Publication: The role of apoB measurement in Type 2 diabetic patients
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Issued Date
2015-01-01
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ISSN
17584302
17584299
17584299
DOI
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2-s2.0-84928567440
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Mahidol University
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SCOPUS
Bibliographic Citation
Clinical Lipidology. Vol.10, No.2 (2015), 137-144
Suggested Citation
Brian Lee, Busadee Pratumvinit, Nuntakorn Thongtang The role of apoB measurement in Type 2 diabetic patients. Clinical Lipidology. Vol.10, No.2 (2015), 137-144. doi:10.2217/clp.15.6 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/36812
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Title
The role of apoB measurement in Type 2 diabetic patients
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Abstract
© 2015 Future Medicine Ltd. Aims: ApoB and non-HDL-C more accurately quantify cardiovascular risk than LDL-C; however, controversies exist over which is more clinically useful. We determined how well non-HDL-C targets predicted the attainment of apoB goals. Materials & Methods: In this cross-sectional study of Type 2 diabetic patients who achieved LDL-C <100 mg/dl, apoB and non-HDL-C concentrations, and the accuracy of non-HDL-C targets against apoB goals were determined. Results: Positive predictive values of non-HDL-C goals in predicting attainment of apoB goals were 90.3%, but were reduced in patients with hypertriglyceridemia or coronary heart disease (CHD). Conclusion: ApoB measurement could be useful in evaluating cardiovascular risk in diabetic subjects with hypertriglyceridemia or CHD who have already achieved LDL-C and non-HDL-C targets.