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Item Metadata only Neuro-Fuzzy based techniques for prediction of NPC recurrence(Mahidol University. Mahidol University Library and Knowledge Center, 2010) Orrawan Kumdee; Panrasee RitthiphavatPublication Metadata only Schwannoma Arising in Nasopharynx: A Case Report and Literature Review(2020-01-01) Kangsadarn Tanjararak; Navarat Tangbumrungtham; Sirithep Plumworasawat; Boonsam Roongpuvapaht; Faculty of Medicine, Ramathibodi Hospital, Mahidol University© 2020, Association of Otolaryngologists of India. Schwannoma in paranasal sinus has been known as a rare tumor in this origin. This study reports on primary schwannoma arising in the nasopharynx, which is an uncommon location. A 36-year-old female... at the nasopharynx extending inferiorly to the oropharynx. The tumor was excised via endoscopic combined trans-nasal/trans-oral approach under general anesthesia. The pathologic diagnosis was consistent with schwannoma. The tumor was successfully excised with enItem Metadata only Comparison of the dose distribution from cobalt-60 in spinal cord from different block techniques used for the treatment of nasopharyngeal carcinama(Mahidol University. Mahidol University Library and Knowledge Center, 1999) Chanida Phaettut; Ratana Pirabul; Charlee Kanistachart; Puangtong KraiphibulItem Metadata only Streptococcus pneumoniae Rapidly Translocate from the Nasopharynx through the Cribriform Plate to Invade the Outer Meninges(2022-08-01) Audshasai T.; Coles J.A.; Panagiotou S.; Khandaker S.; Scales H.E.; Kjos M.; Baltazar M.; Vignau J.; Brewer J.M.; Kadioglu A.; Yang M.; Mahidol Universitytranslocate from the nasopharynx to the dorsal meninges of a mouse in the absence of any bacteria found in blood or cerebrospinal fluid. Strikingly, this takes place within minutes of inhaled delivery of pneumococci, suggesting the existence of an inward flow... of fluid connecting the nasopharynx to the meninges, rather than a receptor-mediated mechanism. We also show that this process is size dependent, as microspheres of the same size as pneumococci can translocate along the same pathway, while larger sizePublication Metadata only Recovery of Cryptococcus neoformans from the nasopharynx of AIDS patients(1998-12-01) S. Sukroongreung; B. Eampokalap; S. Tansuphaswadikul; C. Nilakul; S. Tantimavanich; Mahidol University; Thailand Ministry of Public HealthNasopharyngeal swabbings, obtained from AIDS patients, were plated onto Niger seed agar containing antibiotics. Cryptococcus neoformans was isolated from 35 out of 84 patients (41.7%) diagnosed as primary cryptococcal cases before antifungal administration, and 8 out of 86 (9.3%) cryptococcosis patients on antifungal therapy. The fungus could not be isolated from any of 447 samples from 194 AIDS patients not diagnosed with cryptococcosis. These findings are novel in that the presence of C. neoformans in AIDS patients at this site has never been looked at previously.Item Metadata only A Pilot Study of 0.4% Povidone-Iodine Nasal Spray to Eradicate SARS-CoV-2 in the Nasopharynx(2022-01-01) Sirijatuphat R.; Leelarasamee A.; Puangpet T.; Thitithanyanont A.; Mahidol UniversityPurpose: This study aimed to evaluate the virucidal efficacy of 0.4% povidone-iodine (PVP-I) nasal spray against SARS-CoV-2 in the patients’ nasopharynx at 3 minutes and 4 hours after PVP-I exposure. Patients and Methods: The study was an open-labelPublication Metadata only Photodynamic therapy for residual or recurrent cancer of the nasopharynx(1999-11-01) Boonchu Kulapaditharom; Vipa Boonkitticharoen; Mahidol UniversityAdequate or effective treatments are not always available for most recurrent or residual nasopharyngeal cancers (NPC). Photodynamic therapy (PDT) using hematoporphyrin derivative (HpD) was evaluated for its effectiveness in treating patients, who conventionally failed, with curative or palliative intent. Thirteen patients were treated from March 1994 to November 1998. PDT was given to eradicate tumor cells, debulk tumor mass for other treatment options, and to resolve obstruction. Long-term tumor control could be achieved in 6 patients with localized lesions at T1-T2stages. The mean disease free survival time was 25.8 months (range 5-61 months). For tumors beyond T2stage (7 cases), PDT in combination with chemotherapy, laser surgery or radiotherapy induced complete response in 1 out of 5 patients (survival time = 40 months) and partial response in the rest (survival time = 16-37 months). In two patients who refused or were in tolerable to further treatment, PDT yielded useful palliative results (i.e. resolve nasal obstruction and epistaxis). On an overall basis, the average survival time for these patients with relatively advanced diseases was 24.7 months (range 9-40 months). Our study demonstrated that HpD-PDT could effectively control locally recurrent or residual NPC at T1-T2stages and offered good palliation for more advanced diseases. Combined PDT and chemotherapy seemed to prolong survival time for a period longer than 2 years in T3-T4tumors.Publication Metadata only LINE-1 methylation in the peripheral blood mononuclear cells of cancer patients(2012-05-18) Nakarin Kitkumthorn; Time Tuangsintanakul; Prakasit Rattanatanyong; Danai Tiwawech; Apiwat Mutirangura; Mahidol University; Faculty of Medicine, Chulalongkorn University; National Cancer Institute Thailandpatients and normal controls with a higher specificity and sensitivity than overall methylation levels. Here, we evaluated the LINE-1 methylation levels and patterns in PBMCs from patients with cancers of the nasopharynx, lung, liver, bile duct, breast... colorectal and nasopharyngeal cancer samples were found to have lower levels of overall LINE-1 methylation compared with normal controls (p < 0.0001 and p=0.0022). However, % u C u C in cancers of the colon, liver, lung and nasopharynx was significantlyPublication Metadata only MRI findings of the cavernous sinus metastasis with inferior extension mimicking a nasopharyngeal carcinoma with cavernous sinus invasion(2006-07-21) Laorporn Pawakranond; Jiraporn Laothamatas; Mahidol University; Faculty of Medicine, Ramathibodi Hospital, Mahidol UniversityThe authors report the MRI findings in a patient with cavernous sinus metastasis with inferior extension to the nasopharynx, mimicking imaging findings of the advanced nasopharyngeal cancer with the skull base, and intracranial extension. FindingsPublication Metadata only Isolation of influenza a virus in Reye's syndrome(1975-12-01) P. Visudhiphan; K. Chatiyanonda; Mahidol UniversityTwo cases of Reye's syndrome from Ramathibodi Hospital were reported. Both patients lived in the Bangkok area. They survived their illness after exchange blood transfusion. Influenza A virus was isolated from nasopharynx of case 1, and four fold