Publication: Calcium-phosphorus homeostasis in cats with spontaneous chronic kidney disease and metabolic acidosis
Issued Date
2012-01-01
Resource Type
ISSN
1618565X
16185641
16185641
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2-s2.0-84867089203
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Mahidol University
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SCOPUS
Bibliographic Citation
Comparative Clinical Pathology. Vol.21, No.5 (2012), 985-991
Suggested Citation
Rosama Pusoonthornthum, Onrassamee Vimuktanandana, Pinit Pusoonthornthum, Anudep Rungsipipat, Nateetip Krishnamra Calcium-phosphorus homeostasis in cats with spontaneous chronic kidney disease and metabolic acidosis. Comparative Clinical Pathology. Vol.21, No.5 (2012), 985-991. doi:10.1007/s00580-011-1213-8 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/15041
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Title
Calcium-phosphorus homeostasis in cats with spontaneous chronic kidney disease and metabolic acidosis
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Abstract
The effect of metabolic acidosis on calcium-phosphorus homeostasis in cats with spontaneous chronic kidney disease (CKD) was studied. The cats were assigned into the clinically normal cats (n = 6), CKD (n = 9), and CKD with metabolic acidosis (12 cats). The CKD cats were cats with a blood urea nitrogen ≥50 mg/dl and creatinine level ≥2. 1 mg/dl. A complete blood count, sodium, potassium, total calcium, adjusted calcium, ionized calcium, phosphorus, parathyroid hormone, and vitamin D levels were measured. The cats with spontaneous CKD had a significantly lower hemoglobin and pack cell volume than the clinically normal cats. The CKD cats with metabolic acidosis had mean creatinine levels of 7. 12 ± 0. 76 mg/dl (severe azotemic stage) and significantly increased levels of parathyroid hormone and plasma phosphorus levels which indicated the presence of renal secondary hyperparathyroidism. © 2011 Springer-Verlag London Limited.