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Publication Open Access Significant association between vitamin D deficiency and sepsis: a systematic review and meta-analysis(2015) Sikarin Upala; Anawin Sanguankeo; Nitipong Permpalung; Mahidol University. Faculty of Medicine Siriraj Hospital. Department of Preventive and Social Medicinebetween patients with vitamin D deficiency and controls. Results: The initial search yielded 647 articles. Twenty-one articles underwent full-length review and data were extracted from 10 observational studies. Pooled odds ratio of sepsis in participants... with vitamin D deficiency was 1.78 (95 % confidence interval [CI] = 1.55 to 2.03, p < 0.01) compared with controls in studies that reported participant numbers and was 1.45 (95 % CI = 1.26 to 1.66, p < 0.01) in studies that reported an adjusted odds ratioPublication Open Access The Association of Vitamin D Level and Pulmonary Tuberculosis in Thailand(2016) Viratch Tangsujaritvijit; Pichaya Chamnanve; Chalalai Klaipim; Naparat Amornputtisathaporn; วิรัช ตั้งสุจริตวิจิตร; พิชญา ชำนาญเวช; ชลาลัย คล้ายพิมพ์; นภารัตน์ อมรพุฒิสถาพร; Mahidol University. Faculty of Medicine Ramathibodi Hospital. Department of Medicine; Chaophraya Abhaibhubejhr HospitalBackground: About ten million of the world population has vitamin D deficiency The associations between vitamin D deficiency and tuberculosis (TB) may be explained by evidence for an immunoregulatory role of the vitamin. A previous study has shown... that polymorphisms in vitamin D receptor associated with TB infection in some population and in some studies showed the association of vitamin D deficiency with pulmonary TB as the risk factor. In Thailand, there has been no prior study about the association betweenPublication Open Access Hypovitaminosis D in healthy children in Central Thailand: prevalence and risk factors(2015) Kanit Reesukumal; Kotchamol Manonukul; Orathai Jirapongsananuruk; Wijittra Krobtrakulchai; Sithikan Hanyongyuth; Somruedee Chatsiricharoenkul; Busadee Pratumvinit; Mahidol University. Faculty of Medicine Siriraj Hospital. Department of Clinical Pathology)D was 64.0 ± 15.1 nmol/L. Hypovitaminosis D (< 75 nmol/L) was presented in 79.2% of subjects. Of these, the prevalence of vitamin D insufficiency and vitamin D deficiency were 59.7% and 19.5%, respectively. In univariate analysis, children... with hypovitaminosis D (< 75 nmol/L) had a higher mean body mass index (BMI) percentile than the vitamin D-sufficient group (56.7 ± 33.9 vs. 42.6 ± 36.0; P-value = 0.04). Plasma PTH levels in the children with hypovitaminosis D were significantly higher thanPublication Open Access Association Between Vitamin D Levels and Vitamin D Receptor FokI Polymorphism in Thai Postmenopausal Women With Osteoporosis(2021) Napatsanant Rojanasrirat; Somsak Suthutvoravut; Pattamawadee Yanatatsaneejit; Anna Wongkularb; นภัสนันท์ โรจนาศรีรัตน์; สมศักดิ์ สุทัศน์วรวุฒิ; ปฐมวดี ญาณทัศนีย์จิต; แอนนา วงษ์กุหลาบ; Mahidol University. Faculty of Medicine Ramathibodi Hospital. Department of Obstetrics and Gynecologythe groups (P > .05). However, the TT genotype of VDR FokI polymorphism was significantly associated with vitamin D deficiency (< 20 ng/mL) (OR, 6.15; 95% CI, 1.51 - 25.14; P < .05). Conclusions: Vitamin D levels and genotype of VDR FokI polymorphisms were... similar between the osteoporotic and non-osteoporotic postmenopausal women. The TT genotype of VDR FokI polymorphism showed a significant association with vitamin D deficiency. Therefore, TT genotype of VDR FokI polymorphism may be used to predict riskPublication Open Access Triple-fortified rice containing vitamin A reduced marginal vitamin A deficiency and increased vitamin A liver stores in school-aged Thai children.(2014) Siwaporn Pinkaew; Rita Wegmuller; Emorn Wasantwisut; Pattanee Winichagoon; Hurrell, Richard F.; Tanumihardjo, Sherry A.; Mahidol University. Institute of NutritionVitamin A (VA)-fortified rice is a potential intervention strategy to prevent VA deficiency in at-risk populations. Hot-extruded, triple-fortified rice grains with added VA, zinc, and iron were produced by hot extrusion technology and their abilityPublication Open Access Mineral metabolism and outcomes in chronic kidney disease stage 2–4 patients(2013) Kamonwan Chartsrisak; Kotcharat Vipattawat; Montira Assanatham; Arkom Nongnuch; Atiporn Ingsathit; Somnuek Domrongkitchaiporn; Vasant Sumethkul; Sinee Distha-Banchong; Mahidol University. Faculty of Medicine Ramathibodi Hospital. Division of NephrologyBackground: Marked hyperphosphatemia, hyperparathyroidism and 25-hydroxyvitamin D deficiency are associated with mortality in dialysis patients. Such data in chronic kidney disease stage 2–4 population are limited. It has been suggested that high... and the patients were followed prospectively for 25 (1–44) months or until they reached the endpoints of end-stage renal disease or mortality. Results: Hyperparathyroidism and 25-hydroxyvitamin D deficiency began to occur in the early stages of chronic kidneyPublication Open Access Discrepant association of serum C-3 epimer of 25-hydroxyvitamin D versus non-epimeric 25-hydroxyvitamin D with serum lipid levels(2016) La-or Chailurkit; Wichai Aekplakorn; Kriangsuk Srijaruskul; Boonsong Ongphiphadhanakul; Mahidol University. Ramathibodi Hospital. Department of MedicineBackground: Low vitamin D status has been associated with a number of chronic diseases. For dyslipidemia, vitamin D deficiency has been associated with higher low density lipoprotein-cholesterol (LDL-C) in a number of studiesPublication Open Access Relationship of vitamin D status and bone mass according to vitamin D-binding protein genotypes(2015) Hataikarn Nimitphong; Chanika Sritara; La-or Chailurkit; Suwannee Chanprasertyothin; Wipa Ratanachaiwong; Piyamitr Sritara; Boonsong Ongphiphadhanakul; Mahidol University. Faculty of Medicine Ramathibodi Hospital. Department of Medicine and Research CenterBackground: Vitamin D-binding protein (DBP) may alter the biological activity of total 25-hydroxyvitamin D [25(OH)D]; this could influence on the effects of vitamin D in relation to bone mineral density (BMD) and fractures. Emerging data suggest... that fetuin-A may be involved in bone metabolism. We aimed to investigate the influence of DBP gene polymorphism on the relationship of vitamin D status and fetuin-A levels to BMD and bone markers. Methods: This cross-sectional study was part of a healthPublication Open Access Clinically unapparent infantile thiamin deficiency in Vientiane, Laos.(2011-02-22) Khounnorath, Sengmanivong; Chamberlain, Karen; Taylor, Ann M.; Soukaloun, Douangdao; Mayxay, Mayfong; Lee, Sue J.; Phengdy, Bounthom; Luangxay, Khonsavanh; Sisouk, Kongkham; Soumphonphakdy, Bandit; Latsavong, Khaysy; Akkhavong, Kongsin; White, Nicholas J.; Newton, Paul N.; Newton, Paul N.; Mahidol University. Faculty of TropicalMedicine. Mahidol-Oxford Tropical Medicine Research Unit.BACKGROUND: Beriberi occurs in Vientiane, Lao PDR, among breastfed infants. Clinical disease may be the tip of an iceberg with subclinical thiamin deficiency contributing to other illnesses. Thiamin treatment could improve outcome. METHODOLOGY.../PRINCIPAL FINDINGS: A cohort of 778 sick infants admitted during one year without clinical evidence of beriberi were studied prospectively and erythrocyte transketolase assays (ETK) performed. Biochemical thiamin deficiency was defined both in termsPublication Open Access The Association of vitamin D status and fasting glucose according to body fat mass in young healthy Thais(2013) Hataikarn Nimitphong; La-or Chailurkit; Suwannee Chanprasertyothin; Piyamitr Sritara; Boonsong Ongphiphadhanakul; Mahidol University. Ramathibodi Hospital. Faculty of MedicineBackground: Existing inconclusive data on the relationship between vitamin D status and human glucose homeostasis suggests that other factors, such as adiposity, might influence this relationship. The present study aimed to investigate... and controlled for age and gender, there was a positive, although weak association between 25(OH)D levels and FPG (p = 0.01) in the lowest tertile. Conclusions: We therefore speculate that adiposity might influence the relationship of vitamin D status and FPG.