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Publication Open Access Significant association between vitamin D deficiency and sepsis: a systematic review and meta-analysis(2015) Sikarin Upala; Anawin Sanguankeo; Nitipong Permpalung; Mahidol University. Faculty of Medicine Siriraj Hospital. Department of Preventive and Social Medicinebetween patients with vitamin D deficiency and controls. Results: The initial search yielded 647 articles. Twenty-one articles underwent full-length review and data were extracted from 10 observational studies. Pooled odds ratio of sepsis in participants... with vitamin D deficiency was 1.78 (95 % confidence interval [CI] = 1.55 to 2.03, p < 0.01) compared with controls in studies that reported participant numbers and was 1.45 (95 % CI = 1.26 to 1.66, p < 0.01) in studies that reported an adjusted odds ratioPublication Open Access Hypovitaminosis D in healthy children in Central Thailand: prevalence and risk factors(2015) Kanit Reesukumal; Kotchamol Manonukul; Orathai Jirapongsananuruk; Wijittra Krobtrakulchai; Sithikan Hanyongyuth; Somruedee Chatsiricharoenkul; Busadee Pratumvinit; Mahidol University. Faculty of Medicine Siriraj Hospital. Department of Clinical Pathology)D was 64.0 ± 15.1 nmol/L. Hypovitaminosis D (< 75 nmol/L) was presented in 79.2% of subjects. Of these, the prevalence of vitamin D insufficiency and vitamin D deficiency were 59.7% and 19.5%, respectively. In univariate analysis, children... with hypovitaminosis D (< 75 nmol/L) had a higher mean body mass index (BMI) percentile than the vitamin D-sufficient group (56.7 ± 33.9 vs. 42.6 ± 36.0; P-value = 0.04). Plasma PTH levels in the children with hypovitaminosis D were significantly higher thanPublication Open Access Mineral metabolism and outcomes in chronic kidney disease stage 2–4 patients(2013) Kamonwan Chartsrisak; Kotcharat Vipattawat; Montira Assanatham; Arkom Nongnuch; Atiporn Ingsathit; Somnuek Domrongkitchaiporn; Vasant Sumethkul; Sinee Distha-Banchong; Mahidol University. Faculty of Medicine Ramathibodi Hospital. Division of NephrologyBackground: Marked hyperphosphatemia, hyperparathyroidism and 25-hydroxyvitamin D deficiency are associated with mortality in dialysis patients. Such data in chronic kidney disease stage 2–4 population are limited. It has been suggested that high... and the patients were followed prospectively for 25 (1–44) months or until they reached the endpoints of end-stage renal disease or mortality. Results: Hyperparathyroidism and 25-hydroxyvitamin D deficiency began to occur in the early stages of chronic kidneyPublication Open Access Discrepant association of serum C-3 epimer of 25-hydroxyvitamin D versus non-epimeric 25-hydroxyvitamin D with serum lipid levels(2016) La-or Chailurkit; Wichai Aekplakorn; Kriangsuk Srijaruskul; Boonsong Ongphiphadhanakul; Mahidol University. Ramathibodi Hospital. Department of MedicineBackground: Low vitamin D status has been associated with a number of chronic diseases. For dyslipidemia, vitamin D deficiency has been associated with higher low density lipoprotein-cholesterol (LDL-C) in a number of studiesPublication Open Access Relationship of vitamin D status and bone mass according to vitamin D-binding protein genotypes(2015) Hataikarn Nimitphong; Chanika Sritara; La-or Chailurkit; Suwannee Chanprasertyothin; Wipa Ratanachaiwong; Piyamitr Sritara; Boonsong Ongphiphadhanakul; Mahidol University. Faculty of Medicine Ramathibodi Hospital. Department of Medicine and Research CenterBackground: Vitamin D-binding protein (DBP) may alter the biological activity of total 25-hydroxyvitamin D [25(OH)D]; this could influence on the effects of vitamin D in relation to bone mineral density (BMD) and fractures. Emerging data suggest... that fetuin-A may be involved in bone metabolism. We aimed to investigate the influence of DBP gene polymorphism on the relationship of vitamin D status and fetuin-A levels to BMD and bone markers. Methods: This cross-sectional study was part of a healthPublication Open Access Clinically unapparent infantile thiamin deficiency in Vientiane, Laos.(2011-02-22) Khounnorath, Sengmanivong; Chamberlain, Karen; Taylor, Ann M.; Soukaloun, Douangdao; Mayxay, Mayfong; Lee, Sue J.; Phengdy, Bounthom; Luangxay, Khonsavanh; Sisouk, Kongkham; Soumphonphakdy, Bandit; Latsavong, Khaysy; Akkhavong, Kongsin; White, Nicholas J.; Newton, Paul N.; Newton, Paul N.; Mahidol University. Faculty of TropicalMedicine. Mahidol-Oxford Tropical Medicine Research Unit.BACKGROUND: Beriberi occurs in Vientiane, Lao PDR, among breastfed infants. Clinical disease may be the tip of an iceberg with subclinical thiamin deficiency contributing to other illnesses. Thiamin treatment could improve outcome. METHODOLOGY.../PRINCIPAL FINDINGS: A cohort of 778 sick infants admitted during one year without clinical evidence of beriberi were studied prospectively and erythrocyte transketolase assays (ETK) performed. Biochemical thiamin deficiency was defined both in termsPublication Open Access The Association of vitamin D status and fasting glucose according to body fat mass in young healthy Thais(2013) Hataikarn Nimitphong; La-or Chailurkit; Suwannee Chanprasertyothin; Piyamitr Sritara; Boonsong Ongphiphadhanakul; Mahidol University. Ramathibodi Hospital. Faculty of MedicineBackground: Existing inconclusive data on the relationship between vitamin D status and human glucose homeostasis suggests that other factors, such as adiposity, might influence this relationship. The present study aimed to investigate... and controlled for age and gender, there was a positive, although weak association between 25(OH)D levels and FPG (p = 0.01) in the lowest tertile. Conclusions: We therefore speculate that adiposity might influence the relationship of vitamin D status and FPG.Publication Open Access Prevalence of Vitamin D insufficiency and low bone mineral density in elderly Thai nursing home residents(2012) Anuk Kruavit; La-or Chailurkit; Ammarin Thakkinstian; Chutintorn Sriphrapradang; Rajata Rajatanavin; Mahidol University. Faculty of Medicine Ramathibodi Hospital. Department of MedicineBackground: Numerous emerging data from research on osteoporosis among Asians found differences from Caucasians. Therefore, the aim of this study was to determine the prevalence of vitamin D insufficiency and osteoporosis in elderly participants.... Vitamin D insufficiency was defined as 25(OH)D level < 70 nmol/l. Results: The mean age of subjects was 75.2 ± 6.0 (SD) years. Dietary calcium intake was low (322 ± 158 mg/day) The mean 25(OH)D level was 64.3 ± 14.9 nmol/L and the prevalence of vitamin DPublication Open Access Estrogen Deficiency Leads to Further Bone Loss in the Mandible of CKD Mice.(2016-02-17) Dutmanee Seriwatanachai; ดุษมณี เสรีวัฒนาชัย; Guo, Yuchen; Sun, Ningyuan; Duan, Xiaobo; Xu, Xin; Zheng, Liwei; Wang, Yongyue; Yuan, Quan; Mahidol University. Faculty of Dentistry. Department of Oral Biologyimplants. The aim of this study was to investigate the effects of estrogen deficiency on the mandibular bone in CKD mice. METHODS: Forty eleven-week-old female C57BL mice were used in this study. Uremia and estrogen deficiency were induced by 5/6... that estrogen deficiency leads to further mandibular bone loss in CKD mice.Publication Open Access Regional variation and determinants of vitamin D status in sunshine-abundant Thailand(2011) La-or Chailurkit; Wichai Aekplakorn; Boonsong Ongphiphadhanakul; Mahidol University. Ramathibodi Hospital. Department of MedicineBackground: Vitamin D insufficiency is highly prevalent. Most of the studies concerning vitamin D status were generated from countries situated at temperate latitudes. It is less clear what the extent of vitamin D insufficiency is in countries... situated in the tropics and how geographical regions within country would affect vitamin D status. In the present study, we investigated vitamin D status in Thais according to geographical regions and other risk factors. Methods: Subjects consisted of 2
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