahidol University. Faculty of Tropical Medicine. Department of Microbiology and Immunology1∶2 matched case-control study was conducted in Northeast Thailand. Cases were patients with culture-confirmed melioidosis, and controls were patients admitted with non-infectious conditions during the same period, matched for gender, age... analysis based on 286 cases and 512 controls showed that activities associated with a risk of melioidosis included working in a rice field (conditional odds ratio [cOR] = 2.1; 95% confidence interval [CI] 1.4-3.3), other activities associatedPublication Open Access Impact of economic fluctuation and 1997 Thailand economic crisis on cirrhosis cause of death(2009-07) Yothin Sawangdee; โยธิน แสวงดี; Piyawat Katewongsa; ปิยวัฒน์ เกตุวงศา; Wimontip Musikaphan; Boonlert Leoprapai; Mahidol University. Institute for Population and Social ResearchThis study examines the impact of economic fluctuation and 1997 Thailand economic crisis on cirrhosis cause of death among patients during 1980-2000. Materials and methods are time series data from Public Health Statistics and data on Gross DomesticPublication Open Access The Effects of a Constipation Prevention Program on Incidence and Severity of Constipation in Hospitalized Elderly undergoing Hip Surgery(2011) พวงผกา มั่นหมาย; Poungpaka Monmai; สุภาพ อารีเอื้อ; Suparb Aree-Ue; พรรณวดี พุธวัฒนะ; Panwadee Putwatana; วิโรจน์ กวินวงศ์โกวิท; Viroj Kawinwonggowit; มหาวิทยาลัยมหิดล. คณะแพทยศาสตร์โรงพยาบาลรามาธิบดี. ภาควิชาออร์โธปิดิกส์; มหาวิทยาลัยมหิดล. คณะแพทยศาสตร์โรงพยาบาลรามาธิบดี. โรงเรียนพยาบาลรามาธิบดี; มหาวิทยาลัยมหิดล. โรงพยาบาลรามาธิบดี. ฝ่ายการพยาบาล,the bowel pattern assessment form, and the constipation risk assessment form. Constipation wasevaluated by the frequency of defecation from the first to the fifth postoperative day, from 3 days beforesurgery to 5 days post operation, and the first day... was effective in reducing the incidence and severity ofconstipation. The program should be recommended as a tool to improve quality of care for hospitalizedelderly who are at risk of developing constipation.Publication Open Access Determinants of tobacco smoking among presumptive TB patients in Taungoo Township, Myanmar(2017) Kyaw Hsan Tun; Seo Ah Hong; Jiraporn Chompikul; จอ ซาน ตุน; โซ อะ หงษ์; จิราพร ชมพิกุล; Mahidol University. ASEAN Institute for Health Developmentwas drawn by purposive sampling were face-to-face interviewed using a structured questionnaire in April, 2017. The questionnaire had three parts: socio-demographic factors, socio-environmental factors and psycho-social factors based on social cognitive..., factors significantly associated with tobacco smoking were sex (Adj OR=4.65, 95%CI=2.14-10.12 for men compared to women), education levels (Adj OR=3.89, 95%CI=1.19-12.65 for middle or high school and Adj OR=4.39, 95%CI=1.22-15.77 for primary schoolPublication Open Access Inverse association of plasma IgG antibody to aggregatibacter actinomycetemcomitans and high C-reactive protein levels in patients with Metabolic Syndrome and Periodontitis.(2016-02-12) Supanee Thanakun; สุพานี ธนาคุณ; Suchaya Pornprasertsuk-Damrongsri; สุชยา ดำรงค์ศรี; Gokyu, Misa; Kobayashi, Hiroaki; Izumi, Yuichi; Mahidol University. Faculty of Dentistry. Department of Oral Medicine and Periodontology; Mahidol University. Faculty of Dentistry. Department of Oral and Maxillofacial RadiologyThe association between clinically diagnosed periodontitis, a common chronic oral infection, and metabolic syndrome has been previously reported. The aim of this study was to investigate the association of plasma IgG levels against Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, and Prevotella intermedia, C-reactive protein, and periodontal status with metabolic syndrome. Plasma IgG levels and C-reactive protein were measured by enzyme-linked immunosorbent assay, and salivary levels of A. actinomycetemcomitans and P. gingivalis were determined by quantitative real-time polymerase chain reaction. Among 127 individuals aged 35–76 years, 57 participants had metabolic syndrome and severe periodontitis, 25 had metabolic syndrome and an absence of severe periodontitis, 17 healthy individuals had severe periodontitis, and 28 healthy individuals were without severe periodontitis. Patients with metabolic syndrome had reduced humoral immune response to A. actinomycetemcomitans (p = 0.008), regardless of their salivary levels or periodontitis status compared with healthy participants. The IgG antibody response to P. gingivalis, regardless of their salivary levels or participants’ health condition, was significantly higher in severe periodontitis patients (p<0.001). Plasma IgG titers for P. intermedia were inconsistent among metabolic syndrome or periodontal participants. Our results indicate that the presence of lower levels of IgG antibodies to A. actinomycetemcomitans (OR = 0.1; 95%CI 0.0–0.7), but not P. gingivalis, a severe periodontitis status (OR = 7.8; 95%CI 1.1–57.0), high C-reactive protein levels (OR = 9.4; 95%CI 1.0–88.2) and body mass index (OR = 3.0; 95%CI 1.7–5.2), are associated with the presence of metabolic syndrome. The role of the decreased IgG antibody response to A. actinomycetemcomitans, increased C-reactive protein levels on the association between periodontal disease and metabolic syndrome in a group of Thai patients is suggested.Publication Open Access สภาวะสุขภาพและการปฏิบัติด้านสุขอนามัยส่วนบุคคลของผู้สูงอายุในศูนย์พัฒนาการจัดสวัสดิการสังคมผู้สูงอายุแห่งหนึ่ง กรุงเทพมหานคร(2554) ชนาณิศฐ์ อุประ; พิพัฒน์ ลักษมีจรัลกุล; พิศิษฐ์ วัฒนสมบูรณ์; ดุสิต สุจิรารัตน์; Pipat Luksamijarulkul; Pisit Vatanasomboon; Dusit Sujirarat; พิพัฒน์ ลักษมีจรัลกุล; มหาวิทยาลัยมหิดล. คณะสาธารณสุขศาสตร์. ภาควิชาจุลชีววิทยา; มหาวิทยาลัยมหิดล. คณะสาธารณสุขศาสตร์. ภาควิชาวิทยาศาสตร์อนามัยสิ่งแวดล้อม; มหาวิทยาลัยมหิดล. คณะสาธารณสุขศาสตร์. ภาควิชาระบาดวิทยาAging population is growing more rapidly in Asia including Thailand. Planning for social welfare development is important to increase the quality of life of elderly. The study of health status and personal hygiene practices among elderly in aPublication Open Access The neurological assessment in young children treated with artesunate monotherapy or artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria(2009) Ambler, Michael T.; Dubowitz, Lilly M.; Ratree Arunjerdja; Hla, Eh Paw; Thwai, Kyaw Lay; Viladpainguen, Jacher; Pratap Singhasivanon; ประตาป สิงหศิวานนท์; uxemburger, Christine; Nosten, François; McGready, Rose; McGready, Rose; Mahidol University. Faculty of Tropical Medicine. Mahidol-Oxford Tropical Medicine Research Unit (MORU)Background: Mefloquine and artesunate combination therapy is the recommended first-line treatment for uncomplicated malaria throughout much of south-east Asia. Concerns have been raised about the potential central nervous system (CNS) effects of both drug components and there are no detailed reports in very young children. Methods: Children, aged between three months and five years, with acute uncomplicated Plasmodium falciparum malaria were randomized to either 7 days of artesunate monotherapy or the same schedule of artesunate plus mefloquine on day 7 and 8. Neurological testing targeting coordination and behaviour was carried out at day 0, 7, 9, 10, 14 and 28. Nonfebrile healthy control children from the same population were tested on days 0, 7, 14 and 28. Results: From December 1994 to July 1997, 91 children with uncomplicated P. falciparum, 45 treated with artesunate monotherapy, 46 treated with mefloquine and artesunate combination therapy and 36 non-febrile controls, underwent neurological testing. Malaria and fever had a significant negative impact on testing performance. By contrast, the antimalarial treatments were not associated with worsening performances in the various components of the test. Artesunate and mefloquine do not appear to have a significant influence on coordination and behaviour. Children treated with mefloquine were significantly less likely to suffer recurrent malaria infection during follow-up compared to those treated with artesunate alone (P = 0.033). Conclusion: In keeping with the results of randomized controlled trials in adults, mefloquine was not associated with a decrease in specific items of neurological performance. Likewise, children treated with artesunate did not perform significantly differently to control children. This study does not exclude subtle or rare treatment CNS effects of artesunate or mefloquine. Treatment of acute uncomplicated malaria results in a significant improvement on items of neurological performance.