In vitro suppression on development of plasmodium falciparum in thalassemic erythrocytes by oxidative stress
2
Issued Date
1988
Copyright Date
1988
Resource Type
Language
eng
File Type
application/pdf
No. of Pages/File Size
ix, 103 leaves : ill.
Access Rights
open access
Rights
ผลงานนี้เป็นลิขสิทธิ์ของมหาวิทยาลัยมหิดล ขอสงวนไว้สำหรับเพื่อการศึกษาเท่านั้น ต้องอ้างอิงแหล่งที่มา ห้ามดัดแปลงเนื้อหา และห้ามนำไปใช้เพื่อการค้า
Rights Holder(s)
Mahidol University
Bibliographic Citation
Thesis (M.Sc. (Microbiology))--Mahidol University, 1988
Suggested Citation
Jamaree Bhisutthibhand In vitro suppression on development of plasmodium falciparum in thalassemic erythrocytes by oxidative stress. Thesis (M.Sc. (Microbiology))--Mahidol University, 1988. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/103276
Title
In vitro suppression on development of plasmodium falciparum in thalassemic erythrocytes by oxidative stress
Alternative Title(s)
การยับยั้งการเจริญเติบโตของเชื้อมาเลเรียในเม็ดเลือดแดงของคนที่เป็น & thalassemia trait เมื่ออยู่ในสภาวะ oxidative stress
Author(s)
Advisor(s)
Abstract
This study is aimed at investigating the effect of oxidative stress on the development of Plasmodium falciparum in ?-thalassemia erythrocytes in vitro. P. falciparum cultured in erythrocytes from normal (n = 16), ?-thalassemia 1 trait (n = 20), ?-thalassemia 2 trait (n = 10), Hb CS trait (n = 8) was subjected to H(,2)O(,2), generated from the reaction of glucose-glucose oxidase. Results from experiments revealed that malaria parasite in ?-thalassemia 2 trait and Hb CS trait erythrocytes were more susceptible to H(,2)O(,2) than that in ?-thalassemia 1 trait which was not significantly different from normal erythrocyte. The reduction of parasite survival was more pronounced when the thalassemia sera were used.
Description
Microbiology (Mahidol University 1988)
Degree Name
Master of Science
Degree Level
Master's degree
Degree Department
Faculty of Science
Degree Discipline
Microbiology
Degree Grantor(s)
Mahidol University