Scopus 2023
Permanent URI for this collectionhttps://repository.li.mahidol.ac.th/handle/123456789/81307
Browse
Recent Submissions
Item Metadata only Study the Physicochemical Property of Basil Mucilage Powder and Applying for Development of Weight Control Beverage(2023-05-01) Sangsuriyawong A.; Phongsrikun S.; Sinchaipanit P.; Peasura N.; Sirivarasai J.; Sangsuriyawong A.; Mahidol UniversityThe objective of this study was to analyze the physicochemical properties of basil mucilage for the development of weight control beverage. The extraction yield of the basil seed mucilage powder was about 15% by weight. Basil mucilage powder ( 100 g) contained 1. 65 g protein, 0. 82 g fat, 5. 22 g ash, 86. 5 g carbohydrates, and 5.8% moisture content. In addition, basil mucilage powder contained about 78% by weight of dietary fiber that was composed of about 21% soluble fiber and 57% insoluble fiber. Basil mucilage powder showed very high swelling property (40%), water holding value about 140 g/g, particle size range between 100-120 mesh, and 0. 25 of water activity. The result of microbiological analysis showed that total plate count was 6.6 x 103 CFU/g, Escherichia coli was less than 3 MPN/g, and Salmonella was not detected in 25 g of sample. The development of an orange flavor and sugar free beverage powder was further studied by using the extracted basil mucilage powder. A beverage formulation with the highest sensory acceptance score (n = 6, 5-points hedonic scale) contained 6 g basil mucilage powder, 1.5 g sorbitol, 0.045 g sucralose, 0.6 g citric acid, 0. 06 g salt, 0. 15 g orange flavor, and 0. 03 g of orange food coloring per 1 sachet or 1 serving size. A basil mucilage beverage product will be further studied the influence satiation in human studies.Item Metadata only Comparative Stem Anatomy of Some Dicotyledon Plants from 7 Families(2023-01-01) Singhakaew S.; Hamkrasri A.; Phaenark C.; Singhakaew S.; Mahidol UniversityThe objective of this research was to compare the anatomy of selected plant stems from different families. The specimens were 23 collected plant stems (3-4 species per each family) from 7 families (Amaranthaceae, Asteraceae, Cucurbitaceae, Euphorbiaceae, Leguminosae-Papilionoideae, Lamiaceae, and Piperaceae). The specimens were subjected to paraffin-based tissue preparation in preparation of permanent slides displaying cross-sections of stem tissue suitable for the study of arrangement of permanent tissues and vascular tissues in different plant stems using light microscopy. The results showed that sclerenchyma tissue arrangements were different in plants of different families, for example, in Asteraceae, the sclerenchyma forms clusters adjacent to the phloem structure. The sclerenchyma of Cucurbitaceae plants is circumferentially arranged in the cortex. In Piperaceae, the sclerenchyma is organized as a continuous band around the pit. The arrangement of the vascular tissues is also different in various families, for example, the vascular bundle spreads around the stem in the Asteraceae family. The vascular bundle penetrates into the pit of the Amaranthaceae and Piperaceae plants. While plants of the Cucurbitaceae family contain two groups of phloem (bicollateral bundle). Sclerenchyma and vascular organization, which are conserved in plants of the same family and distinctive from that of other families, can be exploited in identification and classification of the unknown plants. The unique tissue structures in the stem of plants from different family could also be fruitful for species identification, teaching and taxonomic studies.Item Metadata only Composition and Management Plan of the Hawker Solid Waste in Thewet Area, Bangkok(2023-09-01) Homsuwan T.; Kamnerdpetch C.; Sucharitkul S.; Homsuwan T.; Mahidol UniversityThis survey research aimed to study the waste composition, influence factors, and management guidelines for the solid waste generated from different types of hawkers in the Thewet area, Dusit District of Bangkok. It was found that there were 71 hawker stalls in the study area, including of 42 food stalls, 17 fruit/vegetable stalls, 5 beverage stalls, and 7 miscellaneous stalls. The average weight of waste generated was 181. 0 0 ± 7. 15 kilograms/day. The vast majority (84.23%) of the waste generated was organic waste, about 152.46 ± 7.15 kilograms/day, while the resalable waste and non-resalable waste were found in small amounts, which about 15.66 ± 0. 65 and 12. 88 ± 0. 29 kilograms/ day, respectively. It was also revealed that significant differences (95% confidence level, p<0.05) in waste composition were found in different types of hawkers, and during the long holiday periods. These findings highlighted that the study area needed more appropriate and effective waste management, consisting of (1) waste minimization and separation, (2) waste collection improvement and waste utilization according to the circular economy model, and (3) public-private-people participation. These results could be used for hawker waste management by the responsible agency, and be applied in similar areas to enhance sustainable tourism, along with eco-friendly development and growth.Item Metadata only Gait Analysis of Running and the Management of Common Injuries(2023-01-01) Hébert-Losier K.; Sinsurin K.; Hébert-Losier K.; Mahidol UniversityItem Metadata only Factors Associated with the Reporting of Incidents of Needlestick Injuries and Body Fluids Exposure among Clinical-Year Medical Students: A Cross-Sectional Analytical Study Performed at Siriraj Hospital(2023-07-01) Noosen P.; Wannarat N.; Koomanachai P.; Noosen P.; Mahidol UniversityIntroduction: Several studies and observational reports have highlighted the widespread underreporting of healthcare-associated injuries among healthcare personnel, especially medical students. Such underreporting can mask substandard medical practice and can lead to adverse complications if the injuries are not treated. The present study aimed to explore the reasons for the reporting and the factors associated with the non-reporting of needlestick injuries (NSIs) or exposure to a patient’s body substances among medical students in clinical practice. Method: Convenience-based sampling was used to collect data from medical student groups for a clinical research study. Questionnaires were distributed to 554 medical students studying at the clinical level in the Faculty of Medicine, Siriraj Hospital. The student responses were statistically analyzed via the frequency and percentages of the answers, as well as by chi-square test and Fisher's exact test. Results: Overall, 401 (72.38%) medical students completed and returned the questionnaire, comprising 192 (47.9%) male and 209 (52.1%) female students. Among these, 135 medical students in the 6th year of study stated they had experienced NSI (53%) or exposure to patients’ body substances (47%), although only 61% had reported such incidents. The most significant factor associated with the reporting of incidents was anxiousness about being infected (56.6%, p=0.02); while the injury type was the factor most associated with the non-reporting of incidents, especially when the injury was not considered serious and the risk of contagion was considered low (63.5%). Conclusion: The most important factor associated with the reporting or non-reporting of incidents was medical students’ concern about being infected from an incident. This reasoning though is inappropriate for monitoring medical practice. Safety guidelines for the management of injuries during medical practice need to be implemented and clarified for all medical students to ensure they are adhered to and that incidents are properly reported and managed. Further study should be carried out after implementing the guidelines for monitoring their effectiveness.Item Metadata only pWCP is a widely distributed and highly conserved Wolbachia plasmid in Culex pipiens and Culex quinquefasciatus mosquitoes worldwide(2023-12-01) Ghousein A.; Tutagata J.; Schrieke H.; Etienne M.; Chaumeau V.; Boyer S.; Pages N.; Roiz D.; Eren A.M.; Cambray G.; Reveillaud J.; Ghousein A.; Mahidol UniversityMosquitoes represent the most important pathogen vectors and are responsible for the spread of a wide variety of poorly treatable diseases. Wolbachia are obligate intracellular bacteria that are widely distributed among arthropods and collectively represents one of the most promising solutions for vector control. In particular, Wolbachia has been shown to limit the transmission of pathogens, and to dramatically affect the reproductive behavior of their host through its phage WO. While much research has focused on deciphering and exploring the biocontrol applications of these WO-related phenotypes, the extent and potential impact of the Wolbachia mobilome remain poorly appreciated. Notably, several Wolbachia plasmids, carrying WO-like genes and Insertion Sequences (IS), thus possibly interrelated to other genetic units of the endosymbiont, have been recently discovered. Here we investigated the diversity and biogeography of the first described plasmid of Wolbachia in Culex pipiens (pWCP) in several islands and continental countries around the world—including Cambodia, Guadeloupe, Martinique, Thailand, and Mexico—together with mosquito strains from colonies that evolved for 2 to 30 years in the laboratory. We used PCR and qPCR to determine the presence and copy number of pWCP in individual mosquitoes, and highly accurate Sanger sequencing to evaluate potential variations. Together with earlier observation, our results show that pWCP is omnipresent and strikingly conserved among Wolbachia populations within mosquitoes from distant geographies and environmental conditions. These data suggest a critical role for the plasmid in Wolbachia ecology and evolution, and the potential of a great tool for further genetic dissection and possible manipulation of this endosymbiont.Item Metadata only Influences of Compressive Strength and Casting Position on Flexural Strength of Polypropylene Fiber-Reinforced Self-Compacting Mortar(2023-07-01) Daungwilailuk T.; Kittikornjarus B.; Kitchanurak S.; Innchou T.; Attachaiyawuth A.; Daungwilailuk T.; Mahidol UniversityThis article presents the results on the effects of compressive strength, amount of polypropylene fiber and casting position on the flexural strength of polypropylene fiber-reinforced self-compacting mortar in order to identify suitable factors for using such a construction material. The results revealed that the compressive strength slightly improved (around 4%) when the fiber content was 1%. However, compressive strength decreased by 19% when the fiber content increased to 2%. The specimens in the present study had flexural strengths of around 6.0-6.4% of the compressive strengths of the mortar without fiber; flexural strength increased to 24% of compressive strength when the fiber content increased to 2% and when casting was performed at the middle of the beam. The flexural strength of the mortar significantly increased as the fiber content increased; the increase was approximately 33% and 90% as the fiber content increased to 1% and 2% by volume of the mortar. Casting position apparently affected the flexural strength. Pouring at the center of a beam resulted in 20% increase in the flexural strength. Because of the decrease in the compressive strength when the fiber content increased to 2%, polypropylene fiber-reinforced self-compacting mortar might not be suitable for compression members. On the other hand, such a mortar is appropriate for flexural members. The mortar would exhibit the best performance when casting is performed at the center of beam.Item Metadata only Trends in eczema prevalence in children and adolescents: A Global Asthma Network Phase I Study(2023-03-01) Langan S.M.; Mulick A.R.; Rutter C.E.; Silverwood R.J.; Asher I.; García-Marcos L.; Ellwood E.; Bissell K.; Chiang C.Y.; El-Sony A.; Ellwood P.; Marks G.B.; Mortimer K.; Elena Martínez-Torres A.; Morales E.; Perez-Fernandez V.; Robertson S.; Williams H.C.; Strachan D.P.; Pearce N.; Asher M.I.; Bissell K.; Chiang C.Y.; El-Sony A.; Ellwood E.; Ellwood P.; García-Marcos L.; Marks G.B.; Morales E.; Mortimer K.; Pearce N.; Masekela R.; Strachan D.P.; Perez-Fernández V.; Martinez-Torres A.; Robertson S.; Rutter C.E.; Silverwood R.J.; Mallol J.; Soto-Martinez M.E.; Cabrera Aguilar A.; Douros K.; Mohammed S.; Singh M.; Singh V.; Sukumaran T.U.; Awasthi S.; Kabra S.K.; Salvi S.; García-Almaráz R.; Mérida-Palacio J.V.; Del-Río-Navarro B.E.; González-Díaz S.N.; Navarrete-Rodriguez E.M.; Sánchez J.F.; Falade A.; Zar H.J.; López-Silvarrey Varela A.; González Díaz C.; Nour M.; Dib G.; Mohammad Y.; Huang J.L.; Chinratanapisit S.; Soto-Quirós M.E.; Vichyanond P.; Aguilar P.; Barba S.; Kumar L.; Sharma S.K.; Hanumante N.M.; Mérida-Palacio J.V.; Linares-Zapién F.J.; Onadeko B.O.; Musa O.A.A.; Aguirre V.; Baeza-Bacab M.; Mohammad S.; Cortéz E.; Gratziou C.H.; Chopra K.; Nelson H.; Rubio A.D.; Hsieh K.H.; Shah J.; Langan S.M.; Mahidol UniversityBackground: Eczema (atopic dermatitis) is a major global public health issue with high prevalence and morbidity. Our goal was to evaluate eczema prevalence over time, using standardized methodology. Methods: The Global Asthma Network (GAN) Phase I study is an international collaborative study arising from the International Study of Asthma and Allergies in Children (ISAAC). Using surveys, we assessed eczema prevalence, severity, and lifetime prevalence, in global centres participating in GAN Phase I (2015–2020) and one/ both of ISAAC Phase I (1993–1995) and Phase III (2001–2003). We fitted linear mixed models to estimate 10-yearly prevalence trends, by age group, income, and region. Results: We analysed GAN Phase I data from 27 centres in 14 countries involving 74,361 adolescents aged 13–14 and 47,907 children aged 6–7 (response rate 90%, 79%). A median of 6% of children and adolescents had symptoms of current eczema, with 1.1% and 0.6% in adolescents and children, respectively, reporting symptoms of severe eczema. Over 27 years, after adjusting for world region and income, we estimated small overall 10-year increases in current eczema prevalence (adolescents: 0.98%, 95% CI 0.04%–1.92%; children: 1.21%, 95% CI 0.18%–2.24%), and severe eczema (adolescents: 0.26%, 95% CI 0.06%–0.46%; children: 0.23%, 95% CI 0.02%–0.45%) with larger increases in lifetime prevalence (adolescents: 2.71%, 95% CI 1.10%–4.32%; children: 3.91%, 95% CI 2.07%–5.75%). There was substantial heterogeneity in 10-year change between centres (standard deviations 2.40%, 0.58%, and 3.04%), and strong evidence that some of this heterogeneity was explained by region and income level, with increases in some outcomes in high-income children and middle-income adolescents. Conclusions: There is substantial variation in changes in eczema prevalence over time by income and region. Understanding reasons for increases in some regions and decreases in others will help inform prevention strategies.Item Metadata only Foreign language reading anxiety: Exploring the experiences of EFL students at a state university in Padang, Indonesia(2023-04-28) Fitrawati; Kamil I.; Perrodin D.D.; Fitrawati; Mahidol UniversityThis study investigates the levels of foreign language reading anxiety among EFL students at a state university in Padang, West Sumatra, Indonesia, to identify the main factors contributing to this anxiety. The study included 30 participants who provided data through two questionnaires. The first questionnaire utilized the Foreign Language Reading Anxiety Scale (FLRAS) to assess anxiety levels, while the second questionnaire aimed to determine the primary factor behind this anxiety. The results indicated that 67% of the students experienced moderate anxiety, 20% experienced high levels, and 13% reported low anxiety. The study identified two main factors influencing foreign language reading anxiety: text features and personal factors. Text features encompassed unfamiliar vocabulary, topics, and culture, while personal factors included concerns about the effect of reading and fear of making errors. The second questionnaire revealed that unfamiliar language ranked as the most dominant factor, followed by concerns about the impact of reading, unfamiliar topics, fear of making errors, and unfamiliar culture. Recognizing that reading anxiety is a common experience among language learners is essential. However, with the proper support and guidance, students can overcome these challenges and succeed in their English language learning journey.Item Metadata only In vitro assessment of the pulmonary toxicity of particulate matter emitted during haze events in Chiang Mai, Thailand via investigation of macrophage responses(2023-06-01) Maciaszek K.; Gillies S.; Kawichai S.; Prapamontol T.; Santijitpakdee T.; Kliengchuay W.; Sahanavin N.; Mueller W.; Vardoulakis S.; Samutrtai P.; Cherrie J.W.; Brown D.M.; Tantrakarnapa K.; Johnston H.J.; Maciaszek K.; Mahidol UniversityChiang Mai (Thailand) experiences severe haze pollution in the dry season (December–April) each year mainly due to local and regional biomass burning (e.g. of agricultural land). A major component of the haze is airborne particulate matter (PM). During haze events, biomass burning is likely to be the dominant source of PM emissions, and at other times emissions from traffic dominate. The hazard of traffic derived PM has been extensively investigated previously but there are uncertainties regarding the toxicity of PM emitted from biomass burning. The toxicity of PM10 samples collected during and after haze events in Chiang Mai in 2020 was compared in vitro in J774.1 macrophages as they are responsible for the clearance of inhaled particles. Diesel exhaust particles and ultrafine carbon black were included as benchmark particles as they have been commonly used as a surrogate for PM. Cytotoxicity was evaluated 24 h post exposure at concentrations of 3.9–125µg ml−1. Cytokine production (tumour necrosis factor alpha (TNF-α), interleukin (IL)-6, IL-1β, macrophage inflammatory protein (MIP-2)) was assessed and cell morphology visualised using light and scanning electron microscopy. The hydrodynamic diameter, zeta potential and endotoxin content of all particles was assessed as well as the metal content of PM samples. All particles induced a concentration dependent decrease in cell viability and increased TNF-α and MIP-2 production. Only PM samples stimulated IL-6 production and only non-haze PM caused IL-1β production. No change in IL-10 production was detected for any particle. PM samples and DEP caused vacuole formation in cells. The concentrations of endotoxin and metals were highest in non-haze PM, which may explain why it induced the greatest inflammatory response. As non-haze PM was more toxic than haze PM, our results indicate that the source of PM emissions can influence its toxic potency and more specifically, that PM emitted from biomass burning may be less toxic than PM emitted from traffic.Item Metadata only Development of Calcium Enriched Bread with Asian Seabass Bone Powder(2023-05-01) Siangchin W.; Pangthai T.; Chaiya T.; Malai D.; Siangchin W.; Mahidol UniversityExtended Abstract Thailand is one of the countries with high aquaculture production, especially Asian seabass, and is the top exporter of processed fish. Aquaculture production tends to increase every year continuously for the past 10 years and it generates a lot of fish waste which gives value-added benefits both economically and environmentally. Fishbone is a source of calcium and which is biocalcium and contains up to 30-35 percent and is used as an alternative raw material in the production of calcium supplements and to create value-added products. However, the calcium in the fishbone is in the form of calcium phosphate, which is similar to the composition of human bones and teeth. It will make bones and teeth stronger. Osteoporosis is the second-highest public health problem in the world after heart disease and stroke. The main cause is a lack of calcium. Data have shown that calcium intake among Thai people is below the recommended amount and had a risk of osteoporosis as high as 90%, especially those aged 60 years and over. One approach to reducing this problem is to consume foods that are high in calcium. Bread is a bakery product that Thai people consume as a staple food. But bread is low in calcium, so the researchers were interested in adding more calcium to bread. The objective of the study was to determine the optimal ratio for the partial substitution of wheat flour with Asian seabass fishbone powder in bread for the enrichment of calcium. Fishbone powder was produced according to the fish biocalcium method and measured in physical and chemical properties. One of three bread formulas was selected based on their chemical, physical and sensory properties for bread making in this study. The ranking test was done by 30 students and staff of the Faculty of Public Health, Mahidol University, aged 21-26 years who like to eat bread. The substitution of fishbone powder was divided into 4 levels: 0, 1, 3, and 5%. The physical and chemical properties of the bread were measured. Fishbone powder contained moisture, fat, protein, ash, and calcium content of 4.10%, 0.13%, 0.4%, 88.59%, and 196.94 mg/g, respectively. The color value of fishbone powder was a high L* (lightness) value of 95.34 that higher than the L* of wheat. The a* value of-0.32 indicated a slight greenish hue. The b* value of 6.31 indicated a yellowish hue. Most of the 3 bread formulas had similar physical properties. But the sensory property of bread formula 2 was the most liked by the taste panel. Therefore, bread formula 2 was used in the next experiment. The increase of fishbone powder proportion increased the moisture, ash, and calcium content, density, and L* value while the protein, carbohydrate content, and specific volume decreased significantly (P <0.05) and also affected negatively the texture of the bread. There was no effect on a*, b*, weight loss, and the amount of free water. Bread with fishbone powder 0%, 1%, 3%, and 5% had calcium content of 11.29±0.53, 65.57+1.69, 180.86+1.68, and 267.15+10.89 mg/ 50 g, respectively. The 1% fishbone powder substitution could not be claimed nutritionally. But substitutions at 3%, and 5% can be nutritionally claimed as "High Calcium" or "Rich in Calcium". This study was approved by the Ethical Review Committee for Human Research Faculty of Public Health, Mahidol University (COA No. MUPH 2022-014).Item Metadata only Diagnostic accuracy of Opisthorchis viverrini antigen methods for human opisthorchiasis: Systematic review and Meta-analysis(2023-05-01) Maitongngam K.; Tipayamongkholgul M.; Kosaisavee V.; Maitongngam K.; Mahidol UniversityOpisthorchiasis relates to cholangiocarcinoma occurrences. Regular screening for Opisthorchis viverrini can prevent loss of human and economy; however, optimal screening techniques have not been identified. There are various methods to detect O. viverrin infections, and each method has its strengths and limitations. A common detection method, conventional fecal examinations are cheap but has high false-negative and cannot differentiate between O. viverrini and Minute intestinal fluke (MIF) eggs. Antigen detection can result in cross-reactivity with other helminths; nevertheless, it can detect O. viverrini at early stage of infection and uses non-invasive human samples. This systematic review and meta-analysis evaluated the diagnostic accuracy of antigen detection for O. viverrini. This research searched various databases: MEDLINE, EMBASE, Google scholar, PubMed, Scopus, Science direct, Cochrane, AMED, IPA, CINAHL, and Thai Thesis Database. Study selection and data extraction were done by two researchers independently. Of 142 published articles, 4 articles met the inclusion criteria. Quality assessment was done by QUADAS-2 and found a low risk of bias. Pooled sensitivity is 91 % (95% CI = 82%-96%) and pooled specificity is 68% (95% CI = 65%-72%). The high sensitivity of antigen detection for O. viverrini suggested its potential to be an optimal tool for early detection and treatment. However, the moderate specificity reflects lower effectiveness to apply the antigen test for surveillance in low endemic areas. The study's findings provide evidence of the precision of O. viverrini antigen detection. Public health decision-makers can employ antigen detection of O. viverrini as cost-effective screening tools in an epidemic area.Item Metadata only Factors Affecting Medication Adherence among Nepalese Hypertensives in a Rural Area(2023-09-01) Sharma S.; Chansatitporn N.; Jirapongsuwan A.; Timsina L.; Sharma S.; Mahidol UniversityMaintaining drug adherence has become a challenge for both the hypertensives and the health system for a variety of reasons. There is a lack of understanding about the several factors that may lead to medication non-adherence, especially among rural hypertensives. The purpose of this study was to assess the status of medication adherence and to identify the factors influencing medication adherence among Nepalese rural hypertensives. This community-based cross-sectional study was conducted among 405 rural hypertensives from Lamahi Municipality, Dang District of Nepal through a simple random sampling. The sample size for this study was determined using the formula: Z2pq/d2. The standard 9-items Hill-Bone medication scale (HB-MAS) questionnaire was used to assess the status of medication adherence. The questionnaires used in this study are based on rigorous literature review and were tested for the validity and reliability. Data was collected using a face-to-face interview and was analyzed using descriptive (frequency and proportion), bivariate (chi-square) and multiple logistic regression. Study indicated that only 56.5% hypertensives are adherent to antihypertensive medication. Ethnicity [adjusted odds ratio (AOR) = 0.24; 95% CI: 0.09-0.65, p 0.005], knowledge [AOR = 13.80; 95% CI: 4.95 – 38.48, p <0.001], attitude [AOR = 15.08; 95% CI: 5.21 – 43.63, p <0.001], availability of medication and services [AOR = 2.84; 95% CI: 1.24-6.49, p <0.013], and accommodation of hypertension-related services [AOR = 14.15; 95% CI: 2.21 – 90.57, p 0.005] are the factors associated with medication adherence. Targeting tailored interventions for specific ethnic groups, enhancing knowledge, and building trust among the hypertensives regarding the medication, ensuring availability of the antihypertensive medication, and strengthening current health service provision for antihypertensive medication and services closer to the communities might improve medication adherence among the rural hypertensives in Nepal.Item Metadata only Environmental Action is a Responsibility for a Viable Planet(2023-01-01) Charoenca N.; Charoenca N.; Mahidol UniversityItem Metadata only “Wellness” an Introduction to Concepts and Principles(2023-09-01) Pengpid S.; Pengpid S.; Mahidol UniversityItem Metadata only Factors Associated with Depression among Elderly in Mahalaxmi Municipality, Lalitpur, Nepal(2023-09-01) Shrestha G.S.; Kongsin S.; Jiamton S.; Siri S.; Shrestha G.S.; Mahidol UniversityDepression is a common mental health problem among the elderly, and its prevalence is increasing. This cross-sectional study aimed to assess the level of depression and the factors that contributed to depression. The study was conducted among 370 respondents aged 60 years and above obtained through multistage proportionate random sampling in Mahalaxmi Municipality, Lalitpur. Information was collected using a semi-structured questionnaire on socio-demogprahic factors, lifestyle factors, socio-economic factors, comorbid conditions, and depression using GDS-SF (Geriatric Depression Scale Short Form). Data were analyzed using descriptive and inferential methods (chi-square, binary logistic regression, and multiple logistic regression). The results showed a high prevalence of depression (53.2%). Multiple logistic regression identified several statistically significant factors. The elderly in the 70-79 age group were 2.05 times, and those aged 80 years and above were 1.81 times more likely to have depression than those aged 60-69 years. Similarly, low social support (AOR = 13.86, CI: 5.81-33.08), and low quality of life (AOR = 5.65, CI: 3.06-10.41) were statistically significant factors associated with depression. Hence, this study highlights the need for addressing depression among the elderly through targeted effective interventions and prioritizing elderly mental health care by policymakers.Item Metadata only Development of the High Alert Drug Management System in the Hospital for Tropical Diseases(2023-05-01) Saenglertsilpachai S.; Tapchaisri P.; Saenglertsilpachai S.; Mahidol UniversityExtended Abstract In a hospital, both pharmacists and nurses are mainly responsible for medications as prescribed by the physicians to the patients. Their skills and knowledge on medication administrations are crucial and needed to ensure that the patients will receive the appropriate, correct and safe medications. However, medication errors, although may rarely occur, may lead to inappropriate and undesirable consequences. The medication errors, which are preventable, are one of the important patient safety problems. The errors can happen at every stage of the medications including prescription, transcription, preparation, dispensing, administrating and/or monitoring of the patients. Many factors are involved in the medication errors. For examples, a weak medication system, the poor work conditions such as heavy workload of the personnel and the human factors such as fatigue or lack of medication knowledge. While any inappropriate medications can potentially cause harm to the patients, the errors involving the administrations of a group of selected drugs, so called the high-alert drugs (HAD), are frequently associated with the risks and the serious injuries of the patients. Even a minimal HAD mismanagement may cause the patient to have the serious adverse drug reactions. Additionally, HAD are most often prescribed to inpatients who are already predisposed to the severe illnesses. Therefore, the hospital policy and guidelines for health personnel in the administrations of HAD to the patients needed to be clear and precise. The Hospital for Tropical Diseases, Faculty of Tropical Medicine, is a 250-bed hospital with specialty in tropical and general medicine. Medication errors occurred in the hospital were rare but had the increasing tendency. Objectives of this study: 1) review on HAD and incidences of medical errors in the hospital; 2) develop the management system for drug monitoring and prevention of the medication errors; and 3) compare the incidences of the medical errors before and after the management system development. Methods: This research is a retrospective study involving collection of HAD usage data from the Hospital Information System installed in a personal computer and medication incidence reports from the cloud system of the hospital between October 1, 2018-September 30, 2020, before development of the drug management system and between October 1, 2020-September 30, 2022, after the development of the drug management system. The medication errors reported between the two periods were then compared. Results: There were 13 HAD items and 3 medication errors with one severe case of the patient reported during the first period. The drug management system involving HAD usage manual, HAD monitoring record form after drug administration and methods for accessing the HAD administration information were developed and implemented during the second period. It was found that 2 medical errors occurred but no severe case of the patient after the drug management system implementation. Conclusion: the HAD management system developed enables the medication administrators an easier and faster access to the HAD information than the previous system. The standard guidelines for HAD administration and monitoring system developed increase the patient safety and would reduce the incidence of medication errors in the future.Item Metadata only Family Resilience: A Concept for Coping with Family Crisis(2023-05-01) Thongworn S.; Thongworn S.; Mahidol UniversityThe purpose of this article is to present the concept of family resilience in terms of the origins of the concept development, the main concept, and the key processes of the concept. Family resilience is the family's ability to endure, adapt, change, and capacity to bounce back to normality even when encountering problems, obstacles, or various crises with stability and strength. The important processes that lead to family resilience consist of three important processes, namely the process of belief systems, organizational patterns, communication and problem-solving. Although the family resilience concept has received widespread attention abroad, in Thailand, it was found that the concept of family resilience has been very rarely applied in research studies on family crisis issues, and it is often studied at the individual level, therefore, it is not widely known among researchers in Thailand. Understanding the concept of family resilience can help those who are interested in this idea to use it as an alternative approach to research studies or to develop further family promotion interventions and programs.Item Metadata only Factors Associated with Mammograms and Pap Smears Screening: A National Survey in Thailand(2023-09-01) Chongthawonsatid S.; Chongthawonsatid S.; Mahidol UniversityDuring the COVID-19 epidemic, the accessibility of healthcare facility services was disrupted. This study examined factors associated with having mammograms and Pap smear screenings during the COVID-19 epidemic in Thailand. The study was based on the 2021 Health and Welfare Survey of the Thai National Statistical Office. Skilled interviewers systematically conducted population-based surveys. They polled 11,078,970 women aged 40 or older regarding mammographic screening for breast cancer and 13,460,390 women aged 30 or older about Pap screening for cervical cancer. The independent variables were age, religion, education, occupation, income, healthcare-cost coverage, geographic region, and domicile location. The two dependent variables were mammograms and Pap smears. Univariate and multiple binary logistic regression analyses were performed to identify the factors associated with mammograms for breast cancer and Pap smears for cervical cancer. Results found that cancer screening rates via mammograms and Pap smears decreased during COVID-19 in Thailand. The women who had mammograms and Pap smear screenings were 13.8% and 54.0%, respectively. The primary reason for not undergoing screening was the women’s belief that they did not have any abnormalities in their breasts (64.5%) or cervix (53.1%). Some women were unaware that breast cancer could be screened via mammography (19.2%), while 22.7% believed that Pap smear screening for cervical cancer was unnecessary. Binary logistic regression analyses found that the factors associated with having mammograms and Pap smears were demographic, socioeconomic, geographic, healthcare-cost coverage, and economic status. The Thai government could conduct information campaigns to educate women about the need for breast and cervical cancer screening via mammograms and Pap smears, especially among at-risk populations.Item Metadata only Factors Predicting Preventive Behaviors of Coronavirus Disease 2019 Infection Among Older Adults in Rayong Province(2023-05-01) Juntakot N.; Boonyamalik P.; Kerdmongkol P.; Rawiworrakul T.; Juntakot N.; Mahidol UniversityExtended Abstract Coronavirus disease 2019 is characterized as a global pandemic that caused millions of infections and deaths worldwide. Particularly, the elderly with age-related deterioration and chronic disease are more vulnerable to be infected and death. This Cross-sectional study aimed to investigate the preventive behaviors of Coronavirus Disease 2019 and its predictive factors among older adults in Rayong province applying the PRECEDE – PROCEED model. The study samples were 420 elderly aged 60 and older recruited by using multistage sampling technique. Data were collected using interviewed questionnaire. Descriptive and inferential statistics such as Spearman Rank Correlation, Chi-square, and Multiple Logistic Regression analysis were applied for data analysis. The results showed that the sample had a mean age of 66.9 years old. Most of them were female (62.9%), living in industrial area (59.0%), with good level of preventive behaviors of Coronavirus Disease 2019 (Mean = 34.05, SD. = 3.415). Factors significantly associated with preventive behaviors (p <0.05) were; Predisposing factors (sex, marital status, residential area, perceived susceptibility, perceived severity, perceived barriers, perceived benefits), enabling factors, and reinforcing factors. Multiple logistic regression revealed that the elderly who were female (p <0.05), living in industrial area (p <0.0001), having better perceived severity (p <0.0001), and receiving reinforcing factors (p <0.0001) were more likely to have appropriate preventive behaviors. All these factors could explain the variance of the preventive behavior by 11.8% with a predictive accuracy of 51.0%. These findings can be used as a guideline for further developing a plan for surveillance, prevention, and control of Coronavirus disease 2019 among the elderly in the community especially for the elderly in the industrial area.