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Item Open Access Effectiveness and risk-benefit analysis of urate lowering therapy in asymptomatic hyperuricemia : a real-world study(Mahidol University. Mahidol University Library and Knowledge Center, 2021) Tunlanut Sapankaew; Atiporn Ingsathit; Kunlawat Thadanipon; Ammarin ThakkinstianHyperuricemia was associated with a higher risk of multiple chronic diseases. Several studies were conducted on urate-lowering therapy agents (ULT) in asymptomatic hyperuricemia, whereas few studies focused on clinical outcomes of cardiovascular events, and as such the treatment effects of ULT on clinical outcomes were inconclusive. Retrospective 10-year observational study (2010 to 2020) was conducted, using electronic medical records of Ramathibodi Hospital of patients with asymptomatic hyperuricemia, who were free of major adverse cardiovascular event (MACE), i.e., acute myocardial infarction, cerebrovascular accident, and cardiovascular death, and renal replacement therapy (RRT) at inception and prescribed with or without any ULT. The interested outcomes were occurrence of MACE, initiation of RRT, progression of chronic kidney disease (CKD), relative changes of estimated glomerular filtration rate (eGFR), serum urate level. The analyses were performed through conventional covariate adjustment and counterfactual approaches. Moreover, risk-benefit analysis was performed to identify the optimal treatment. A total of 23838 patients with asymptomatic hyperuricemia were identified, including 2251 patients in xanthine oxidase inhibitor (XOI) drugs (allopurinol and febuxostat), 150 patients in uricosuric drugs (probenecid, benzbromarone, and sulfinpyrazone), and 21437 patients in no-ULT groups. With conventional covariate adjustment, this study found protective effect of XOI drugs when compared with no-ULT group with adjusted hazard ratios (HR) (95% confidence interval [CI]) of XOI drugs were 0.84 (0.74, 0.96) for MACE prevention, 0.73 (0.56, 0.96) for RRT initiation, and 0.91 (0.83, 0.99) for CKD progression whereas these were not found in uricosuric drugs. By counterfactual approach, preventive effects on MACE, RRT, and CKD progression by XOI as compared to no-ULT were non-significant, whereas XOI resulted in significant higher of eGFR than no-ULT with average treatment effects (95% CI) of 3.27 (2.04, 4.50). Percentage of cardioprotective and renoprotective effects would be higher if clinicians accepted the severe hypersensitivity to be more than 3 and 4 out of 1000 patients, respectively. This real-world evidence suggested that administering XOI drugs in patients of asymptomatic hyperuricemia could lower the risk of developing MACE, RRT initiation, and CKD progression with higher of eGFR compared with no-ULT, whereas these preventive effects were not shown with uricosuric drugs.Item Open Access Analysis of amphetamine drug trafficking patterns in Thailand(Mahidol University. Mahidol University Library and Knowledge Center, 2022) Wichit Yaemyim; Sunee Kanyajit; Veenunkarn Rujiprak; Suppakorn Poonyarith; Thomas GuadamuzThe widespread use of amphetamine drugs, especially methamphetamine (Ya ba) and ice, continues to increase as shown in the statistics and trends of offenses. Additionally, the development of trafficking patterns is more advanced than the government prevention and suppression measures. The purposes of this research were (1) to study situations of widespread use and trafficking patterns of amphetamine drugs, especially methamphetamine (Ya ba) and ice, and (2) to suggest guidelines to develop effective measures of amphetamine drug suppression in Thailand. A qualitative research method was employed in this research using unstructured interviews with 30 informants. Data from in-depth interviews were conducted and analyzed using content analysis. The results revealed that the current situation of amphetamine drug trafficking where political unrest of neighboring countries and the COVID-19 pandemic occurred was not likely to decrease. The research also found that transport routes to the northeastern borders were frequently selected. The transportation to third countries was through land, cargo ships, air, and international postal services. The aforementioned international trafficking patterns were conducted through a large network with comprehensive measures to prevent tracking down of key figures at various levels by cutting off all interactions. In the meantime, domestic trafficking patterns employed modern technology to avoid official inspection and monitoring. Consequently, the suggested guidelines on prevention and suppression were employing an integration concept called the DDT Model (Destroy Drugs Trafficking Model) which consists of 3 dimensions: legal processes relating to drugs suppression, development of operational officers’ potentials, and offender rehabilitation to reduce the potential of reoffending.Item Open Access Accelerating MR imaging using deep learning on spatial frequency data(Mahidol University. Mahidol University Library and Knowledge Center, 2022) Sarattha Karnjanapreechakorn; Worapan Kusakunniran; Thanongchai Siriapisith; Pairash SaiviroonpornSince the invention of the MRI machine, slow signal acquisition has been a significant barrier to the MRI process in getting a high throughput. A parallel imaging technique is used to simultaneously reconstruct a final MR image after acquiring fewer raw data with multi-RF coils to overcome this problem. However, the parallel imaging still cannot accelerate enough to reduce the overall time significantly. Therefore, the deep convolution neural network is presented to reconstruct a high-quality MR image with higher acceleration factors in this research. The proposed Multi-Level Pooling Encoder-Decoder Network (MLPED Net) performs the reconstructions by encoding the acquired signals. Then the crucial part of the network, a Multi-Level Pooling module (MLP), is applied to filter irrelevant signals, followed by a decoder module to reconstruct the MR images. The proposed network can be trained end-to-end with a newly presented loss function, Dual-Domain Loss (DDL). The experimental results are based on the published fastMRI knee dataset and show that the proposed MLPED Net outperforms the competing methods for both 4- and 8-fold accelerations.Item Metadata only A phenomenological study of parental involvement in children’s homeschooling(Mahidol University. Mahidol University Library and Knowledge Center, 2021) Supakit Boonanegpat; Patreeya Kitcharoen; Poschanan Niramitchainont; Sovaritthon Chansaengsee; Arisara LeksansernThe objectives of this research were: (1) to study and describe parents’ lived experiences with parental involvement in children’s homeschooling, (2) to interpret and describe the various units of meanings from parents’ lived experiences with parental involvement in children’s homeschooling, and (3) to find and describe the essence(s) or the necessary invariable-components of parental involvement in children’s homeschooling. Hermeneutical phenomenology was employed as its research approach. Hence, series of in-depth phenomenological-interviews and close observations were carried out with 7 homeschool parents. It was found that parents’ understandings of the world, perceptions towards traditional education, and acceptance of homeschooling yield a conceptual relationship with how they execute their homeschooling practice with certain expectations. Thus, the essence of this phenomenon is how parents seek to be free from the education system, and attain full control in their children’s learning. This study pointed out how parents, governing bodies, and mainstream education can benefit from having a large body of knowledge in parental involvement. Discussion and recommendations are provided.Item Metadata only The best treatment for the management of hemodynamically significant patent ductus arteriosus in preterm neonates : a network meta-analysis and risk-benefit analysis(Mahidol University. Mahidol University Library and Knowledge Center, 2020) Sudarat Eursiriwan; Sakda Arj-Ong Vallibhakara; Ammarin Thakkinstian; Chusak Okaseharoen; Oraluck PattanaprateepVarious pharmacological treatments are available for preterm infants with patent ductus arteriosus (PDA) but their risks and benefits are controversial. This study aimes to identify the best treatment of PDA using network meta-analysis (NMA) and risk-benefit assessment (RBA). Relevant randomized controlled trials (RCTs) were identified from MEDLINE, Scopus, and Cochrane Library untill March 2019. RCTs were eligible if they studied in preterm (gestational age < 37 weeks) or low-birth-weight infants (weight < 2500 g) with pre-symptomatic PDA and hemodynamically significant PDA (hsPDA) compared to any pair with any dose/route of pharmacological treatments. The final outcomes were PDA-closure for benefit and any serious adverse effects (SAE) e.g., death, bronchopulmonary dysplasia, intraventricular hemorrhage, necrotizing enterocolitis, or retinopathy of prematurity. An NMA was used to estimate the relative risks of treatment effects. For the RBA, an incremental risk-benefit ratio (IRBR) was calculated by diving the incremental risk by benefit using data from NMA, and they were further jointly simulated using Monte Carlo methods with 1000 replications. A risk-benefit acceptability curve was constructed at varying acceptability thresholds. Sixtyone RCTs with hsPDA were eligible considering 15 different interventions. The NMA indicated that four interventions yielded high PDA closure and low SAE, i.e., a high dose of oral ibuprofen (HOB), standard dose of oral acetaminophen (SOA), oral ibuprofen (SOB), and continuous infusion of ibuprofen (SIBdrip) in comparison with indomethacin. In addition, given an acceptable threshold of 25%, i.e., having one SAE out of four PDA-closure, HOB had 72.40% (69.52, 75.15) being the highest probability of NCB, followed by SOA (68.40 (65.42, 71.27)), SOB (63.10 (60.02, 66.10)), and SIBdrip (59.60 (56.48, 62.66)). There were inadequate studies for pooling data of pre-symptomatic PDA. Trade-off RBA indicated that HOB, SOA, and SOB might be the treatments of choice for hsPDA for short-term clinical outcomes. Optimal high doses and long-term outcomes are needed to study further.Item Metadata only Pre-service teacher development of technological pedagogical content knowledge in teaching computer programming : design and practices of mobile-assisted games for secondary education(Mahidol University. Mahidol University Library and Knowledge Center, 2022) Chanayuth Changpetch; Patcharin Panjaburee; Khajornsak Buaraphan; Pratchayapong YasriThe concept of variables and loops is the fundamental concept for students in learning computer programming. There is less empirical research on pre-service teachers using mobile-assisted game-based learning (MAGBL) with computer programming learning. Therefore, this study aimed to address this shortcoming by providing empirical evidence for evaluating the computer programming knowledge of K-12 students leading to the design of a pre-service teacher course. This mixed-method study consisted of three phases; 1) Preliminary phase, a survey was conducted to investigate variable and loop misconceptions of 151 pre-service teachers and find the suitable programming-assisted tool. The data was collected by using misconceptions tests in three groups of different programming-assisted tools consisting of Logo (n = 22), Scratch (n = 73), and Python (n = 56). Data analysis was operated with Kruskal-Wallis and Mann-Whitney U tests. 2) Phase I, an experimental research method was employed used to identify the effectiveness of the card and board games with MAGBL in reducing variable and loop misconceptions of 107 secondary students. Misconception tests (MTs) and reflective essays (RE) were used to collect data. Data analysis was performed with frequency, one-way-repeated measures, pairwise comparisons, and thematic analysis. 3) Phase II, mixed methods research was used to examine teacher development course on computer programming with 36 pre-service teachers. This course consisted of 6 hours a day and lasted three days. The data was collected by using MTs, self-reported surveys on technological pedagogical content knowledge (TPCK), RE, and interview forms. Data analysis was performed with one-way-repeated measures, pairwise comparisons, and thematic analysis. The results of the three phases showed that Python and Scratch can better interpreted the misconceptions about variables and loops respectively. Moreover, the used of games with MAGBL revealed a significantly reduction in students’ misconceptions, understood the major misconception of each concept, and informed complications in both games. Furthermore, implementing games with MAGBL with activities in Phase II indicated that the pre-service teachers significantly understand both concepts and improved their four knowledge-related dimensions of TPCK after participating in the pre-service teacher course.Item Metadata only Performance analysis of darknet content clustering(Mahidol University. Mahidol University Library and Knowledge Center, 2022) Patipon Tapaneeyakul; Noppadol Wanichworanant; Tanasanee Phienthrakul; Mingmanas SivaraksaThis research demonstrates a performance analysis of the darknet content clustering. For darknet clustering, Latent Dirichlet Allocation (LDA), Latent Semantic Analysis (LSA), and K-means clustering were used as a set of natural language processing methods. Five services, which are a darknet spider service, a crawler service, a data preprocessing service, a data processor service, and a clustering service, were developed for our darknet clustering system. To verify clustering accuracy, darknet data were labeled then collected and clustered using Latent Dirichlet-allocation (LDA), Latent-semantic analysis (LSA), and K-mean clustering, respectively. Finally, the findings indicate that K-means clustering has been the most effective method for clustering darknet content. According to our experiments, the accuracy of the K-means clustering approach was 85.81 percent, the highest of the three methods.Item Metadata only Efficacy and economic evaluation of delivery of care with tele-continuous eeg in critically ill patients : a multicenter randomized controlled trial(Mahidol University. Mahidol University Library and Knowledge Center, 2022) Chusak Limotai; Oraluck Pattanaprateep; Atiporn Ingsathit; Ammarin ThakkinstianSome critically ill patients are confirmed by continuous electroencephalography (cEEG) monitoring that non-convulsive seizure (NCS) and/or non-convulsive status epilepticus (NCSE) are causes of their depressed level of consciousness. Meanwhile, the shortage of epilepsy specialists, especially in developing countries, is a major limiting factor in implementing cEEG in general practice. Delivery of care with tele-continuous EEG (tele-cEEG) may be a potential solution as this allows specialists from a central facility to remotely assist local neurologists from distant areas in interpreting EEG findings and suggesting proper treatment. No tele-cEEG program has been implemented to help improve the quality of care. Therefore, this study was conducted to assess the efficacy of implementing tele-cEEG in critical care. Objectives: 1) To ascertain the cumulative incidence of seizures detected by Tele-cEEG and Tele-routine EEG (Tele-rEEG) and 2) To assess the efficacy of Tele-cEEG on mortality and functional outcome as compared with Tele-rEEG Methods: This study was a 3-year prospective, randomized, controlled, parallel, multicentre, superiority trial comparing delivery of care through ‘Tele-cEEG’ intervention with ‘Tele-rEEG’ in patients with clinical suspicion of NCS/NCSE. A group of EEG specialists and a tele-EEG system were set up to remotely interpret EEG findings in eight regional government hospitals across Thailand. The primary outcomes were the detection rate of seizure detected by Tele-cEEG and Tele-rEEG, functional neurological outcome (modified Rankin Scale, mRS), and mortality rate. Functional outcome (mRS) was assessed at 3 and 7 days, and at 90 days, 6 months, 9 months, and 1 year after recruitment. Results: In total, 253 patients were randomized, 127 and 126 patients received Tele-cEEG and Tele-rEEG, respectively. Thirty-three patients with seizure tendency due to the presence of epileptiform discharges in Tele-rEEG arm were switched to receive Tele-cEEG. Overall, NCS and/or NCSE were detected in 46 (18.18%) patients, significantly more common in the Tele-cEEG arm than Tele-rEEG, with corresponding incidence of 22.05% vs 7.94% (p = 0.002). Regarding efficacy on mortality rate, all analyses with adjusting for NCS/NCSE detected and treatments after randomization including intention-to-treat with adjusted HR 0.907 (95% CI: 0.644 – 1.278; p = 0.578), per-protocol with adjusted HR 0.947 (95% CI: 0.650 – 1.379; p = 0.775), modified per-protocol with adjusted HR 1.005 (95% CI: 0.708 – 1.427; p = 0.977) and as-treated analyses with adjusted RR 0.882 (95% CI: 0.638 – 1.125; p = 0.376) did not show significant differences in mortality between Tele-cEEG and Tele-rEEG. Functional scores at > 6 months up to 9 months tended to be better in the Tele-cEEG than Tele-rEEG, i.e., 2.56 vs 3.17 (p = 0.035); however, this was not robust by other analyses, i.e., per-protocol and modified per-protocol analysis. Conclusion: Our findings showed that Tele-cEEG may be beneficial to detect NCS and/or NCSE, but did not improve clinical outcomes relative to Tele-rEEG. In the limited resource setting, we recommend applying at least Tele-rEEG in patients who are at risk for seizure, if there are seizures and/or presence of specific EEG features (i.e., epileptiform and/or periodic discharges) detected during Tele-rEEG recording, continued monitoring with Tele-cEEG may be performed.Item Metadata only A pathogenesis study related to the biofilm formation by candida albicans isolated from hemoculture using the zebrafish model of infection(Mahidol University. Mahidol University Library and Knowledge Center, 2022) Pokhrel, Sabi, 1991-; Popchai Ngamskulrungroj; Iyarit Thaipisutikul; Phoom Chairatana; Chalermchai MitrpantCandida albicans, an opportunistic pathogen, has the ability to form biofilm in the host or within the indwelling medical devices in their body. Biofilm has been associated with the disseminated disease with increased severity of infection by perturbing host immune response and prolonging the antifungal treatment. In this study, three strains with different biofilm-forming strengths, i.e., non- , weak- , and strong biofilm formers were assessed for in vivo virulence using the zebrafish model. Survival assay and fungal tissue burden were measured. Biofilm-related and immune- related gene expressions were also investigated. Survival of the zebrafish, inoculated with strong biofilm forming C. albicans, was significantly shorter compared to non- biofilm forming C. albicans strains. However, there was no statistical difference in colony forming unit tissue burden among groups of all three tested strains. We observed that C. albicans with different biofilm-forming in vitro capacity induced significantly different levels of biofilm-related genes associated with strains and showed significant differences in biofilm-related gene expression at an early time- point (8 h). Biofilm forming strain (140 and 57), injected in zebrafish larvae, possessed higher expression levels of genes associated with adhesion, attachment, filamentation, and cell proliferation, including eap1, als3, hwp1, bcr1, efg1, and mkc1 as well as genes associated with maturation (zap1), and dispersion (ume6 and nrg1). Furthermore, immune-related genes such as il-6, tgfb1r, tnf-α, and foxp3a were also up-regulated in zebrafish infected with strong biofilm forming strain at 24 h. The results suggested that despite different genetic backgrounds, biofilm formation is an important virulence factor for the pathogenesis of C. albicans. However, the association between the biofilm-forming strength and in vivo virulence based upon immune response is still controversial and needs to be further studied.Item Open Access Mother's work related to infant morbidity and mortality in Thailand(Mahidol University Library and Knowledge Center, 2014) Tiwarat Tor.Jarern; Yothin Sawangdee; Rossarin Gray; Aroonsri Moncholchati; Guang GuoA mother is the key caretaker of children in their early life. The relationship between the mother and her infant has an important impact on the infant's health and mortality. In recent times, the proportion of women in the workforce has increased responsibilities. Hence it is important to understand the relationship between the socioeconomic-occupation of mothers during late pregnancy and infant morbidity and mortality; in specific age groups; related to experiences of infant hospitalization within the first year of age; and their survival probability at that given time. This study is a prospective cohort study of Thai children (PCTC) during the period from 2000-2002. Data were collected, and a prospective cohort analysis was performed on mothers and infants, 4,155 and 4,245, respectively. In a multivariate analysis of infant morbidity, there was no significance between working and non-working mothers’ experiences with infant hospitalization. Although, those working mother in use one of the regarding by five socioeconomic-subgroups: non-work (unemployment), informal work, low occupations level (Blue collar), middle occupations level (high-waged Blue-collar jobs or low-waged White-collar jobs) and high occupations level (White-collar) subgroups showed that the significantly higher adds of having experienced infant's hospitalization among the high occupations level and non-working mothers (adjusted odds ratio (AOR) = 1.7), and overtime (AOR = 1.7) as per Generalized Estimating Equations (GEE). When considering infant morbidity during the 7-12 months of age, the middle and high occupational level subgroup compared to non-working mothers had an association with experienced infant hospitalization (AOR = 1.9 and 1.5 respectively). The mortality results of the Kaplan-Meier's analysis did not find the link between mother's work sub-groups and the death in neonatal or post-neonatal period, whereas the Fisher's Exact analysis or Chi-Square results did not find these relationships. However, some infant’s factors: gender, birth weight, and gestational age, previous experienced to hospital infant morbidity (prior to 3 months and 6 months of infant ages); bottle feeding; and DPT vaccine within first 6 months. Mother's age, mother's education; mother's household income per head quartile, and residential area of the mother were statistically significantly to infant morbidity. Furthermore, there are other infant mortality factors related to variables which include: visits to an ANC clinic, perinatal hospitalized infant morbidity, preterm birth (< 37 week of gestational age), and low birth weight (< 2,500 gram), and place of residence. In conclusion, the work responsibilities of pregnant mothers in the workforce had no statistically significant relationship with infant morbidity and mortality, while the high socioeconomic-occupational subgroups of mothers had a statistically significant association with experienced hospitalized infant morbidity compared to non-working mothers in the second half year of life and over an extended period of time. This evidence directs that benefits policy makers who are concerned with pregnant mothers’ employment, maternity leave of high occupational level and its affect on reducing experiences of having to be admitted into the hospital of infants in second half of their first year and over time. Thai public health staff should be concerned about the dynamic of mother's work subgroups throughout the first year of life.Item Open Access The thinking model in environmental ethics development of children in a mangrove community(Mahidol University Library and Knowledge Center, 2018) Jitikan Jinarak; Tassanee Ounvichit; Saowapa Pornsiripong; Yothin SawangdeeInculcation is not sufficient in developing environmental ethics to restrain environmental problems. Coining on learners’ capacity to think in their real-life context to innovate an alternative model, the study (1) appraised the prevailing situations relating to the development of environmental ethics of children in a mangrove community, (2) illustrated the thinking patterns of the children engaged in a pragmatist learning process, and (3) assessed changes in their environmental ethics. This ethnographic cum action research was conducted in the fragile mangrove community of Koh Klang in Krabi province. Data on the current development situations were obtained from 45 related residents identified by the snowball technique. Data related to the biography and learning behavior of 15 local primary school children who volunteered to partake in a pragmatist learning process were collected from their interviews and test results, interviews of 20 local residents and their parents and teachers, and participant observations. The data were categorized to portray their individual thinking patterns and related test results on their tendencies to change into egocentrics, homocentrics or ecocentrics. The Learn to Think on the Environmental Ethics was an innovation model which comprised eight steps; (1) Amassing self-confidence, (2) Reflecting on the value of mangrove ecological relations, (3) Reflecting on own standpoint towards the relations, (4) Reviewing the value and own standpoint, (5) Visualizing a new value and standpoint, (6) Setting own action plan, (7) Interacting with the society and environment, and (8) Reflecting on a new identity. The density and diversity of their thinking patterns have positive influences on their chances to develop into ecocentrics. More studies should address the sustainability of their environmental ethics and the development of learning managers’ ability in using questions to promote thinking on the environmental ethics.Item Open Access The role of media health literacy on lifestyle behaviors among young adolescents in Thailand(Mahidol University Library and Knowledge Center, 2021) Nongnuch Jindarattanaporn; Sureeporn Punpuing; Jongjit Rittirong; Sirinya PhulkerdThere is a limited evidence to indicate the factors which influence Media Health Literacy (MHL) and lifestyle behaviors [i.e., eating and physical activity (PA)].The objective of this study was to investigate the factors and MHL which influence eating and PA. The data were obtained from the Analysis Media Landscape, Media Consumption, and Media Heath Literacy (MHL) for the Thai children, aged 10-14years, a stratified two-stage sampling survey of the Thai young adolescent's, aged 10-14 years, using a Qualtrics Offline Survey application-assisted face-to-face interview. Multiple Regression and Logistic Regression were used to find the probability associated with the independent variables (i.e., socio-demographic characteristics of young adolescents and their guardians, media exposure, sources of health information, and key informants of health information), MHL, and lifestyle behaviors. The result found that gender, age, GPA, the number of media type accessed to health information, the received food information from family members, friends, and teachers were associated with MHL. MHL influenced the frequency of vegetable and fruit intake. Therefore, these factors should be addressed in policy formulation and implementation in order to promote the MHL and lifestyle behaviors among the young adolescents in Thailand.Item Open Access Family functioning in Thai families having children with down syndrome and its influencing factors(Mahidol University Library and Knowledge Center, 2019) Waranuch Pruktarat; Tassanee Prasopkittikun; Yajai Sitthimongkol; Nopporn VongsirimasFamilies of preschool children with Down syndrome (DS) face a number of challenges and demands from Down syndrome itself and normative transition during this age group. As a result, the family members, in particular the mothers as primary caregivers, experience pile-ups of stress that adversely affect the family functioning. The purpose of the current study was to examine the pattern of relationships among family demands, family hardiness, social support, family problem solving and coping, and family functioning in families of children with Down syndrome. A cross-sectional study based on the resiliency model of family stress, adjustment and adaptation with the use of convenience and network sampling techniques were employed. One hundred and twenty mothers as primary caregivers were recruited at Siriraj Hospital, King Chulalongkorn Memorial Hospital, and Rajanukul Institute. Self-administered questionnaires including demographic questionnaire, the Family Stressors and Strains Questionnaire, the Family Hardiness Index, the Social Support Questionnaire, the Family Crisis Oriented Personal Evaluation Scales, and the Chulalongkom Family Inventory were used for data collection. The descriptive statistics and path analysis were used for data analysis. The results revealed that family demands, family hardiness, and social support had direct effects on family functioning. Neither family hardiness nor social support had indirect effects on family functioning through family problem solving and coping. The proposed model of the current study presented a good fit to the empirical data and explained 47 percent of variance in family functioning. The study findings suggest that pediatric nurses should develop further intervention/program to serve this population by strengthening and equipping them with the essential skills to reduce stress and strains, and keep balancing of family functioning.Item Open Access Acculturation of Indonesia migrants in Thailand(Mahidol University Library and Knowledge Center, 2020) Muhammad Zamal Nasution; Sciortino, Rosalia; Sakkarin Niyomsilpa; Sureeporn PunpuingThis research focused on Indonesian migrants in Thailand. It aims to explore the dominantacculturation strategy as well as specific strategies of different groups. It also looked at the impact of network andtransnationalism on their adaptation in the host country. The choice of this topic was triggered by the rapid increaseof Indonesian migrants to Thailand in the last two decades due to greater regional integration, expansion oftransport connectivity, and internationalization of education. Half of this recent migration flow is in fact composedof students, and this raises interesting questions on whether their stay is a temporary or a more permanentmigration. The fact that many Indonesian migrants are Muslims, as Islam is the main religion of Indonesia whileThailand is a -Buddhist majority country, also makes it worth exploring their acculturation to a different culture andwhether the Indonesian perceive any socio-cultural barriers to their adaptation to the Thai society. As the first studyon a recent Indonesian migrant community in Thailand, this study aims to provide a general overview by collectingprimary data. The theoretical cornerstone of the research is John W Berry's (1997) concept of fourfoldacculturation, adjusted and combined with other relevant theories. The research included both quantitative andqualitative data collection methods. The quantitative data were derived from an online survey of 268 respondents,while the qualitative data came from literature review, in-depth interviews, focus group discussion, and directobservation. Findings indicate that, Indonesian migrants apply an integration strategy, and a separation strategy.Some differences were identified among specific groups of migrants. Indonesian housewives were more inclined toward separation when not engaged in entrepreneurial activities, and women in mixed marriages with a Thai national were more assimilated in Thai society. As the length of stay of Indonesian migrants in Thailand is generally less than five years (because of the large presence of students) so, most Indonesian migrants remain well-connected with their networks in Indonesia and are engaged in transnational activities. This fact is also due to the good technological and social media connectivity and a tight-knit Indonesian community in the neighborhoods around the Indonesian Embassy. This research fills a void in knowledge about Southeast Asian migrants in Thailand and in spite of some limitations, it does provide interesting insights for further research and for reflection on the current national, bilateral, and regional migration management systems.Item Metadata only The development of a support system for undergraduate students with visual impairment in higher education institutions(Mahidol University. Mahidol University Library and Knowledge Center, 2016) Tam Jatunam; Teeradej Chai-Aroon; Pimpa Kachondham; Pairuch BorvornsompongThe purpose of this research was to examine the current support services available for students with visual impairment, the essential needs to support the students with visual impairment as well as the policies in supporting students with visual impairment in the model higher education institutions. The research participants consisted of 227 students with visual impairment, 46 Members of staff, and 5 university administrators. The research instruments included two sets of questionnaires: one for students with visual impairment and another for the staff, and a interview schedule for university administrators. For data analysis procedure, descriptive statistics were used in analyzing general quantitative data, cluster analysis employed in categorizing the participants into three groups, while content analysis and coding approaches were performed in examining qualitative data. The findings showed that: (1) The current support services available for students with visual impairment could be classified into three groups: high support system (HSS) medium support system (MSS) and low support system (LSS) capability to accept students with visual impairment. All three groups had high capability to provide financial and social support, and had medium capability to provide friendly physical environment. (2) Students with visual impairment had five essential needs and were able to access support services in five domains including social support, financial support, friendly physical environment, testing accommodation, and general support from staff. (3) Regarding policies, the university administrators had approved the policies of the Higher Education Commission by establishing the disability support service centers, and disability support services were included as a part of educational quality assurance of the universities.Item Metadata only Incidence and predictors of progression in chronic kidney disease(Mahidol University. Mahidol University Library and Knowledge Center, 2024) Tadsaneewan Gantagad; Siriorn Sindhu; Chukiat Viwatwongkasem; Ketsarin UtriyaprasitChronic kidney disease usually causes a decline in kidney function and results end stage renal disease. The objective of the study consisted of determining the incidence of faster kidney disease progression and determining factors affecting on kidney disease progression among patients with chronic kidney disease. The samples in this study included 2,185 patients' medical records, and 360 patients with chronic kidney disease who visited outpatient clinic in eight hospitals located in one of the health area and Bangkok Metropolitan administration area. The results showed the incidence of faster kidney disease progression was 13.12 per 100 persons-years. The predicting factors of faster kidney disease progression were CKD knowledge 0.54 (95% CI 0.43 - 0.72, p < .01), self-management ability 0.79 (95% CI 0.71-0.88, p < .01), self-management support 0.12 (95% CI 0.06-0.25, p < .01). The paths of factors affecting kidney disease progression included CKD knowledge (β = 0.11, p < .001), self-management support were significant (β = 0.03, p < .001), path from the CKD knowledge to kidney disease progression were significant (β = -0.19, p < 0.05), path from self-management to kidney disease progression were significant (β = -0.15, p < .001). The results of the testing revealed Chi-square (χ2) = 2.06, df = 1, p = 0.15, RMSEA = 0.05, NFI = 0.98. The study result imply that health care provider including nurse may enhance the success of delaying the kidney function decline by providing CKD knowledge and self-management support. In addition, human resource allocation is necessary for health service system in both of quantity and quality of provider.Item Metadata only Buddhist-catholic relations in Thailand : 'Dialogue of life' of Bangkok Catholics towards Buddhists(Mahidol University. Mahidol University Library and Knowledge Center, 2019) Francis Chan Sze Ming, 1966-; Hubina, Milos; Kosuta, Matthew; Esteve, JuliaThis research was done to study attitudes of Bangkok Catholics toward Buddhists and how dialogue of life is manifested in the bigger context of Buddhist-Catholic relations in Thailand. The theoretical background and framework looked into some modern theories of dialogue, then examined Christian attitudes toward people of other religions through theology of religions. Various Vatican II and post-Vatican II documents were studied to help understand the official Church position, and the history of Buddhist-Catholic relations in Thailand were looked into to better appreciate the present situation of the relations. In-depth interviews were carried out with 29 subjects, 25 of whom were Catholics, to examine the Catholics' attitudes, positions, and views toward Buddhism and Thai Buddhists. It was found that the majority of the Catholics had an attitude of pluralism, and they adhered to official Church directives regarding evangelization and dialogue whenever these were practical and conducive for maintaining societal peace and harmony. Also, it was found that the Catholics had largely appropriated popular Thai Buddhist religious terminology and concepts, though not necessarily imbibing their full Buddhist meanings. Furthermore, it was also revealed that the friendship factor and avoidance of controversies were important aspects in the Catholics' relations with Buddhists, and the main aspect of dialoguing with Buddhists was ordinary living together, or dialogue of life. This study showed the significance of how a tiny minority Asian Church has adapted and assimilated to a dominant Buddhist majority sociocultural, politically, and even theologically.Item Metadata only Prevalence and distribution pattern of mood swings in Thai youth : school-based survey(Mahidol University. Mahidol University Library and Knowledge Center, 2024) Suleemas Angsukiattitavorn; Acharaporn Seeherunwong; Mathuros Tipayamongkholgul; Rungnapa PanitratMood Swings (MS) is a common feature widely discussed as a prodromal sub-symptom of mental problems and psychopathology. However, there is paucity of knowledge related MS. This school-based, cross-sectional study aimed to investigate the prevalence and distribution pattern of mood swings on personal determinants and contextual determinants among Thai youth. Questionnaires were provided by using smartphone to determine demographic data, personal determinants: family history of mental problems, bullying involvement, social media use, and substance use and contextual determinants: family structure and circumstance and school location. The participants were students (2,598) in high schools (1,382) and vocational schools (1,216) in Bangkok and central region of Thailand. Multi-stage stratified random sampling and the classroom cluster were used to determine the sample size. Analysis of variance, odd ratio, and hierarchical multiple logistic regression models were used for analysis. Results showed the prevalence of mood swings was 26.4%. It was most frequent among students in the vocational schools in Bangkok area (37.1%). The bivariate analysis showed a significance difference of distribution of MS on personal and contextual determinants. The distribution of MS could be found in adolescents who had risk behavior and residing in hazardous situation. The probabilities of MS in aged 15 - 24 years were: bullying involvement 36.9% (n=1,293), problematic social media use 55.9%(n=127), high expressed emotion in family 36.6%(n=1,256), and studying in vocational program 29.5%(n=1,216) and school located in Bangkok 32.4%(n=561). Also, substance use was probably a risk to MS such as cannabis 41.8%(n=55) and heroin 48.0%(n=25). In addition, the current study found significant hierarchical logistic regression analysis of female, family history of mental problems and illness, bullying involvement, problematic social media use, illicit substance use, high expressed emotion in family. Finally, an interaction between vocational program and metropolitan/ urban area impacted on mood swings (p < .05) when all included variables were controlled. The final model showed acceptable fit (X 2 =398.53, df=20, p=.106). Findings of the study indicate that the pattern of mood swings was associated with significant bullying involvement, problematic social media use, illicit substance use, family circumstance and school characteristics. The public need greater awareness of mood swings pattern and its alternative implications of MS screening. Moreover, early intervention for prevention of mental illness is needed.Item Metadata only A corpus-based study of antonym sequence in Japanese(Mahidol University. Mahidol University Library and Knowledge Center, 2018) Phornthip Nithithanawiwat; Isara Choosri; Pattama PatpongA corpus-based study of antonym sequencing in Japanese aimed: (1) to investigate antonym sequencing when co-occurring in one sentence; (2) to investigate the factors affecting antonym sequencing; (3) to examine whether the preferred ordering within antonym pairs is determined by frequency or not. This study tested 2 hypotheses. First, different frequency patterns of the order within antonym pairs in antonym sequences in Japanese follow the markedness principle; Second, more frequently used antonyms of antonym pairs occur more frequently in the preferred position within antonym sequences in Japanese. The data was collected from Tsukuba Web Corpus, and the test hypothesis regarding population proportion was used for the test statistic. The collected antonymous pairs were ordered according to predictive markedness properties, and they were tested by population proportion. The 131 antonym pairs (69 percent from total 191 pairs) which had p value below 0.05 may support the first hypothesis, that different frequency patterns of the ordered antonym pairs in antonym sequences in Japanese follow the principle of markedness. It was found that 7 factors based on the principle of markedness influenced sequencing, namely positivity, phonology, morphology, magnitude, chronology, spatial position and culture-specific factor. The later consists of yin-yang principle which is based on Chinese philosophy, uchi-soto and seniority. These three exist in the socio-cultural fabric of Japan. Uchi-soto notion is unique character of Japanese culture. It is reflected in real language use and appears in antonym sequencing such as kokunai 'domestic' prcedes kokusai 'international by 72%. It seems to provide priority of relationship with Japan (as uchi 'inside') more than other countries (as soto 'outside') following uchi-soto notion. Moreover, the word frequency influenced the preferred ordering of 85 antonym pairs in Japanese by 65 percent (from total 131 pairs), and it may be sufficient evidence to support the second hypothesis, that more frequently-used antonyms of antonym pairs occur more frequently in their preferred position within antonym sequences when co-occurring in one sentence in Japanese.Item Metadata only The music teacher training model for program trainers to develop lifelong learning competencies(Mahidol University. Mahidol University Library and Knowledge Center, 2024) Nicha Chansitthichok; Anak Charanyananda; Narongchai Pidokrajt; Treetip Boonyam; Pansak PolsaramThe music teacher training project supported by the government operates annually with restricted training contents, and shallow understanding of characteristics of music content leading to a limitation in music teacher development. This research aims to (1) explore the current status and structure of music teacher training, (2) construct a model of music teacher training for lifelong learning skills, and (3) develop the trainer's manual of music teacher training as a path to lifelong learning skills. This qualitative research collected data by interviewing 40 samples including music teachers, music trainers and music educators who were involved in music teacher training in 2017-2018, and observing music teacher training exercises. The result of this research found similarity in the type of training courses which mostly are set as a single training course with no continuity to higher level training. The observation and interview data were analyzed for creating the music teacher training model. The model consists of three parts (1) input information: training type, participants, course output, course content, and assessment (2) designing training process: the activities and details in training process, and (3) output: developing lifelong learning competencies